Psoriasis is a chronic autoimmune skin condition that causes raised, red, scaly patches on the skin. It is a relatively common condition, affecting about 2-3% of the population worldwide. While psoriasis isn’t contagious, it can be a frustrating and embarrassing condition to deal with. There are several different treatment options available for psoriasis, and Tazaro gel is one of them.
This comprehensive guide will explore everything you need to know about Tazaro gel for psoriasis, including its uses, effectiveness, how to use it, and potential side effects.
We will also discuss who should not use Tazaro gel, answer frequently asked questions, and explore alternative treatment options for psoriasis.
Tazaro gel: Key Features
Tazaro 0.1% Gel is a topical medication used to treat mild to moderate plaque psoriasis affecting up to 10% of the body surface. The active ingredient, Tazarotene, works by modulating gene expression, impacting cell proliferation and differentiation. It should be applied once daily to affected areas, avoiding healthy skin. Treatment duration typically lasts up to 12 weeks, with clinical experience for up to 12 months. The gel is contraindicated during pregnancy and breastfeeding, and should not be used on certain types of psoriasis or sensitive skin areas. Common side effects include skin irritation, pruritus, and erythema.
Key Points:
- Indications: Treats mild to moderate plaque psoriasis (up to 10% body surface).
- Application: Apply once daily in the evening, only to affected skin.
- Dosage: Start with 0.05% to assess tolerance, then 0.1% if needed.
- Contraindications: Not for use in pregnancy, breastfeeding, certain types of psoriasis.
- Precautions: Avoid application to healthy skin, eczematous, or inflamed areas; avoid UV exposure.
- Adverse Effects: Commonly causes skin irritation, pruritus, erythema.
- Clinical Efficacy: Improvement seen in 65% of patients after 12 weeks; effects visible in as early as 1 week.
- Storage: Store below 30°C, with a shelf life of 3 years.
- Manufacturer: Egyptian Group for Pharmaceutical Industries Co. – Egypt
What is Psoriasis and How Can Tazaro Gel Help?
Understanding Psoriasis
Psoriasis is an autoimmune disease that affects the skin. In people with psoriasis, the immune system sends faulty signals that cause skin cells to grow too quickly. This rapid growth creates a buildup of skin cells on the surface, forming the thick, red, and scaly patches that are characteristic of psoriasis.
Psoriasis can appear anywhere on the body, but it most commonly affects the elbows, knees, scalp, and lower back. There are five main types of psoriasis:
- Plaque psoriasis: This is the most common type of psoriasis, accounting for about 80% of cases. It causes raised, red, scaly patches on the skin.
- Guttate psoriasis: This type of psoriasis is often triggered by a bacterial infection, such as strep throat. It causes small, red, teardrop-shaped spots to develop on the skin, especially on the torso and limbs.
- Inverse psoriasis: This type of psoriasis affects smooth areas of the body, such as the armpits, groin, and genitals. It causes smooth, red, inflamed patches of skin.
- Pustular psoriasis: This type of psoriasis causes white pustules (pus-filled bumps) to form on red, inflamed skin.
- Erythrodermic psoriasis: This is the most severe type of psoriasis. It causes widespread redness, peeling, and swelling of the skin.
While psoriasis isn’t curable, there are effective treatments available to manage the symptoms and improve quality of life. Treatment options can include topical medications like Tazaro gel, light therapy, and oral medications.
Tazaro Gel: A Topical Treatment for Psoriasis
Tazaro gel is a topical medication used to treat mild to moderate plaque psoriasis. It contains the active ingredient tazarotene, which belongs to a class of medications called retinoids. Retinoids are synthetic derivatives of vitamin A that have a variety of effects on the skin.
In the case of psoriasis, tazarotene is thought to work by:
- Slowing down the growth of skin cells
- Reducing inflammation
- Normalizing the differentiation of skin cells
Tazaro gel is available by prescription only. It comes in two strengths: 0.05% and 0.1%. The doctor will determine the appropriate strength for you based on the severity of your psoriasis.
Using Tazaro Gel Effectively: Dosage, Application, and Important Tips
Tazaro gel is a prescription medication, so it’s important to use it exactly as directed by your doctor. Here’s a breakdown of what you need to know about using Tazaro gel for optimal results:
Dosage:
- Tazaro gel typically starts with the lower concentration (0.05%) to assess your skin’s tolerance before potentially progressing to the 0.1% strength if necessary.
- The doctor will determine the appropriate dosage based on your individual needs and the severity of your psoriasis.
Application:
- Apply a thin film of Tazaro gel once daily, in the evening, to the affected areas of your skin only.
- Avoid applying Tazaro gel to healthy skin or skin folds such as your armpits or groin area.
- Wash your hands thoroughly after applying the gel to prevent accidental transfer to your eyes or other sensitive areas.
