Understanding Tafixyl Solution for Injection, Used to Control Bleeding

Tafixyl Solution for Injection is a prescription medication used to prevent or treat excessive bleeding in various conditions. It contains the active drug tranexamic acid, which works by helping to stabilize clots and stop bleeding episodes.

Let’s review key information on what Tafixyl is used for, how it works, who should avoid it, and important administration and safety considerations.

What Conditions Is Tafixyl Approved To Treat?

Tafixyl Solution can be used in both adults and children over 1 year old for:

  • Heavy menstrual bleeding
  • Bleeding stomach ulcers
  • Hemorrhage after prostate surgery
  • Excessive bleeding during oral, nasal, abdominal, gynecological, or heart surgeries
  • To control bleeding after treatment with “clot-busting” thrombolytic drugs

It helps slow or stop bleeding episodes by blocking the breakdown of natural blood clots. But it does not treat any underlying condition causing the bleeding.

How Does the Tranexamic Acid in Tafixyl Work?

  • Tranexamic acid is an antifibrinolytic drug.
  • It works by inhibiting the breakdown of fibrin blood clots. Fibrin helps form clots by acting like a “mesh” that plugs breaks in blood vessel walls.
  • Tranexamic acid helps stabilize clots allowing better control of bleeding episodes.

By slowing down the process that normally breaks down clots (called fibrinolysis), vessels can seal up leaks more effectively.

What Are Possible Side Effects of Tafixyl?

Along with helping control bleeding, Tafixyl may potentially cause some unwanted side effects including:

  • Nausea, vomiting, diarrhea
  • Dizziness from lowering blood pressure
  • Allergic reaction
  • Seizures
  • Blood clots
  • Vision changes

Promptly inform your doctor if you experience any unusual or serious reactions while being treated with Tafixyl. They will evaluate if it remains appropriate for you or if dosage adjustments are needed.

Who Should Not Use Tafixyl Solution?

You should not use Tafixyl if:

  • You have a personal or family history of blood clots
  • You have current blood clots
  • You have ever had an allergic reaction to tranexamic acid
  • You have severe kidney dysfunction

Tafixyl also comes with cautions if you have any bleeding risks or history of seizures. Use is not recommended while breastfeeding. Discuss your medical history thoroughly with your doctor before using this medication.

How Is Tafixyl Administered Properly?

  • Tafixyl injection must be given intravenously as a slow bolus or infusion
  • The standard adult dose is 1 gram (10 mL) injected slowly 3-4 times daily
  • Your doctor will calculate the dose based on your body weight if needed
  • Children over age 1 also require weight-based dosing
  • Treatment typically continues for up to 2 weeks depending on the condition
  • Tafixyl should NOT be injected into the muscle or other routes

Carefully follow all instructions from your medical team on proper dose, timing, infusion rate and duration for your situation.

Can Tafixyl Interact With My Other Medications?

It’s important to inform your doctor about ALL medications, vitamins and supplements you take. Tafixyl can potentially interact with:

  • Anticoagulants or “blood thinners”
  • Hormonal contraceptives
  • Any other drugs impacting clotting factors

Combining tranexamic acid along with these other agents may increase risks for clots or bleeding complications. Your doctor may request more frequent monitoring of bloodwork while on therapy.

In Conclusion: Using Tafixyl Cautiously Under Medical Supervision

I hope this overview gives you a helpful introduction to understanding what Tafixyl Solution for Injection is used for, how it works, key precautions, and proper administration. As with any IV medication impacting bleeding and clotting, close monitoring and cautious use alongside doctor supervision is imperative. Promptly report any concerns or side effects from therapy for evaluation.

Frequently Asked Questions About Tafixyl

Along with the key details on Tafixyl’s usage, you may have additional questions. Below are answers to several frequently asked questions for more help and information.

Why Monitor Vision With Long Term Tafixyl Use?

In some cases, extended Tafixyl use for more than several weeks may cause changes in color vision detected on eye exams. The cause is unknown. For safety, regular ophthalmology evaluations are advised to catch any retinal or vision changes early if using beyond 2 weeks.

How Long Does Tafixyl Take To Work?

Onset of action is typically seen fairly rapidly once injected intravenously, usually within 30 minutes to 3 hours after administration. Effects diminish around 7 to 9 hours later which is why scheduled repeat dosing is needed 2 to 4 times daily.

Duration varies based on dosage, site of bleeding, and other patient factors. Your doctor will tailor timing of doses for your situation.

What If More Than The Recommended Dose Is Given?

Accidental overdose of Tafixyl can lower blood pressure to dangerously low levels. Symptoms like dizziness, rapid heart rate, confusion and fainting may happen which require emergency medical care.

If you have symptoms of overdose after any dose of Tafixyl, immediately contact your doctor, nurse, or go to the nearest emergency room. Bring the medication vial with you if possible. Prompt supportive treatment can counteract the blood pressure effects.