BUCCAZOLE ORAL GEL to prevent and treat fungal infections of oropharyngeal

BUCCAZOLE ORAL GEL is a highly effective topical formulation specifically formulated to prevent and treat fungal infections of oropharyngeal [relating to the mouth and pharynx] mucosa particularly oral candidiasis (thrush) [a fungal infection of the mouth and throat caused by Candida yeast].

Composition

Each 100 g contains: Miconazole (base) 2 g

Properties

BUCCAZOLE (miconazole) ORAL GEL is a highly effective topical formulation specifically formulated to prevent and treat fungal infections of oropharyngeal [relating to the mouth and pharynx] mucosa particularly oral candidiasis (thrush) [a fungal infection of the mouth and throat caused by Candida yeast]. BUCCAZOLE ORAL GEL possesses a broad spectrum activity against pathogenic [disease-causing] fungi and Gram-positive bacteria [a type of bacteria that retains the Gram stain in laboratory testing] including Staphylococci [a genus of bacteria that can cause a variety of infections] and Streptococci [a genus of bacteria that can cause a variety of infections] species. Miconazole interferes with ergosterol synthesis [a crucial component of fungal cell membranes] of fungal cell membrane and alters its permeability resulting in leakage of the vital constituents from fungal cells with eventual cell death. BUCCAZOLE ORAL GEL is poorly absorbed from mucosa [the mucous membrane lining body cavities and canals], thus it ensures high local concentration at the affected area with rapid relief of the manifestations of local fungal infections. BUCCAZOLE ORAL GEL produces clinical and mycological [relating to the study of fungi] cure without causing the side effects commonly encountered with systemic antifungal medications. BUCCAZOLE ORAL GEL is safe, well tolerated and palatable, and is the drug of choice for use in infants, children, adults and the elderly.

Indications

• Oral candidiasis (thrush) [a fungal infection of the mouth and throat caused by Candida yeast].
• Denture stomatitis [inflammation of the oral mucosa under a denture].
• Pharyngoesophageal candidiasis [fungal infection of the pharynx and esophagus]
• Patients at high risk of fungal infections, as prophylactic [preventative] therapy in cases of:
  • Immunocompromised patients [individuals with weakened immune systems].
  • Diabetics.
  • Patients under therapy with corticosteroid [a type of anti-inflammatory drug], broad spectrum antibiotic [an antibiotic effective against a wide range of bacteria] or immunosuppressant [a drug that suppresses the immune system].

Dosage

The gel is applied gently on the affected area after meals.

• Infants and children below 2 years: 2.5 ml (half teaspoonful) two times daily.
• Children from 2-6 years: 5 ml (1 teaspoonful) two times daily.
• Children from 6-12 years: 5 ml (1 teaspoonful) 4 times daily.
• Adults: 5-10 ml (1-2 teaspoonfuls) 4 times daily.

N.B.

• For localized lesions of the mouth, a small amount of the gel is to be applied directly to the affected area, with a clean finger, two to four times a day.
• The gel must be retained in the mouth in contact with the affected area as long as possible before swallowing.
• Treatment is continued for 48 hours after disappearance of symptoms.

Contraindications

Hypersensitivity to miconazole [allergy to miconazole].

Precautions

Dental prosthesis [artificial teeth] should be removed every night and brushed with the gel during the course of treatment from oral candidiasis [a fungal infection of the mouth and throat caused by Candida yeast].

Side effects

BUCCAZOLE ORAL GEL is safe and well tolerated. Nausea might occur rarely.

Pregnancy and lactation:

No harmful effects have been reported following the use of miconazole-containing oral gels. However, it is better to use miconazole-containing oral gels during pregnancy and lactation under medical supervision.

Drug interactions:

None reported with miconazole-containing oral gels.

Overdosage and treatment

Accidental ingestion of high doses may result in vomiting and diarrhea [frequent bowel movements that are loose and watery]. Treatment is symptomatic [treating the symptoms without addressing the underlying cause] and supportive.

Packing

A tube containing 20 g.

Storage

Keep at temperature (15-30°C) [59-86°F]. Keep out of the reach of children.

Latest Information

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Disclaimer

THIS MEDICAMENT is a product which affects your health and its consumption contrary to instructions is dangerous for you. -Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sold the medicament. -The doctor and the pharmacist are the experts in medicines, their benefits and risks. -Do not by yourself interrupt the period of treatment prescribed. -Do not repeat the same prescription without consulting your doctor -Keep all medicaments out of reach of children. Council of Arab Health Ministers, Union of Arab Pharmacists.

Conclusion

BUCCAZOLE Oral Gel provides a safe and effective treatment for oral fungal and bacterial infections. Always follow the instructions provided and consult with a healthcare professional for any concerns.