Understanding Your Medication: CARDEXIN 0.25 (DIGOXIN TABLETS BP 0.25 mg)

Are you taking CARDEXIN 0.25 tablets? If so, it’s important to be well-informed about this medication, what it’s used for, how to take it, and potential side effects. In this guide, we’ll provide you with a comprehensive understanding of CARDEXIN 0.25, ensuring you use it safely and effectively.

1. What Are CARDEXIN 0.25 Tablets and Their Uses

CARDEXIN 0.25 is a medication that falls under the group of medicines known as cardiac glycosides. These tablets help regulate your heart’s rhythm and improve its overall efficiency. The two main uses of CARDEXIN 0.25 tablets are:

  • Heart Failure: They are prescribed to individuals experiencing heart failure, a condition where the heart is unable to pump blood effectively, leading to symptoms like shortness of breath and fatigue.
  • Irregular Heartbeats or Heart Rhythm: CARDEXIN 0.25 can also be used to address irregular heartbeats, ensuring your heart maintains a steady rhythm.

2. Important Considerations Before Taking CARDEXIN 0.25 Tablets

Before you start using CARDEXIN 0.25, there are some crucial factors to be aware of. You should not take these tablets if:

  • You are allergic to Digoxin tablets or related medications like digitoxin, or any of the tablet’s ingredients. Allergic reactions can include skin rashes, itching, difficulty breathing, or swelling of your face, lips, throat, or tongue.

If your doctor has recently prescribed CARDEXIN 0.25, let them know if you’ve taken any cardiac glycosides (like digoxin or digitoxin) within the past two weeks.

Moreover, CARDEXIN 0.25 tablets should not be taken if you have certain heart issues such as:

  • Inflammation of the heart
  • Enlargement of the heart muscle
  • Problems in the conduction of electrical impulses in the heart
  • Irregular heartbeats, including Wolff-Parkinson-White syndrome

While these tablets are used to treat severe heart problems, they may exacerbate other heart issues. If you have any of these conditions, consult with your healthcare provider.

It’s essential to check with your doctor or pharmacist if you:

  • Have significant lung or breathing disorders
  • Have been informed that you have low blood potassium, low magnesium levels, or high blood calcium levels
  • Have recently experienced a heart attack
  • Suffer from stomach or bowel problems
  • Deal with abnormal heart rhythms
  • Have congestive heart failure or other heart problems such as cardiac amyloidosis, myocarditis, or constrictive pericarditis
  • Have Beri-beri disease
  • Are going to have a heart test called an electrocardiogram (ECG)
  • Have a thyroid condition
  • Have malabsorption syndrome
  • Have a sinoatrial disorder, such as Sick Sinus Syndrome

Additionally, if you’re taking other medications, make sure to inform your doctor or pharmacist, especially if you’re using any of the following:

  • The herbal remedy St. John’s Wort
  • Medications for high blood pressure
  • Drugs to treat irregular heart rhythms
  • Medications for heart conditions
  • Ranolazine for angina
  • Medications for allergic reactions, shock, or heart attacks
  • Ticagrelor to prevent blood clots
  • Medications to lower cholesterol
  • Drugs to treat arthritis
  • Kaolin for stomach upsets, laxatives, metoclopramide for nausea
  • Medications to treat infections
  • Medications to treat HIV
  • Telaprevir to treat hepatitis C
  • Antidepressants like nefazodone, trazodone, and lithium
  • Drugs for diabetes (acarbose)
  • Antiepileptic medications (phenytoin and topiramate)
  • Quinine for malaria or night-time leg cramps
  • Calcium salts and vitamin D
  • Carbimazole for hyperthyroidism
  • Cyclosporine to reduce organ transplant rejection
  • Corticosteroids (prednisolone and hydrocortisone)
  • Cancer treatment drugs (lapatinib)
  • Muscle relaxants (propantheline, edrophonium, suxamethonium, pancuronium, or tizanidine)
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for pain
  • Asthma medication (salbutamol)
  • Medications for stomach ulcers (carbenoxolone, omeprazole, pantoprazole, rabeprazole, sucralfate)
  • Drugs for kidney disease (tolvaptan and conivaptan)
  • Bupropion to aid smoking cessation
  • Nutritional supplements administered through a tube

3. How to Take CARDEXIN 0.25 Tablets

For CARDEXIN 0.25 tablets to be effective and safe, it’s vital to adhere to the following guidelines:

  • Always take these tablets as prescribed by your doctor. If you’re unsure, consult your doctor or pharmacist.
  • Swallow the tablets whole with water at the same time each day.
  • Continue taking CARDEXIN 0.25 tablets for as long as your doctor recommends. Stopping abruptly can be dangerous without their guidance.

