Alphintern – Anti-inflammatory and anti-edematous

Alphintern® has a synergistic, anti-inflammatory and anti-edematous action of two potent proteolytic enzymes affecting the exudative phase of inflammation and ensuring the destruction of peptide chains in inflammatory processes regardless of the origin.

The gastro-resistant and entero-soluble coating of Alphintern tablets ensures the best tolerability, as well as, the best efficiency due to its absorption in the intestine only.

Indications

• Reduction and resorption of Edema and exudates.
• Adjunctive therapy in inflammatory conditions.

Contra-Indications

• Known hypersensitivity to Trypsin or Chymotrypsin.
• In patients with congenital or acquired bleeding disorders, including hemophilia.
• In patients with severe liver and / or kidney damage.
• Immediately prior to a surgical procedure in patients.

Composition

Each Enteric Coated tablet contains:

Active Ingredients: Trypsin-Chymotrypsin mix 12 mg Eq. to:

• 14 μ katal alpha Chymotrypsin
• 5 μ katal Trypsin

Dosage & Administration

One to two tablets 3 times daily to be swallowed (not chewed) or as prescribed by the physician.

Special Warnings and Precautions for Use

Children and adolescents: There is no experience in children and adolescents under 18 years in these indications.

Adults: Before surgery the fibrinolytic activity of the preparation should be considered and the patient should be monitored accordingly. The drug should be discontinued in any case, 4 days before the operation.

If allergic reaction occur, therapy should be discontinued. In individual cases: Allergic reactions up to anaphylactic shock may come.

There are insufficient experience in pregnancy and lactation so
it is not recommended to be used.

Concomitant use of anticoagulants and/ or antiplatelet agents: May only be used after careful consideration of the benefit/risk ratio, and under strict supervision of the physician.

Adverse effects

It can cause bloating, flatulence, change of stool texture, color and smell.

There have been occasional reports of asthma, and rarely of allergic reactions.

Gastrointestinal side effects can usually be resolved by distributing the dose throughout the day.

Storage conditions

• Store at temperature not exceeding 25 °C, In dry place.
• Shelf Life: 2 years.

How supplied

Carton Box containing 1,2,3 (AL/Colorless transparent PVC/PVDC) Strips each of 10 Enteric coated tablet + Insert leaflet.

Keep all medicaments out of reach of children

Product of: AMOUN PHARMACEUTICAL CO. El-Obour City, Cairo, Egypt. ATC Code: S01KX01, B06AA04, M09AB52