Etaphylline Suppository is a bronchodilator medication used to manage and relieve symptoms of obstructive airway diseases, such as asthma, chronic bronchitis, and emphysema. Each suppository contains Acepifylline [a derivative of theophylline, a drug that helps relax muscles around the airways in the lungs, making breathing easier]. This medication is ideal for patients who require an alternative to oral bronchodilators or who have difficulty using inhalers. Understanding how to use Etaphylline Suppository correctly, its benefits, and its precautions is essential for achieving optimal results in respiratory management.
Active Ingredients
Acepifylline (Acefylline Piperazine) 350 mg
Acepifylline is a theophylline derivative [a class of drugs used to open up the airways in the lungs by relaxing smooth muscles], known for its bronchodilator properties. It is often used in treating conditions that cause breathing difficulties due to narrowing or obstruction of the airways. Acepifylline works by relaxing the bronchial muscles, relieving bronchospasm [sudden constriction of the muscles in the walls of the airways in the lungs], and improving airflow.
Indications for Use
Etaphylline Suppository is indicated for the treatment of obstructive airway diseases, including:
- Asthma [a chronic disease where the airways narrow and swell, causing difficulty breathing]
- Chronic bronchitis [a long-term inflammation of the airways in the lungs, leading to coughing and mucus production]
- Emphysema [a lung condition where the air sacs (alveoli) are damaged, reducing the surface area for gas exchange]
Benefits:
- Bronchodilation: Etaphylline Suppository helps relax the airways, making it easier for patients with obstructive airway diseases to breathe.
- Alternative administration: As a suppository, it is useful for patients who may not tolerate oral medications or those who struggle with inhalers.
- Convenience: This form provides consistent absorption and is ideal for patients who have difficulty swallowing tablets or using inhalers due to acute breathing problems.

Dosage and Duration of Use
Recommended Dosage:
- Adults: 1 to 3 suppositories daily, or as prescribed by a physician.
- Administration: The suppository should be inserted rectally, as directed by your healthcare provider.
It is essential to follow the physician’s prescribed dosage to avoid complications or side effects.
Duration:
The duration of treatment depends on the severity of the condition and the patient’s response to the medication. It is essential to consult a healthcare professional for personalized advice.
Warnings and Precautions
Side Effects:
While Etaphylline Suppository is generally well-tolerated, some patients may experience side effects, including:
- Nausea [a feeling of sickness with an inclination to vomit]
- Vomiting
- Insomnia [difficulty falling asleep or staying asleep]
- Headache
- Palpitations [feeling of a rapid, fluttering, or pounding heart]
These side effects are usually mild, but if they persist or worsen, it’s important to contact your healthcare provider.
Precautions:
- Cardiac conditions: Etaphylline should be administered with caution in elderly patients and those with pre-existing heart conditions, as it may exacerbate cardiac issues.
- Liver disease: Patients with liver disease should use this medication cautiously, as impaired liver function may affect drug metabolism and increase the risk of side effects.
- Drug interactions: Avoid using this suppository alongside other xanthine medications [a class of drugs, including theophylline, that have similar bronchodilating effects] to prevent toxicity.
Pregnancy and Lactation:
There is limited data available on the safety of Etaphylline Suppository during pregnancy and lactation. Therefore, it is essential to use this medication only under the guidance of a healthcare professional during these periods.
Price and Product Information
Pricing:
Etaphylline Suppository is available in Egypt for 13.5 L.E. per box, which contains 10 suppositories.
Packaging and Availability:
Etaphylline is packaged in a box of 10 suppositories and can be purchased from pharmacies throughout Egypt.
Conclusion
Etaphylline Suppository is an effective bronchodilator, providing relief for patients with obstructive airway diseases like asthma, chronic bronchitis, and emphysema. With its convenient administration form, it offers an alternative to oral medications or inhalers, especially for patients who struggle with traditional forms of treatment. However, it is crucial to use this medication as directed by a healthcare provider, keeping in mind any potential side effects and precautions.
For individuals suffering from chronic respiratory conditions, Etaphylline Suppository can be a valuable tool in improving breathing and enhancing quality of life.
Etaphylline Suppository is produced by Memphis Pharmaceutical Industries, an Egyptian company that distributes and exports its products to various countries in Africa and the Middle East.
Dr. Ahmad Baker, PharmD
Senior Pharmacist & Health Educator
With over 23 years of clinical experience in hospital and community pharmacy across Egypt and Saudi Arabia, Dr. Ahmad specializes in reproductive health and pharmaceutical safety. He is dedicated to providing evidence-based guidance to empower patients in the MENA region.
Medical Disclaimer: This content is for educational purposes and reflects the latest pharmaceutical protocols. It is not a substitute for personal medical advice. Always consult Dr. Ahmad Baker or your healthcare provider before starting any treatment.

