What is VASOTAL?
VASOTAL is a medication used to improve blood flow and reduce symptoms associated with certain circulatory problems. It is available in various forms and strengths, including VASOTAL 100MG/5ML 1 AMP. (6.5 L.E.), VASOTAL 300MG/15ML AMP. (10.5 L.E.), and VASOTAL 400MG SR 20 F.C. TABS. (22 L.E.). The active ingredient in VASOTAL is Pentoxifylline, which belongs to the pharmacological group of anti-ischemic agents. This medication is manufactured by UP PHARMA.
How does VASOTAL work?
VASOTAL works by improving blood flow to various parts of the body. Pentoxifylline, the active ingredient, helps to decrease the viscosity (thickness) of blood, making it easier for blood to flow through narrowed or constricted blood vessels. This action can help to reduce symptoms such as pain, cramping, and numbness that are often associated with poor circulation.
What is VASOTAL used for?
VASOTAL is primarily used to treat intermittent claudication, a condition characterized by pain and cramping in the legs due to poor blood flow. It is also used to improve blood flow in other parts of the body, such as the brain and heart, which can help to reduce symptoms associated with various circulatory disorders.
Approved Uses
- Intermittent Claudication: This is the most common use of VASOTAL. It helps to alleviate pain and discomfort in the legs, allowing individuals to walk farther and with less pain.
- Peripheral Artery Disease (PAD): VASOTAL can be used to improve blood flow in individuals with PAD, a condition where the arteries in the legs become narrowed or blocked.
Potential Off-Label Uses
- Cerebrovascular Disease: Some healthcare providers may prescribe VASOTAL to improve blood flow to the brain, although this is not an approved use.
- Heart Disease: In some cases, VASOTAL may be used to improve blood flow to the heart, although this is also an off-label use.
Dosage and Administration
The dosage of VASOTAL can vary depending on the specific condition being treated and the individual’s response to the medication. It is important to follow your doctor’s instructions carefully when taking VASOTAL.
Common Dosages
- For Intermittent Claudication: The usual starting dose is 400 mg three times a day. Your doctor may adjust the dose based on your response to the medication.
- For Peripheral Artery Disease (PAD): The recommended dose is typically 400 mg three times a day, but this can be adjusted by your doctor.
How to Take VASOTAL
- Oral Tablets: VASOTAL tablets should be taken with food to reduce the risk of stomach upset. Swallow the tablets whole with a full glass of water.
- Intravenous Injection: In some cases, VASOTAL may be administered via intravenous injection in a hospital setting. This is typically done under the supervision of a healthcare professional.
Potential Side Effects
Like all medications, VASOTAL can cause side effects, although not everyone experiences them. It is important to be aware of the potential side effects and to contact your doctor if you experience any serious or bothersome symptoms.
Common Side Effects
- Nausea
- Vomiting
- Stomach upset
- Dizziness
- Headache
- Flushing (redness and warmth in the face)
Serious Side Effects
- Chest pain
- Irregular heartbeat
- Severe allergic reaction (rash, itching, swelling, difficulty breathing)
- Bleeding or bruising easily
If you experience any of these serious side effects, seek medical attention immediately.
Precautions and Contraindications
VASOTAL should not be used by everyone. It is important to discuss your medical history with your doctor before starting this medication.
When Not to Use VASOTAL
- Allergy to Pentoxifylline: Do not take VASOTAL if you are allergic to Pentoxifylline or any of the other ingredients in the medication.
- Bleeding Disorders: VASOTAL can increase the risk of bleeding, so it should be used with caution in individuals with bleeding disorders or those taking blood-thinning medications.
- Severe Liver or Kidney Disease: VASOTAL should be used with caution in individuals with severe liver or kidney disease, as it may not be safely metabolized and excreted.
Precautions
- Pregnancy and Breastfeeding: The safety of VASOTAL during pregnancy and breastfeeding has not been established. Discuss the potential risks and benefits with your doctor.
- Elderly Patients: Elderly patients may be more sensitive to the side effects of VASOTAL, so a lower dose may be recommended.
Drug Interactions
VASOTAL can interact with other medications and substances, which can affect how it works or increase the risk of side effects. It is important to inform your doctor about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.
Potential Interactions
- Blood-Thinning Medications: VASOTAL can increase the risk of bleeding when taken with blood-thinning medications such as warfarin or aspirin.
- Cimetidine: This medication can increase the levels of Pentoxifylline in the blood, which may increase the risk of side effects.
- Theophylline: VASOTAL can increase the levels of theophylline in the blood, which may increase the risk of side effects such as nausea, vomiting, and irregular heartbeat.
Warnings
It is important to be aware of the following warnings when taking VASOTAL:
- Bleeding Risk: VASOTAL can increase the risk of bleeding, so it should be used with caution in individuals with bleeding disorders or those taking blood-thinning medications.
- Dizziness and Drowsiness: VASOTAL can cause dizziness and drowsiness, so it is important to avoid driving or operating heavy machinery until you know how the medication affects you.
