Calmagine tablets for relief of cold and flu symptoms

Calmalgin tablets contain a combination of three active substances. The active compounds in Calmalgin tablets relieve symptoms of nasal congestion, increased secretion, and high temperature associated with the following conditions:

  • Colds and flu.
  • Allergies of the upper respiratory tract, such as rhinitis and sinusitis of all kinds, sore throat, laryngitis, and otitis media.


One tablet of Calmalgin contains the following active ingredients:

  • 325 milligrams of paracetamol: a substance that has an effective and rapid effect to relieve pain and reduce high body temperature, and it does not cause any of the side effects that accompany the use of aspirin, such as stomach irritation.
  • 25 mg of phenylephrine hydrochloride: A compound that removes congestion and stuffy or runny nose associated with colds, influenza, rhinitis and allergies.
  • 2 milligrams of chlorpheniramine maleate: an anti-allergic compound, which is rapidly absorbed in the body and reaches its maximum effect in a short period.

Important warning

Calmalgin tablets may cause drowsiness and a decreased ability to concentrate, so you should exercise caution when engaging in any activity that requires mental alertness, including driving a vehicle or operating machinery. Don’t do any activity that requires mental alertness until you are sure you can do it safely.

The hypnotic effect and decreased ability to concentrate associated with taking Calmalgin tablets increases when the drug is taken with alcoholic beverages, or with sedatives, hypnotics, or epilepsy drugs.

Instructions for use

If you take Calmalgin, without a prescription, you should carefully read the enclosed leaflet attached to the product, with the necessity to adhere to the instructions and recommended doses, which are written in that leaflet attached to the medicine package.

Calmalgin can be taken with or without food. Taking this medicine on an empty stomach will allow the medicine to work faster. Calmalgin tablets should be taken with a sufficient amount of water.

The effects of Calmalgin tablets begin to appear within 30 minutes, and the maximum effect occurs within 1 to 2 hours, and lasts from 4 to 6 hours.

Do not take more doses than those prescribed by your doctor, or those prescribed in the enclosed leaflet attached to the medicine package, because increasing the dose will not lead to an increase in the therapeutic effect, but it will increase the possibility of side effects.

Do not use Calmalgin tablets on your own (without consulting a doctor) for more than 7 days. See a doctor if your condition does not improve or if it gets worse.

Do not use this medicine after the expiry date which is stated on the package.

This medicine should be stored at a temperature between 20 and 25 degrees Celsius.

You should avoid taking Calmalgin with other cold and cough medicines.

If you forget to take a dose, take it as soon as you remember, unless it is almost time for your next dose, in which case you should miss the missed dose, continue with your normal dosing schedule, and do not take a double dose to make up for a missed dose.

Make sure to keep Calmalgin tablets out of the reach of children.

Side effects

The most common side effects, which are associated with the use of Calmalgin, include the following:

  • Rapid heart rate or irregular heartbeat.
  • Mood changes.
  • Dry mouth .
  • Blurred vision.
  • weakness.
  • Feeling short of breath.
  • Urinating less often than usual or having difficulty urinating.

If any of the above-mentioned effects worsen or persist for a long time, you should inform your doctor.

Precautions and warnings

Do not take Calmalgin if you are taking monoamine oxidase inhibitors, which are a class of drugs used to treat depression, known as MAOIs, and you should not take Calmalgin if you are taking any medications that belong to this class of antidepressants, or you have stopped taking  in the previous 14 days. Taking Calmalgin with other monoamine oxidase inhibitors (MAOIs) can cause serious, potentially life-threatening reactions.

Calmalgin should be used with caution in :

  • epilepsy,
  • increased intraocular pressure including glaucoma,
  • enlarged prostate gland,
  • severe hypertension or cardiovascular disease,
  • bronchitis and asthma,
  • liver disease,
  • thyrotoxicosis (high thyroid hormone). .

Before taking Calmalgin, make sure you tell your doctor or pharmacist about all the medicines you are taking, including over-the-counter and herbal medicines.

Calmalgine tablets
Calmalgine tablets

Pregnancy and lactation

There is no evidence of the safety of Calmalgin tablets during pregnancy, so it should not be used unless necessary, and when the expected benefits outweigh the potential risks to the fetus.

Calmagin may lead to inhibition of milk production from the breast during the lactation period, in addition to that it may be excreted in breast milk and affect the infant.

كالمالجين لتخفيف أعراض البرد و الأنفلونزا