Inflacam (Piroxicam): A Guide to This NSAID for Chronic Joint Pain

✔️ Medically Reviewed by: Dr. Ahmad Baker, PharmD

Inflacam

A comprehensive guide to Inflacam (Piroxicam), a potent pain reliever and anti-inflammatory used to treat chronic joint and muscle pain.

Quick Facts

Active Ingredient
Piroxicam
Onset of Action
Within 30-60 minutes
With or Without Food
Must be taken with food
Important Warning
Risk to heart and stomach
Pregnancy & Lactation
Its use is prohibited
Storage
Room temperature

Definition and Uses

Inflacam is a drug belonging to the nonsteroidal anti-inflammatory drugs (NSAIDs) group, containing the active ingredient Piroxicam. It works by blocking the production of substances in the body called prostaglandins, which are responsible for causing pain, fever, and inflammation. Inflacam does not cure the underlying disease causing arthritis, but it is very effective at relieving symptoms as long as it is taken.

  • Treats symptoms of rheumatoid arthritis and osteoarthritis.
  • Relieves musculoskeletal pain from injuries like sprains and strains.
  • Alleviates menstrual pain (dysmenorrhea).
  • Treats ankylosing spondylitis (a form of arthritis that affects the spine joints).

How to Use and Dosage

The dose and pharmaceutical form of Inflacam depend on the condition being treated and its severity. It is essential to take the tablets or capsules with a meal or a glass of milk to reduce the risk of stomach irritation. The lowest effective dose should be used for the shortest possible duration as directed by a doctor.

  • Tablets and Capsules: The usual adult dose is 20 mg once daily.
  • Dispersible Tablets: Place in a little water until fully dissolved, then drink.
  • Intramuscular Injection: Administered by a healthcare professional for acute pain.
  • Suppositories: A dose of 20 mg once daily.

Side Effects

Like all NSAIDs, Inflacam can cause side effects, especially when taken in high doses or for long periods. The gastrointestinal system is the most affected. You should inform your doctor of any persistent or worrisome symptoms.

  • Common: Stomach upset, nausea, heartburn, indigestion, diarrhea or constipation, dizziness, and headache.
  • Less Common: High blood pressure, ringing in the ears, fluid retention, and swelling.
  • Serious: Stomach ulcer or bleeding (black stools, bloody vomit), increased risk of heart attack and stroke, kidney problems, severe skin reactions.

Warnings and Precautions

Inflacam, like other NSAIDs, carries important warnings regarding the cardiovascular and gastrointestinal systems. This drug should not be used without medical consultation, especially for patients with certain health conditions.

  • Cardiovascular Risk: Long-term use may increase the risk of a heart attack or stroke.
  • Stomach Risk: Increases the risk of ulceration, bleeding, and perforation of the stomach or intestines, which can be fatal.
  • Not for use before or after open-heart surgery.
  • Should be used with extreme caution in the elderly and patients with high blood pressure, kidney, or liver disease.
  • Should be avoided in the last trimester of pregnancy as it can harm the fetus.

Frequently Asked Questions

Why must Inflacam be taken with food?

NSAIDs like Inflacam work by inhibiting enzymes called COX, which reduces inflammation and pain. However, one of these enzymes (COX-1) is also responsible for protecting the stomach lining. Inhibiting this enzyme reduces the stomach’s protective layer, making it more vulnerable to damage from stomach acid.

Taking the medication with food or milk helps create a temporary barrier that reduces the drug’s direct contact with the stomach lining, thus lessening the risk of irritation, heartburn, and nausea. This simple step is very important for protecting your digestive system.

What is the difference between Inflacam capsules and injections?

The main difference lies in the method of action and effect. Capsules are taken orally and absorbed into the bloodstream to produce a systemic effect (throughout the body). This makes them suitable for long-term treatment of chronic pain, but they carry the risk of side effects on the stomach and heart.

Intramuscular injections, on the other hand, are administered by a healthcare professional and work faster and more potently. They are typically used to initiate treatment or to control acute and severe pain attacks, and are usually limited to a short period before switching to oral therapy.

Can I take Inflacam with paracetamol?

Yes, generally, it is safe to take Inflacam (Piroxicam) with paracetamol (acetaminophen). The two drugs work through completely different mechanisms to relieve pain. Inflacam is an anti-inflammatory, while paracetamol works mainly in the brain to relieve pain and reduce fever and has no significant anti-inflammatory effect.

