Understanding Novalgin: Your Guide to Pain Relief

Welcome to your comprehensive guide to Novalgin, a medication used for pain relief and fever reduction. Whether you’re a patient or simply seeking information, we’ll break down everything you need to know about Novalgin in simple terms.

What is Novalgin?

Novalgin is a medication that contains metamizole sodium, a compound known for its analgesic (pain-relieving), antipyretic (fever-reducing), and spasmolytic (muscle-relaxing) properties. It’s available in different forms, including tablets and suppositories, making it versatile for various patient needs.

How Does Novalgin Work?

Metamizole sodium, the active ingredient in Novalgin, works by targeting pain and reducing fever. It blocks the production of certain chemicals in the body that are involved in the sensation of pain and the regulation of body temperature, providing relief to individuals dealing with discomfort and fever.

Forms of Novalgin

Novalgin comes in several forms, including:

  • Tablets: These are taken orally, typically swallowed with water.
  • Suppositories: These are inserted into the rectum for individuals who may have difficulty swallowing tablets or require faster relief.

Indications: When to Use Novalgin

Novalgin is recommended for the following conditions:

  • Severe Life-Threatening Fever: When fever reaches dangerous levels.
  • Cancer Pain: To manage pain associated with cancer.
  • Note: Novalgin is not meant for routine pain relief.

Dosage Guidelines

Single Dosing:

  • For oral or rectal administration, the dosage ranges from 8 mg to 16 mg of metamizole per kilogram of body weight.
  • For children with high fever, a typical dose is 10 mg of metamizole per kilogram of body weight.

Multiple Dosing:

  • If a single dose is insufficient or wears off, Novalgin can usually be taken up to four times a day.
  • The lowest effective dose should be used, with a maximum daily limit of 5 grams of metamizole or 70 mg per kilogram of body weight within a 24-hour period.

Special Considerations:

  • Patients with kidney or liver issues should avoid high doses and long-term use.
  • Elderly patients and those with poor overall health should be monitored closely.

Dealing with Side Effects

Common Side Effects:

  • Anaphylactic/Anaphylactoid Reactions: Rare but severe reactions may occur, including skin rash, difficulty breathing, and a drop in blood pressure. Seek immediate medical attention if you experience these symptoms.
  • Isolated Hypotensive Reactions: Occasional drops in blood pressure may occur, especially with intravenous administration. Patients with pre-existing hypotension should be monitored closely.
  • Hematological Reactions: Rarely, blood cell abnormalities such as leucopenia (low white blood cell count) or agranulocytosis (severe reduction in white blood cells) may occur. These require immediate medical attention.

Strategies for Managing Side Effects:

  • If you experience signs of an allergic reaction or hypotension, seek medical help promptly.
  • Regular monitoring of blood counts may be necessary during long-term treatment.
  • Avoid Novalgin if you have a history of allergic reactions to similar medications.

Precautions and Warnings


  • Novalgin should be used with caution in patients with asthma, chronic urticaria, alcohol intolerance, or allergies to certain dyes or preservatives.
  • Close medical supervision is required for patients at risk of severe allergic reactions.


  • Agranulocytosis, a severe blood disorder, may occur rarely. Stop taking Novalgin and seek medical attention if you experience symptoms such as fever, sore throat, or mouth ulcers.
  • Novalgin should be avoided during the first and last trimesters of pregnancy due to potential risks to the fetus.
  • Breastfeeding should be avoided during and for 48 hours after taking Novalgin.


Novalgin is a valuable medication for managing pain and fever in various conditions. Always follow your doctor’s instructions carefully, especially regarding dosage and potential side effects. If you have any concerns or experience unusual symptoms, don’t hesitate to seek medical advice promptly. Your health and well-being are top priorities, and Novalgin is here to support you on your journey to relief.