The initial dose of CARDEXIN 0.25 tablets will be determined by your doctor and is typically followed by a maintenance daily dose. For adults and children over 10 years old, the usual dose is as follows:

  • Initial dose is either between 750 micrograms and 1500 micrograms as a single dose or 250 micrograms and 750 micrograms once a day for seven days, depending on your doctor’s instructions. This is then followed by a maintenance dose, typically ranging from 125 micrograms to 250 micrograms daily.

Children under 10 years old have different initial doses, typically between 25 and 45 micrograms per kg of body weight over a 24-hour period. The actual dose depends on the child’s age, and the doctor will decide the best maintenance dose.

For elderly individuals or patients with kidney, thyroid, or bowel disorders, doses may vary based on their specific condition.

If you take more CARDEXIN 0.25 tablets than you should or suspect someone else, especially a child, has swallowed an excessive amount, contact your nearest hospital’s casualty department or your doctor immediately. Take any remaining tablets and the container with you.

If you forget to take a dose, take it as soon as you remember unless it’s almost time for the next one. Never take two doses together. Consult your pharmacist or doctor if you have any concerns.

4. Potential Side Effects of CARDEXIN 0.25 Tablets

Like all medications, CARDEXIN 0.25 tablets can cause side effects, although not everyone experiences them. It’s important to stop taking the tablets and notify your doctor immediately or contact your nearest hospital’s casualty department if you experience:

  • Allergic reactions, such as skin rashes, itching, and swelling of the mouth, tongue, and throat, leading to difficulty swallowing or breathing.
  • Palpitations, chest pain, shortness of breath, or sweating, which could indicate a serious heart problem caused by new irregular heartbeats.

Other possible side effects of CARDEXIN 0.25 tablets include:

  • Common side effects (may affect up to 1 in 10 people): Rash, urticaria, abnormal heartbeat, nausea, vomiting, diarrhea, dizziness, and visual disturbances.
  • Uncommon side effects (may affect up to 1 in 100 people): Depression.
  • Rare side effects (may affect up to 1 in 1,000 people): Changes in blood cells, unusual bruising, nosebleeds, or infections.
  • Very rare side effects (may affect up to 1 in 10,000 people): Decrease in blood platelets, loss of appetite, psychosis, apathy, confusion, headache, stomach pain, enlarged breast tissue in men, fatigue, and general feelings of unwellness.
  • Side effects that cannot be estimated from available data (not known): Disorientation, forgetfulness, delirium, hearing or seeing things that are not there, fits, fatigue, weakness, sleepiness, bad dreams, restlessness, nervousness, agitation, lack of interest in everyday life, blurred vision, intolerance to light, color vision issues, and heart failure.

It’s crucial to report any side effects to your doctor, pharmacist, or nurse, even if they are not listed in the leaflet. Your feedback can help provide more information about the safety of this medicine.

5. How to Store CARDEXIN 0.25 Tablets

To ensure the safety and effectiveness of CARDEXIN 0.25 tablets, follow these storage instructions:

  • Keep the tablets out of sight and reach of children.
  • Store them below 30°C in a dry place and in their original packaging.
  • Do not use CARDEXIN 0.25 tablets after the expiry date indicated on the label, carton, or bottle. The expiry date corresponds to the last day of the specified month.

Remember, do not dispose of medicines through wastewater or household waste. Consult your pharmacist to learn how to properly dispose of medicines you no longer require to protect the environment.

6. Additional Information About CARDEXIN 0.25 Tablets

For your reference, here is some additional information about CARDEXIN 0.25 tablets:


  • The active ingredient is Digoxin BP 0.25 mg.
  • Other ingredients include lactose, Polyvinyl Pyrollidone, Sodium propyl paraben, Isopropyl Alcohol, Methylene Chloride, Croscarmellose Sodium, Magnesium Stearate, and Maize Starch.


  • CARDEXIN 0.25 tablets are available in a blister pack of Printed Alu foil & Clear PVC Film.


  • Bliss GVS Pharma Ltd.
  • Address: 102, Hyde Park, Saki-Vihar Road, Andheri (East), Mumbai – 400072.

Remember, if you have any questions or concerns about CARDEXIN 0.25 tablets, don’t hesitate to reach out to your doctor, pharmacist, or nurse. They are here to ensure your safety and well-being while taking this medication.