This combination can be very effective for pain control. However, you should not take Inflacam with other NSAIDs (like ibuprofen or diclofenac) as this greatly increases the risk of stomach side effects. Always consult a pharmacist before combining any pain relievers.

How long can I use Inflacam safely?

The duration of treatment depends on the type and severity of pain. The general rule for NSAIDs is to use the lowest effective dose for the shortest possible time. For acute pain (like sports injuries), use for a few days may be sufficient. For chronic conditions (like arthritis), long-term use may be necessary.

Long-term use should always be under close medical supervision to monitor for potential side effects on blood pressure, kidneys, and the digestive system. Do not use Inflacam for a long period without consulting your doctor.

Does Inflacam raise blood pressure?

Yes, NSAIDs, including Inflacam, can cause an increase in blood pressure or worsen pre-existing high blood pressure. This happens because these drugs can affect kidney function and cause sodium and fluid retention in the body, which increases blood volume and thus raises pressure.

For this reason, patients with high blood pressure should use Inflacam with caution and under medical supervision. It is important to monitor blood pressure regularly during treatment. Inflacam may also reduce the effectiveness of some blood pressure medications.

What are the signs of stomach bleeding I should watch for?

Stomach bleeding is one of the most serious side effects of NSAIDs. It is very important to know the warning signs and seek medical help immediately if they appear. There may not always be pain, so attention should be paid to other changes.

Key signs include: black or tarry-looking stools, vomit that looks like coffee grounds or contains red blood, severe and persistent stomach pain, feeling dizzy or faint, and pale skin. These symptoms constitute a medical emergency.

Can older adults use Inflacam?

Inflacam should be used with extreme caution in the elderly. People over 65 are significantly more susceptible to the serious side effects of NSAIDs, especially stomach bleeding, kidney problems, high blood pressure, and heart problems.

Doctors usually prescribe the lowest possible dose for the shortest necessary period for older adults. If long-term treatment is necessary, the doctor will monitor the patient closely. Safer options may be available and should be discussed with the doctor.

What should I do if I miss a dose?

If you forget to take your dose, take it as soon as you remember, as long as it is not close to the time of your next dose. If it is almost time for the next dose, skip the missed dose and take the next one at its usual time. Do not take a double dose to make up for the missed one.

Since Inflacam is usually taken once a day, it is relatively easy to remember. Try to link the dose time to a consistent daily activity, such as always taking it with your evening meal, to help maintain regularity.

Can Inflacam be used for menstrual pain?

Yes, Inflacam can be very effective in relieving menstrual pain (dysmenorrhea). This pain is caused by the release of large amounts of prostaglandins in the uterus, which cause painful contractions. Inflacam works by blocking the production of these substances, thereby reducing the contractions and the associated pain.

For best results, it is advisable to start taking the medication at the onset of pain or a day before the start of the menstrual period, and continue for two to three days. However, it should not be used by women who are planning to become pregnant.

Can I drink alcohol while on treatment with Inflacam?

It is advised to avoid or severely limit alcohol consumption while taking Inflacam or any other NSAID. Both alcohol and these drugs can irritate the stomach lining. Taking them together significantly increases the risk of stomach bleeding or ulcers.

If you are taking Inflacam, it is best to avoid alcohol completely to protect your digestive system. If you must drink, discuss it with your doctor to determine if it is safe for you and what moderate amount might be tolerated.

Disclaimer and Information Sources

  • Purpose of Content: The information provided in this guide is for awareness and knowledge purposes only, and is not a substitute for professional medical advice. Do not use this or any other medication without consulting your doctor or pharmacist.
  • Source of Information: This content has been prepared based on official, documented medical sources appropriate for the topic (such as official drug leaflets, health ministry guidelines, FDA directives, or specialized medical organizations).
  • Publication Date | Last Updated: [October 2025]
Box of Inflacam 15 mg Meloxicam capsules, an anti-inflammatory and analgesic.
Inflacam 15 mg Meloxicam capsules, used to relieve inflammation associated with rheumatic and joint diseases.
Dr. Ahmad Baker

Dr. Ahmad Baker, PharmD

Senior Pharmacist & Health Educator

With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.

Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.