Composition
Each tablet contains: Secnidazole: 500 mg.
Properties
Secnidazole is a 5-nitroimidazole derivative. It has antiparasitic activity against Entameba histolytica, Trichomonas vaginalis and Giardia lamblia.
Pharmacokinetics
Secnidazole is readily absorbed after administration by mouth. Peak plasma concentrations are achieved within 3 hours after a single oral dose of 2 gm (4 tablets). It is mainly eliminated in urine. Plasma half-life is about 24 hours.
Indications
- Intestinal amebiasis Hepatic amebiasis
- Urogenital trichomoniasis Giardiasis
Contraindications
- History of hypersensitivity to imidazole derivatives
- Pregnancy or lactation
Side Effects
Occasionally, it may cause some G.I.T. disorders, e.g. nausea, vomiting, abdominal cramps and an unpleasant metallic taste. In rare cases, moderate leucopenia may occur which disappears after treatment discontinuation.
Dosage
Acute intestinal amebiasis: 1-day treatment
- Adults: 2 gm (4 tablets) as a single dose.
- Children: 30 mg/kg in a single dose.
Chronic intestinal amebiasis (cystic form): 3-day treatment
- Adults: 2 gm (4 tablets) in a single daily dose for 3 days.
- Children: 30 mg/kg in a single daily dose for 3 days.
Hepatic amebiasis: 5-day treatment
- Adults: 1.5 gm (3 tablets) in a single daily dose for 5 days
- Children: 30 mg/kg in single daily dose for 5 days.
Urogenital trichomoniasis: 1-day treatment
- Adults: 2 gm (4 tablets) as a single dose.
Giardiasis: 1-day treatment
- Adults: 2 gm (4 tablets) as a single dose.
- Children: 30 mg/kg in a single dose.
How Supplied
Strips of 4 tablets in a packs of 1 strip.
Keep all medicaments out of reach of children
Product of: AMOUN PHARMACEUTICAL CO. El-Obour City, Cairo, Egypt. ATC Code: P01AB07
Dr. Ahmad Baker, PharmD
Senior Pharmacist & Health Educator
With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.
Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.