ZYTIGA: Your Guide to Prostate Cancer Medication

Prostate cancer is a widespread concern among adult men, especially when it has extended to other parts of the body. In such cases, a medication known as ZYTIGA, containing abiraterone acetate, plays a crucial role in the treatment process. This article provides valuable information for those who have been prescribed ZYTIGA or are curious about its application.

What Is ZYTIGA and Its Purpose?

ZYTIGA primarily consists of abiraterone acetate and is specifically designed to address prostate cancer in adult men with advanced stages of the disease. This medication works by inhibiting the production of testosterone in the body, effectively slowing down the progression of prostate cancer.

For patients who are in the early stages of the disease and are still responsive to hormone therapy, ZYTIGA is administered in conjunction with treatment that reduces testosterone levels (androgen deprivation therapy). Additionally, when prescribed ZYTIGA, your doctor will also recommend another medication, either prednisone or prednisolone, to minimize the risk of high blood pressure, excess fluid retention, or potassium level reduction in the blood.

Precautions and Warnings

Before initiating ZYTIGA treatment, certain precautions and warnings must be considered:

  • If you are allergic to abiraterone acetate or any of the ingredients in this medication, you should not take ZYTIGA.
  • ZYTIGA is strictly for use by male patients, and it should not be used by women, especially if they are pregnant.
  • Severe liver damage contraindicates the use of ZYTIGA.

It’s crucial to consult your doctor or pharmacist before starting this treatment, especially if you:

  • Have liver problems.
  • Have been diagnosed with high blood pressure, heart failure, low blood potassium, or any heart or blood vessel issues.
  • Experience an irregular or rapid heart rate, shortness of breath, rapid weight gain, or swelling in the feet, ankles, or legs.
  • Have previously used ketoconazole for prostate cancer.
  • Have concerns about the impact of this medication on your bones.
  • Have high blood sugar.

Your doctor should also be informed if you have any heart or blood vessel conditions, including heart rhythm problems, or if you are taking medicines for these conditions. Notify your doctor if you notice any signs of liver problems, such as yellowing of the skin or eyes, dark urine, severe nausea, or vomiting. In some rare cases, acute liver failure may occur, which can be life-threatening.

Monitoring Blood Levels

While taking ZYTIGA, regular blood tests are essential to monitor liver function. It’s noteworthy that the effects on your liver may not present noticeable symptoms.

Interaction with Other Medications

Before taking any other medication alongside ZYTIGA, consult your doctor or pharmacist for advice. Inform them about any medicines you are currently taking or have recently taken. ZYTIGA may interact with various medications, affecting their efficacy. Your doctor may need to adjust the dosages of these medicines accordingly. Furthermore, some drugs can influence the effects of ZYTIGA, potentially causing side effects or reducing its effectiveness.


It’s crucial to follow the prescribed instructions when taking ZYTIGA:

  • The recommended dose is four tablets (1,000 mg) once a day.
  • ZYTIGA should be taken by mouth without food.
  • After taking ZYTIGA, wait at least two hours before eating, and do not eat anything for at least one hour after taking the medication.
  • Swallow the tablets whole with water, without breaking them.
  • ZYTIGA is usually taken in conjunction with prednisone or prednisolone. Follow your doctor’s instructions for these medications, and do not stop taking them unless advised by your doctor.

Possible Side Effects

As with any medication, ZYTIGA can cause side effects, although not everyone will experience them. Some common side effects may include fluid retention in the legs or feet, low blood potassium, increases in liver function test results, high blood pressure, urinary tract infections, and diarrhea.

Less frequently, patients may experience high fat levels in the blood, chest pain, irregular heartbeats, heart failure, rapid heart rate, severe infections, bone fractures, indigestion, or blood in the urine. In rare instances, issues related to the adrenal glands, abnormal heart rhythms, muscle weakness, or muscle pain may arise. Lung irritation and acute liver failure are even rarer side effects.

If you experience muscle weakness, muscle twitches, or palpitations, it could be an indication of low blood potassium levels. Always discuss any side effects with your doctor or pharmacist. By reporting side effects, you can contribute to the safety evaluation of this medication.

Storing ZYTIGA

To ensure the safety and effectiveness of ZYTIGA:

  • Keep it out of the reach of children.
  • Do not use it after the expiry date.
  • Store below 30°C.
  • Dispose of any unused medication correctly, following your pharmacist’s guidance.

In Conclusion

ZYTIGA is a valuable medication in the fight against advanced prostate cancer in men. When used correctly, under the supervision of your doctor, it can help slow the progression of the disease. Always consult your healthcare provider if you have questions or concerns regarding its use or any potential side effects. Your health and well-being are of paramount importance.

زيتيجا: الدواء الفعّال لعلاج سرطان البروستاتا في الرجال