- If you accidentally get Tazaro gel in your eyes, rinse them with clean water for 15 minutes.
Treatment Duration and Tips:
- The usual treatment period with Tazaro gel is up to 12 weeks. However, your doctor will determine the optimal duration based on your response to the medication.
- It’s important to be patient, as Tazaro gel may take several weeks to show noticeable improvement.
- To minimize irritation, especially during the initial application weeks, you can use an emollient (a moisturizer without any medication) on the areas surrounding the treated psoriasis plaques.
- Sunburn can worsen psoriasis. Be sure to protect your skin from the sun by wearing sun-protective clothing and using sunscreen with an SPF of 30 or higher while using Tazaro gel.
Here are some additional tips to keep in mind when using Tazaro gel:
- Do not use Tazaro gel if you are pregnant or breastfeeding.
- Inform your doctor about all medications you are currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Tazaro gel may interact with certain medications.
- Avoid excessive exposure to ultraviolet (UV) light, including sunlight, tanning beds, and PUVA therapy, while using Tazaro gel.
- If you experience any severe skin irritation after applying Tazaro gel, discontinue use and consult your doctor immediately.
By following these guidelines and using Tazaro gel as directed by your doctor, you can effectively manage your psoriasis symptoms and achieve clearer, smoother skin.
Potential Side Effects of Tazaro Gel and When to Seek Medical Attention
Tazaro gel is generally well-tolerated, but like all medications, it can cause side effects. Here’s a breakdown of the potential side effects of Tazaro gel and when to seek medical attention:
Common Side Effects:
The most frequently reported side effects of Tazaro gel include:
- Skin irritation: This can manifest as itching, burning, redness, stinging, dryness, peeling, or scaling at the application site. These side effects are usually mild and temporary and tend to improve with continued use.
- Worsening of psoriasis: In some cases, psoriasis may appear worse initially after starting Tazaro gel. This is a temporary phenomenon known as “psoriatic flare.” If your psoriasis worsens significantly or persists for more than a few weeks, consult your doctor.
Serious Side Effects:
While less common, some more serious side effects can occur with Tazaro gel. These include:
- Severe skin irritation: If you experience severe burning, blistering, or swelling at the application site, discontinue use of Tazaro gel and consult your doctor immediately.
- Allergic reaction: Signs of an allergic reaction may include hives, difficulty breathing, or swelling of the face, lips, or tongue. Seek emergency medical attention if you experience any of these symptoms.
When to See a Doctor:
It’s important to consult your doctor if you experience any of the following:
- Any severe or persistent side effects
- Signs of infection, such as redness, swelling, or pus at the application site
- If your psoriasis worsens significantly or does not improve after several weeks of treatment with Tazaro gel
Remember, this is not an exhaustive list of side effects. It’s always best to discuss any concerns you have about Tazaro gel with your doctor. They can advise you on the best course of action based on your individual situation.
Who Should Not Use Tazaro Gel (Contraindications) and Important Interactions
Tazaro gel is not suitable for everyone. Here’s a breakdown of who should not use Tazaro gel and potential interactions with other medications:
Contraindications:
- Allergy: If you have a known allergy to tazarotene or any other ingredients in Tazaro gel, you should not use it.
- Pregnancy and breastfeeding: Tazaro gel is contraindicated during pregnancy and breastfeeding due to the potential risk of birth defects. Women of childbearing potential should use effective birth control while using Tazaro gel and for at least one month after discontinuing treatment.
- Psoriatic pustulosa and psoriasis exfoliativa: Tazaro gel is not recommended for these specific types of psoriasis.
- Application on intertriginous areas, face, or scalp: Avoid using Tazaro gel on areas like the armpits, groin, face, or scalp.
Drug Interactions:
Tazaro gel can interact with certain medications. It’s important to inform your doctor about all medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, before starting Tazaro gel.
Here are some potential interactions to be aware of:
- Other topical medications: Concomitant use of other topical medications that cause irritation or drying should be avoided, as this can worsen skin irritation caused by Tazaro gel.
- Oral retinoids: Combining Tazaro gel with oral retinoids may increase the risk of side effects.
Your doctor will determine if Tazaro gel is safe for you to use based on your individual medical history and current medications.
Tazaro Gel vs Other Treatment Options: Exploring Alternatives for Psoriasis
While Tazaro gel can be an effective treatment for mild to moderate plaque psoriasis, it’s not the only option available. Here’s a look at some alternative treatment options for psoriasis:
Other Topical Medications:
- Corticosteroids: Corticosteroid creams and ointments are a mainstay treatment for psoriasis. They help to reduce inflammation and itching. However, long-term use of corticosteroids can thin the skin, so they are typically used for short periods or in combination with other medications.
- Calcipotriol: Calcipotriol is a synthetic form of vitamin D that helps to slow down the growth of skin cells. It is available in ointment, cream, and lotion forms.