- Alcohol: Avoid drinking alcohol while taking VASOTAL, as it can increase the risk of side effects such as dizziness and drowsiness.
What Should I Do If I Miss a Dose?
If you miss a dose of VASOTAL, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Long-Term Management
VASOTAL is typically used for long-term management of circulatory problems. It is important to follow your doctor’s instructions carefully and to attend all scheduled follow-up appointments. Your doctor may monitor your progress and adjust your dose as needed.
What to Expect with Continued Use
- Improved Blood Flow: With continued use, VASOTAL can help to improve blood flow and reduce symptoms associated with poor circulation.
- Regular Monitoring: Your doctor may order regular blood tests to monitor your liver and kidney function, as well as to check for any signs of bleeding.
Storage Information
Store VASOTAL at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Do not use VASOTAL if the expiration date on the package has passed.
Proper Disposal
Do not flush VASOTAL down the toilet or pour it down the drain. Properly discard this medication when it is no longer needed or has expired. Consult your pharmacist or local waste disposal company for more information about how to safely dispose of VASOTAL.
Price
VASOTAL is available in various forms and strengths, each with its own price:
- VASOTAL 100MG/5ML 1 AMP.: 6.5 L.E.
- VASOTAL 300MG/15ML AMP.: 10.5 L.E.
- VASOTAL 400MG SR 20 F.C. TABS.: 22 L.E.
Frequently Asked Questions (FAQs)
1. What is VASOTAL used for?
VASOTAL is primarily used to treat intermittent claudication, a condition characterized by pain and cramping in the legs due to poor blood flow. It is also used to improve blood flow in other parts of the body, such as the brain and heart, which can help to reduce symptoms associated with various circulatory disorders.
VASOTAL works by improving blood flow to various parts of the body. Pentoxifylline, the active ingredient, helps to decrease the viscosity (thickness) of blood, making it easier for blood to flow through narrowed or constricted blood vessels. This action can help to reduce symptoms such as pain, cramping, and numbness that are often associated with poor circulation.
2. How should I take VASOTAL?
VASOTAL should be taken exactly as prescribed by your doctor. The usual starting dose is 400 mg three times a day, but your doctor may adjust the dose based on your response to the medication. VASOTAL tablets should be taken with food to reduce the risk of stomach upset. Swallow the tablets whole with a full glass of water.
- Take VASOTAL with food to reduce the risk of stomach upset.
- Swallow the tablets whole with a full glass of water.
- Do not crush, chew, or break the tablets.
- Take VASOTAL at the same time each day to maintain consistent levels of the medication in your blood.
3. What are the common side effects of VASOTAL?
The most common side effects of VASOTAL include:
- Nausea
- Vomiting
- Stomach upset
- Dizziness
- Headache
- Flushing (redness and warmth in the face)
These side effects are usually mild and go away on their own. However, if they become bothersome or persistent, contact your doctor.
4. Can I take VASOTAL if I am pregnant or breastfeeding?
The safety of VASOTAL during pregnancy and breastfeeding has not been established. It is important to discuss the potential risks and benefits with your doctor before taking VASOTAL if you are pregnant or breastfeeding. Your doctor can help you make an informed decision based on your individual circumstances.
5. What should I do if I miss a dose of VASOTAL?
If you miss a dose of VASOTAL, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
6. Can I drink alcohol while taking VASOTAL?
It is best to avoid drinking alcohol while taking VASOTAL, as it can increase the risk of side effects such as dizziness and drowsiness. Alcohol can also interfere with the medication’s effectiveness and increase the risk of bleeding. If you have any questions about alcohol consumption while taking VASOTAL, consult your doctor.
7. How should I store VASOTAL?
Store VASOTAL at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Do not use VASOTAL if the expiration date on the package has passed. Properly discard this medication when it is no longer needed or has expired.
8. What should I do if I experience serious side effects while taking VASOTAL?
If you experience serious side effects such as chest pain, irregular heartbeat, severe allergic reaction, or bleeding, seek medical attention immediately. These side effects can be life-threatening and require prompt medical intervention.
9. Can VASOTAL interact with other medications?
VASOTAL can interact with other medications and substances, which can affect how it works or increase the risk of side effects. It is important to inform your doctor about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Some medications that can interact with VASOTAL include blood-thinning medications, cimetidine, and theophylline.
10. How long does it take for VASOTAL to work?
The effects of VASOTAL may not be immediately noticeable, as it can take time for the medication to improve blood flow and reduce symptoms. It is important to take VASOTAL as prescribed by your doctor and to attend all scheduled follow-up appointments. Your doctor can monitor your progress and adjust your dose as needed.
Disclaimer
The information provided in this blog post is for general knowledge and informational purposes only and does not constitute medical advice. Readers should always consult with a qualified healthcare professional for any health concerns or before making any decisions related to their health or treatment. The accuracy of the information is not guaranteed, and it may not reflect current medical guidelines or practices. Always follow the advice of your healthcare provider and the instructions that come with your medication.
Dr. Ahmad Baker, PharmD
Senior Pharmacist & Health Educator
With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.
Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.

