Your Guide to ALPHAGAN® Purite®: Your Eye Health Companion

When it comes to your eye health, understanding your medication is crucial. Let’s delve into the patient information leaflet for ALPHAGAN® Purite®, an ophthalmic solution that plays a significant role in maintaining eye pressure. We aim to simplify the information for you in a professional and straightforward manner.

1. Scheduling Status

  • Schedule 3: This classification ensures that you’ll need a prescription from a healthcare professional to obtain ALPHAGAN® Purite®.

2. What ALPHAGAN® Purite® Contains

ALPHAGAN® Purite® contains the following components:

  • Active Substance: Brimonidine Tartrate
  • Other Ingredients: These include boric acid, calcium chloride, magnesium chloride, potassium chloride, purified water, sodium borate, sodium carboxymethylcellulose, sodium chloride, and Purite® (stabilized oxychloro complex) 0.005% m/v, which acts as a preservative.

3. What ALPHAGAN® Purite® Is Used For

ALPHAGAN® Purite® ophthalmic solution serves a vital purpose for your eye health:

  • It facilitates fluid drainage from the eye chamber.
  • Simultaneously, it reduces the production of eye fluid, effectively lowering eye pressure.
  • ALPHAGAN® Purite® is prescribed for treating high eye pressure in conditions like glaucoma and ocular hypertension. It can be used either alone or alongside another eye drop designed to reduce eye pressure.

4. Before You Use ALPHAGAN® Purite®

There are several considerations and precautions to keep in mind:

  • Hypersensitivity: Do not use ALPHAGAN® Purite® if you are allergic to brimonidine tartrate or any of the ingredients in the solution.
  • Age Restrictions: This medication should not be used in neonates and infants under the age of 2 years.
  • Special Care: Consult your healthcare provider if you have any heart-related conditions, kidney or liver issues, a history of depression, or low blood pressure. Certain conditions like Raynaud’s phenomenon, which causes discolouration of fingers and toes after temperature changes or emotional events, should be discussed with your doctor.
  • Surgeries: If you are scheduled for surgery requiring general anesthesia, or if you are currently on monoamine oxidase (MAO) inhibitors, caution is needed.

Pregnancy and Breastfeeding

The use of ALPHAGAN® Purite® during pregnancy and breastfeeding is not well established. Therefore, consult your healthcare provider for guidance if you are pregnant or nursing.

Driving and Using Machinery

Be cautious when driving or operating machinery if you’ve just used ALPHAGAN® Purite®. It may cause drowsiness or blurred vision. Ensure these symptoms have subsided before resuming such activities.

Using Other Medicines with ALPHAGAN® Purite®

Always inform your healthcare provider about any other medications you are taking, including complementary or traditional remedies. The following medications require extra caution:

  • Medications for high blood pressure
  • Digoxin, used for heart conditions
  • Beta-blockers (both ophthalmic and systemic)
  • Tricyclic antidepressants
  • Monoamine oxidase (MAO) inhibitors for depression
  • Alcohol, nervous system depressants, opiates, sedatives, or anesthetics

5. How to Use ALPHAGAN® Purite®

  • Use ALPHAGAN® Purite® exactly as your doctor instructs.
  • The usual dose is one drop in the eye(s) every twelve hours.
  • To apply the drops, tilt your head back, gently pull down the lower eyelid, and squeeze one drop into the eye. Avoid touching the eye, eyelids, or lashes with the dropper.
  • Close your eyes, blink to distribute the drops, and gently press on the inner corners of your eye.
  • Replace the dropper cap.
  • Continue using ALPHAGAN® Purite® even if you feel well unless your doctor advises otherwise.

Use in Children

  • ALPHAGAN® Purite® should not be used in children under the age of 2 years.
  • Children aged 2 years and above, or weighing less than or equal to 20 kg, should be treated with caution.

Things to Be Careful of

  • Always store the eye drops below 25°C and protect them from light.
  • Keep eye drops out of reach of children.
  • Dispose of any unused drops 30 days after opening the bottle.
  • Do not touch the dropper tip to any surface to avoid contamination.
  • Tell your doctor immediately if you develop an eye infection, injure your eye, or need an eye operation.

6. Possible Side Effects

ALPHAGAN® Purite® may have side effects. Common side effects include high cholesterol levels, dizziness, headache, and various eye-related symptoms like redness and itching. If you notice any side effects, consult your healthcare provider for advice.

7. Storing and Disposing of ALPHAGAN® Purite®

  • Store ALPHAGAN® Purite® at or below 25°C.
  • Protect it from light.
  • Keep it out of children’s reach.
  • Dispose of the solution properly, following your pharmacist’s guidance.
  • Do not put the eye drops in the freezer.

8. Presentation of ALPHAGAN® Purite®

ALPHAGAN® Purite® is supplied in sterile, opaque teal plastic bottles and tips with purple caps, containing 5 ml of solution.

9. Identification of ALPHAGAN® Purite®

The solution is a clear green-yellow liquid, free of visible particulate matter.

10. Registration Number

The registration number for ALPHAGAN® Purite® is A39/15.4/0202.

11. Name and Address of Registration Holder

Allergan Pharmaceuticals (Pty) Ltd 30 New Road (entrance off Bavaria Road) Randjespark Ext. 11, Midrand, 1682 Johannesburg, Gauteng South Africa Telephone number: (011) 545 6600

Your eye health is paramount. By understanding your medication and following your healthcare provider’s advice, you can ensure that ALPHAGAN® Purite® helps you maintain healthy eye pressure and overall well-being.