XATRAL LP 10 mg: A Comprehensive Guide

Are you or a loved one prescribed XATRAL LP 10 mg (alfuzosin)? This medication belongs to a group known as alpha-blockers and has several important therapeutic uses. This article will guide you through its indications, dosage, and other relevant information.


XATRAL LP 10 mg is prescribed primarily for the treatment of benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges, causing various urinary problems in men. This medication can be used to:

  • Relieve difficulties in urination caused by an enlarged prostate.
  • Assist in urinary drainage by using a catheter when it’s impossible to urinate.

It’s essential to note that XATRAL LP 10 mg is exclusively intended for men.

What You Should Know Before Taking XATRAL LP 10 mg


Before using XATRAL LP 10 mg, you should be aware of certain contraindications:

  • If you are allergic to alfuzosin or any other component in XATRAL LP 10 mg.
  • If you suffer from orthostatic hypotension, a condition where your blood pressure drops when you stand up, potentially leading to dizziness and fainting.
  • If you have severe liver disease (hepatic insufficiency) or severe kidney disease (severe renal insufficiency).
  • If you are taking specific medications used in the treatment of HIV (e.g., protease inhibitors with ritonavir or cobicistat), hepatitis C (e.g., telaprevir or boceprevir), certain antifungal medications (e.g., ketoconazole, itraconazole, posaconazole), or specific antibacterial medications (e.g., clarithromycin, erythromycin, telithromycin). Please refer to the “Taking or Using Other Medications” section.


Take the following precautions when using XATRAL LP 10 mg:

  • Inform your doctor if you have any heart conditions, particularly angina, acute heart failure, or irregular heart rhythms. Mention if you’ve previously experienced significant drops in blood pressure while using other alpha-blockers.
  • You may experience orthostatic hypotension, characterized by a sudden drop in blood pressure when standing up, resulting in dizziness, fatigue, and sweating. In such cases, lie down until these temporary effects subside and consult your doctor.
  • Special care should be taken in elderly individuals and those who are concurrently taking medications for high blood pressure or nitrate derivatives used for angina. Avoid using this medication with certain high blood pressure medications (antihypertensives like doxazosin, prazosin, and urapidil). For further information, see the “Be Cautious with XATRAL LP 10 mg” section.

Other Medications

It is vital to avoid combining XATRAL LP 10 mg with specific medications as mentioned earlier, such as HIV, hepatitis C, antifungal, and antibacterial drugs. Always inform your doctor about any medication you are taking or have recently taken, including over-the-counter drugs.

Pregnancy and Breastfeeding

XATRAL LP 10 mg is not intended for use in women.

Driving and Operating Machinery

Exercise caution when driving or operating machinery while using this medication. It can lead to a significant drop in blood pressure when standing up, causing dizziness, fatigue, or visual disturbances, especially at the beginning of treatment.

Important Information Regarding XATRAL LP 10 mg Components

This medication contains castor oil, which can lead to mild digestive disturbances, including a mild laxative effect and diarrhea. Be cautious if you have a known sensitivity to castor oil.

How to Take XATRAL LP 10 mg


The typical dose is one tablet daily, taken immediately after the evening meal. Your doctor will specify the duration of treatment based on your condition. Always adhere to the prescribed dosage, and consult your doctor or pharmacist if you have any uncertainties.


Swallow the tablet whole with a glass of water. The tablets are extended-release, which means the active ingredient is gradually released in the body. To ensure the medication maintains its efficacy, do not crush, chew, or break the tablets into powder.


XATRAL LP 10 mg is not suitable for use in children aged 2 to 16 years.

Missed Dose

If you forget to take a dose of XATRAL LP 10 mg, do not take a double dose to compensate for the missed one.

Possible Side Effects

As with any medication, XATRAL LP 10 mg can cause side effects, although not everyone experiences them. Common side effects include:

  • Dizziness
  • Vertigo
  • Discomfort
  • Headache
  • Nausea
  • Abdominal pain
  • Fatigue

Less common side effects encompass:

  • Fainting (sudden loss of consciousness)
  • A drop in blood pressure when moving from a lying to standing position
  • Accelerated heart rate
  • Palpitations
  • Diarrhea
  • Dry mouth
  • Nasal congestion or a runny nose (rhinitis)
  • Skin rashes or itching
  • Edema (swelling)
  • Chest pain
  • Facial redness

Very rare side effects may include:

  • Chest pain in patients with coronary disorders
  • Hives
  • Sudden swelling of an organ, face, and/or neck, which may cause breathing difficulty (angioedema)
  • Liver diseases (hepatitis), often due to bile duct blockage
  • Painful and prolonged erections
  • Flaccid pupil during cataract surgery
  • Irregular heartbeat (atrial fibrillation)
  • Vomiting
  • Reduced white blood cell count (neutropenia)

If you experience any side effects, including those not mentioned here, inform your doctor or pharmacist. Reporting side effects helps improve the safety of the medication.

How to Store XATRAL LP 10 mg

Do not use XATRAL LP 10 mg after the expiration date indicated on the packaging. Store it at a temperature not exceeding 30°C. Dispose of any unused medication responsibly to protect the environment and keep it out of reach of children.

Additional Information


  • Active ingredient: Alfuzosin hydrochloride 10 mg per tablet
  • Excipients: Hypromellose, hydrogenated castor oil, ethylcellulose, yellow iron oxide (E172), hydrated colloidal silica, magnesium stearate, mannitol, povidone, microcrystalline cellulose.

Presentation and Packaging

XATRAL LP 10 mg is available as extended-release tablets and is typically sold in boxes containing 30 tablets. Please note that not all presentations may be available in your country.

Prescription and Dispensing

XATRAL LP 10 mg is a prescription-only medication.

In conclusion, if you or someone you know is prescribed XATRAL LP 10 mg, it’s essential to understand its indications, precautions, and proper usage. Consult with your healthcare provider for personalized advice and to address any concerns related to this medication.