Unlocking the Potential of Tranexamic Acid Injection

Tranexamic acid, a medication that may seem complex at first glance, plays a crucial role in preventing and treating bleeding due to a process called fibrinolysis. This article aims to demystify Tranexamic acid, offering insights into its uses, precautions, and more. So, let’s embark on a journey to understand this medical marvel.

1. What is Tranexamic Acid and How Does It Work?

1.1 Definition and Classification

  • Tranexamic Acid: Belongs to a group of medicines known as antihaemorragics, antifibrinolytics, and amino acids.

1.2 Purpose and Application

  • Used in adults and children (above one year) to prevent and treat bleeding caused by fibrinolysis.

1.3 Specific Indications

  • Effective in diverse situations, including:
    • Heavy periods in women
    • Gastrointestinal bleeding
    • Haemorrhagic urinary disorders post prostate surgery or procedures affecting the urinary tract
    • Ear, nose, or throat surgery
    • Heart, abdominal, or gynaecological surgery
    • Bleeding after treatment with clot-dissolving medicines.

2. Preparing for Tranexamic Acid: What You Need to Know

2.1 Contraindications

  • Do not take Tranexamic acid if:
    • Allergic to it or any of its ingredients
    • Currently have a disease leading to blood clots
    • Have consumption coagulopathy, causing clotting throughout the body
    • Experience kidney problems
    • Have a history of convulsions

2.2 Special Considerations

  • Consult your doctor if you:
    • Have had blood in your urine
    • Are at risk of blood clots
    • Experience excessive clotting or bleeding
    • Have had convulsions in the past

2.3 Administration Recommendations

  • Avoid intrathecal and intraventricular injection and intracerebral application due to the risk of cerebral oedema and convulsions.

3. Interaction with Other Medications

  • Inform your healthcare provider if you are taking:
    • Medicines that help blood clot (antifibrinolytic medicines)
    • Medicines that prevent blood clotting (thrombolytic medicines)
    • Oral contraceptives

4. Pregnancy, Breastfeeding, and Fertility Considerations

  • If pregnant, breastfeeding, planning to conceive, or in doubt, consult your doctor before taking Tranexamic acid.
  • Tranexamic acid excreted in human milk; not recommended during breastfeeding.

5. Usage Guidelines: How to Use Tranexamic Acid

5.1 Dosage

  • Administered by slow injection into a vein.
  • Dosage for children based on weight.
  • No reduction in dosage for the elderly unless renal failure is evident.

5.2 Kidney Problems and Hepatic Impairment

  • Dose adjusted based on blood test results for serum creatinine level.

5.3 Method of Administration

  • Administer only into a vein; avoid injection into a muscle.

5.4 Overdose Concerns

  • If given more than the recommended dose, transient blood pressure lowering may occur. Consult a healthcare professional immediately.

6. Possible Side Effects: Understanding the Risks

  • Common Side Effects (May affect up to 1 in 10 people):
    • Nausea
    • Vomiting
    • Diarrhoea
  • Uncommon Side Effects (May affect up to 1 in 100 people):
    • Rash
  • Rare Side Effects (Frequency cannot be estimated):
    • Malaise with hypotension
    • Blood clots
    • Convulsions
    • Vision disturbances, including impaired colour vision
    • Allergic reactions

7. Storage Guidelines

  • Keep out of reach of children.
  • Do not use after the expiry date.
  • Store below 30°C in the original package.

8. Contents and Presentation

  • Active substance: Tranexamic acid (500 mg/5 mL).
  • Other ingredients: Dibasic Sodium Phosphate, Monobasic potassium phosphate, and Water for injection.
  • Tranexamic acid injection is presented in packs of 5 ampoules.

Conclusion: Navigating Tranexamic Acid for Better Health

In conclusion, Tranexamic acid stands as a valuable tool in preventing and treating bleeding disorders. Understanding its applications, precautions, and potential side effects empowers individuals to make informed decisions regarding their health. Always consult your healthcare provider for personalized guidance, ensuring that Tranexamic acid becomes a trusted ally in your journey towards well-being.

Disclaimer: This article is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for personalized guidance.