- Coal tar: Coal tar products are available over-the-counter in shampoos, ointments, and lotions. They can help to reduce scaling and itching associated with psoriasis. However, coal tar can have a strong odor and can stain clothing.
Light Therapy (Phototherapy):
Light therapy involves exposing the skin to ultraviolet (UV) light from a natural or artificial source. This can help to slow down the growth of skin cells and reduce inflammation. There are different types of light therapy, and the best type for you will depend on the severity and location of your psoriasis.
Oral Medications:
For more severe cases of psoriasis, oral medications may be prescribed. These medications work systemically to suppress the immune system and reduce inflammation throughout the body. Some examples of oral medications used for psoriasis include methotrexate, cyclosporine, and acitretin.
Biologic Drugs:
Biologic drugs are a newer class of medications that target specific parts of the immune system involved in psoriasis. They are typically used for moderate to severe psoriasis that has not responded well to other treatments. Biologic drugs are administered by injection or infusion.
Choosing the Right Treatment:
The best treatment option for you will depend on several factors, such as the severity and type of your psoriasis, your overall health, and your lifestyle. It’s important to discuss all available treatment options with your doctor to determine the best course of action for managing your psoriasis.
Additional Considerations:
- Complementary and Alternative Therapies: Some people with psoriasis find relief from complementary and alternative therapies, such as stress management techniques, fish oil supplements, and Dead Sea baths. However, it’s important to talk to your doctor before starting any complementary or alternative therapies, as they may interact with your medications or other treatments.
- Lifestyle Changes: Certain lifestyle changes can also help to improve psoriasis symptoms. These include managing stress, maintaining a healthy weight, getting enough sleep, and avoiding smoking and alcohol.
By working with your doctor and exploring all available treatment options, you can find an effective way to manage your psoriasis and achieve clearer, more comfortable skin.
Conclusion: Finding Relief with Tazaro Gel and Beyond
Tazaro gel can be a valuable tool in managing mild to moderate plaque psoriasis. It offers a topical approach that can effectively reduce symptoms and improve quality of life. However, it’s important to remember that Tazaro gel may not be suitable for everyone, and there are other treatment options available.
Here’s a quick recap of the key points to consider:
- Tazaro gel works by slowing down skin cell growth, reducing inflammation, and normalizing skin cell differentiation.
- It is available by prescription only in two strengths: 0.05% and 0.1%.
- For optimal results, Tazaro gel should be applied once daily in the evening to affected areas only.
- Common side effects include skin irritation, which usually improves with continued use.
- Tazaro gel is not suitable for pregnant or breastfeeding women, people with certain skin conditions, or those allergic to any ingredients in the medication.
- If you experience any severe side effects, discontinue use and consult your doctor immediately.
Remember, psoriasis is a chronic condition, and there is no cure. However, with a combination of treatment options and lifestyle modifications, you can effectively manage your psoriasis and achieve long-term relief.
Beyond Tazaro gel, there are various treatment avenues to explore, including:
- Other topical medications: corticosteroids, calcipotriol, coal tar.
- Light therapy: using natural or artificial UV light to slow skin cell growth.
- Oral medications: for more severe cases, medications like methotrexate can suppress the immune system and reduce inflammation.
- Biologic drugs: target specific parts of the immune system involved in psoriasis.
- Complementary and alternative therapies: stress management, fish oil supplements, Dead Sea baths (always discuss with your doctor first).
- Lifestyle changes: managing stress, maintaining a healthy weight, getting enough sleep, avoiding smoking and alcohol.
The best course of action is to discuss your individual situation with your doctor. They can assess your specific needs and recommend the most appropriate treatment plan to help you achieve clearer, healthier skin and improve your overall well-being.

Tazaro gel: A Product of EGPI
EGPI, a leading pharmaceutical company founded in 2006, aims to expand its high-quality medicine production throughout the Middle East.
Company Overview
- Founded in 2006
- Sister company to Egyptian Group for Drug Trading (EGD), established in 1994
- Focuses on the Egyptian market with plans to expand in the Middle East
- Specializes in formulating, registering, and producing high-quality pharmaceutical products
Research, Development & Workforce
- Equipped with advanced technologies and extensive information resources
- Staffed by experienced pharmacists and chemists
- Maintains a portfolio of over 150 products across various therapeutic categories.
- Employs more than 450 dedicated employees.
- Operates 10 departments
Contact Information
- Location: El Mostakbal Square, El-Shabab St, El Obour City
- Tel: (+2) 02 43 13 03 21-30
- Fax: (+2) 02 43 13 03 24
- Website: https://egyptiangroup.net/
- Email: [email protected]
Dr. Ahmad Baker, PharmD
Senior Pharmacist & Health Educator
With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.
Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.

