Constipation is a common issue that affects many people at some point in their lives. While occasional constipation can be managed with lifestyle changes, chronic constipation may require medical intervention. One such intervention is the use of Purgaton, a medication designed to alleviate chronic constipation. In this blog post, we will delve into the details of Purgaton, its composition, pharmacological properties, indications, contraindications, drug interactions, precautions, and more. We will also address common questions and concerns related to Purgaton to provide you with a comprehensive understanding of this medication.

What is Purgaton?
Purgaton is a medication used to treat chronic constipation. It contains a purified extract of Senna, which is known for its laxative properties. The active ingredient in Purgaton is Calcium Sennosides, which are natural glycosides derived from the Senna plant. These glycosides help to increase colonic peristalsis, which is the movement of the colon that aids in the passage of fecal matter.
Composition of Purgaton
Each tablet of Purgaton contains:
- Purified extract of Senna equivalent to 20 mg Calcium Sennosides.
Pharmacological Properties
Purgaton works by increasing the speed of fecal matter passage in the cecum and ascending colon. It does this by reducing antiperistaltic waves, which results in decreased water absorption and the formation of soft stool. This action helps to alleviate constipation and promote regular bowel movements.
Indications for Use
Purgaton is primarily indicated for the treatment of:
- Atonic constipation: This type of constipation is characterized by a lack of muscle tone in the intestines, leading to slow bowel movements and difficulty passing stool.
Contraindications
While Purgaton is effective in treating chronic constipation, it is not suitable for everyone. It is contraindicated in the following conditions:
- Irritable colon
- Colitis
- Intestinal obstruction
- Appendicitis
- Acute intestinal inflammation
Drug Interactions
Purgaton can interact with several medications, including:
- Digitalis glycosides: Due to the potential for hypokalemia (low potassium levels).
- Antiarrhythmics: Medications used to treat irregular heart rhythms.
- Indomethacin: A nonsteroidal anti-inflammatory drug (NSAID).
- Nifedipine: A calcium channel blocker used to treat high blood pressure and angina.
- Estrogen: Hormones used in hormone replacement therapy and birth control pills.
Precautions
Long-term use of Purgaton can lead to several side effects, including:
- Hypokalemia: Low potassium levels in the blood.
- Hyperaldosteronism: Excessive production of the hormone aldosterone.
- Albuminuria: Presence of albumin in the urine.
- Hematuria: Presence of blood in the urine.
- Colonic atony: Loss of muscle tone in the colon.
- Melanosis coli: A benign condition characterized by dark pigmentation in the colon.
Pregnancy and Lactation
Purgaton should not be used during pregnancy or lactation. If you are pregnant or breastfeeding, consult your healthcare provider before taking Purgaton.
Method of Administration and Dosage
The recommended dosage for Purgaton is as follows:
- Adults: 2 tablets at bedtime.
- Children 6-12 years: 1 tablet at bedtime.
- Children 2-6 years: Half a tablet once daily.
- Children less than two years: Should not be used.
Packaging
Purgaton is available in the following packaging options:
- Boxes containing 30 tablets
- Boxes containing 200 tablets
- Boxes containing 1000 tablets
Important Reminders
- Always follow the doctor’s prescription and the instructions provided by your pharmacist.
- Do not interrupt the duration of treatment prescribed for you.
- Do not repeat taking the medication without instructions from the doctor.
- Keep medicines out of the reach of children.
Common Questions and Searches
What is considered chronic constipation?
Chronic constipation is defined as having fewer than three bowel movements per week for an extended period. It can be accompanied by symptoms such as straining during bowel movements, hard or lumpy stools, and a feeling of incomplete evacuation.
What are the main symptoms of chronic constipation?
The main symptoms of chronic constipation include:
- Infrequent bowel movements
- Straining during bowel movements
- Hard or lumpy stools
- A feeling of incomplete evacuation
- Abdominal pain or discomfort
- Bloating
Is chronic constipation genetic?
While genetics can play a role in some cases of chronic constipation, it is often the result of lifestyle factors such as a low-fiber diet, lack of physical activity, and inadequate fluid intake. Certain medical conditions and medications can also contribute to chronic constipation.
What are some natural ways to alleviate constipation?
Natural ways to alleviate constipation include:
- Increasing fiber intake through fruits, vegetables, and whole grains
- Drinking plenty of water
- Engaging in regular physical activity
- Establishing a regular bowel routine
- Avoiding foods that can cause constipation, such as processed foods and red meat
When should I see a doctor for chronic constipation?
You should see a doctor if:
- You have severe abdominal pain
- You have blood in your stool
- You have unexplained weight loss
- You have a sudden change in bowel habits
- You have constipation that does not improve with lifestyle changes or over-the-counter remedies
What are the dangers of untreated chronic constipation?
Untreated chronic constipation can lead to several complications, including:
- Hemorrhoids
- Anal fissures
- Fecal impaction
- Rectal prolapse
- Increased risk of colorectal cancer
How can I monitor my bowel movements at home?
You can monitor your bowel movements at home by:
- Keeping a bowel diary to track the frequency and consistency of your stools
- Paying attention to any changes in your bowel habits
- Noting any symptoms such as abdominal pain, bloating, or straining
What lifestyle changes are recommended for chronic constipation?
Lifestyle changes recommended for chronic constipation include:
- Increasing fiber intake
- Drinking plenty of water
- Engaging in regular physical activity
- Establishing a regular bowel routine
- Avoiding foods that can cause constipation
Does stress cause chronic constipation?
Stress can contribute to chronic constipation by affecting the digestive system. Chronic stress can lead to changes in bowel habits, including constipation. Managing stress through techniques such as meditation, yoga, and deep breathing exercises can help alleviate constipation.
What medications are used to treat chronic constipation?
Medications used to treat chronic constipation include:
- Laxatives: Such as Purgaton, which contains Senna extract.
- Stool softeners: Such as docusate sodium.
- Lubricants: Such as mineral oil.
- Osmotic agents: Such as polyethylene glycol.
- Stimulants: Such as bisacodyl.
Conclusion
Purgaton is a effective medication for treating chronic constipation. Its active ingredient, Calcium Sennosides, helps to increase colonic peristalsis and promote regular bowel movements. However, it is important to use Purgaton under the guidance of a healthcare provider and to be aware of its contraindications, drug interactions, and potential side effects. By following the recommended dosage and precautions, you can safely and effectively manage chronic constipation with Purgaton.
If you have any questions or concerns about Purgaton or chronic constipation, consult your healthcare provider for personalized advice and guidance.
Dr. Ahmad Baker, PharmD
Senior Pharmacist & Health Educator
With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.
Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.

