Understanding Urosolvine Effervescent Granules

Urosolvine Effervescent Granules are a medical solution designed to help manage conditions like urolithiasis (formation of urinary stones) and gouty arthritis. Let’s break down the key information in a way that’s easy to understand.

What’s Inside?

Each 5g sachet of Urosolvine contains active ingredients like Piperazine Hydrate, Piperazine Citrate, Colchicine Crystals, and Atropine Sulphate. These components work together to address issues related to gout and urinary stones.

How It Works

  • Piperazine: Increases the solubility of urates in the urine, aiding in the treatment of gout and urinary lithiasis.
  • Colchicine: Provides rapid relief from gout pain and possesses anti-inflammatory properties, reducing inflammation during acute attacks.
  • Atropine Sulphate: Included to relieve spasms in the urinary tract.

When to Use

Urosolvine is indicated for acute and chronic gout, gouty arthritis, and prophylaxis against urinary stones.

Dosage Recommendations

  • During Acute Attacks: Dissolve one sachet in half a glass of water, six times daily.
  • To Prevent Acute Attacks: Dissolve two sachets in a glass of water, two times daily.
  • Prophylaxis: Dissolve two sachets in a glass of water, once daily.

What to Avoid

  • Contraindications: Avoid if you are hypersensitive to any components, have blood disorders, acute dehydration, anuria, or hyperkalemia.
  • Side Effects: Possible side effects include nausea, vomiting, abdominal pain, and diarrhea.

Important Notes

  • Pregnancy and Lactation: Contraindicated in pregnant women, and it’s unknown if the drug appears in breast milk.
  • Precautions: Use cautiously in patients with serious gastrointestinal, renal, hepatic, and cardiovascular disorders. Not recommended for children, geriatrics, debilitated patients, and nursing women.

Storage and Instructions

  • Package: Comes in a carton box with 12 sachets, each containing 5g, along with an inner leaflet.
  • Storage: Store at temperatures not exceeding 25°C in a dry place.

Tips for Patients

  • Dosage Adjustment: If vomiting or diarrhea occurs, reduce the dosage.
  • Manufacturer: Manufactured by The Nile Co. for Pharmaceuticals and Chemical Industries in Cairo, Egypt.


Urosolvine Effervescent Granules offer a targeted approach to managing gout and urinary stones. Always follow the prescribed dosage and consult your healthcare provider for personalized advice.