Understanding Isoptin® 240 mg SR Tablets: Your Comprehensive Guide to Hypertension Management

Isoptin® 240 mg SR Tablets are a medication used for the treatment of hypertension (high blood pressure) and for secondary prevention after acute myocardial infarction (heart attack). In this guide, we’ll explore the uses, benefits, dosage, potential side effects, precautions, and practical tips for using Isoptin® 240 mg SR Tablets to manage hypertension effectively.

What is Isoptin® 240 mg SR Tablet?

Isoptin® 240 mg SR Tablet contains the active drug substance verapamil hydrochloride, which belongs to a class of medications known as calcium antagonists. These tablets work by inhibiting the influx of calcium ions into the heart and vascular smooth muscle cells, thereby reducing peripheral vascular resistance and lowering blood pressure without increasing heart rate.

Indications for Isoptin® 240 mg SR Tablet Use

Isoptin® 240 mg SR Tablet is indicated for:

  • Hypertension: It is used to treat all types of hypertension, either alone or in combination with other antihypertensive medications.
  • Secondary Prevention after Acute Myocardial Infarction: It helps prevent further cardiovascular events after a heart attack.

How Isoptin® Benefits Patients

Isoptin® offers several benefits for individuals with hypertension and those at risk of cardiovascular events:

  • Blood Pressure Control: By reducing peripheral vascular resistance, Isoptin® helps lower blood pressure, reducing the risk of complications associated with hypertension, such as stroke and heart attack.
  • Myocardial Blood Flow: Isoptin® enhances myocardial blood flow by exerting a calcium-antagonistic effect on the vascular smooth muscles of the coronary arteries, improving oxygen supply to the heart muscle.
  • Antiarrhythmic Effect: It has a marked antiarrhythmic effect, particularly in supraventricular arrhythmias, by delaying impulse conduction in the atrioventricular (AV) node and decreasing ventricular rate.

Recommended Dosage and Administration

The dosage and administration of Isoptin® 240 mg SR Tablet are as follows:

  • Regular Use: Take the prescribed dose regularly as directed by your healthcare provider. The tablets should be swallowed whole with some liquid, preferably with or shortly after meals.
  • Initial Dose: The usual starting dose is one tablet in the morning. For patients requiring gradual blood pressure lowering, the initial dose may be half a tablet taken in the morning.
  • Dose Adjustment: Your healthcare provider may adjust the dose based on the severity of your condition. The maximum daily dose should not exceed two tablets, and long-term treatment should not exceed 480 mg per day.
  • Special Populations: In patients with impaired liver function, dosage adjustments may be necessary due to the intensified and prolonged effect of verapamil on the body.

Practical Tips for Using Isoptin® 240 mg SR Tablet

Here are some practical tips for individuals using Isoptin® 240 mg SR Tablet:

  • Take as Directed: Follow your healthcare provider’s instructions carefully regarding dosage and administration. Do not exceed the recommended dose or change the dosing schedule without consulting your doctor.
  • Swallow Whole: Do not crush or chew the tablets. Swallow them whole with a glass of water to ensure proper absorption.
  • Regular Monitoring: Your healthcare provider may recommend regular monitoring of your blood pressure and heart function while taking Isoptin® to assess treatment effectiveness and detect any potential side effects.

Managing Potential Side Effects

While Isoptin® 240 mg SR Tablet is generally well-tolerated, it may cause some side effects in certain individuals. Here’s how to manage common side effects:

  • Cardiovascular Effects: In some cases, high doses of Isoptin® may cause cardiovascular effects such as bradycardiac arrhythmias (slow heart rate), hypotension (low blood pressure), or heart failure. If you experience any unusual symptoms, contact your healthcare provider immediately.
  • Gastrointestinal Symptoms: Constipation is a common side effect of Isoptin®. Ensure an adequate intake of fluids and fiber to help alleviate this symptom. If constipation persists, speak to your doctor for further advice.

Essential Precautions

Before taking Isoptin® 240 mg SR Tablet, consider the following precautions:

  • Contraindications: Avoid Isoptin® in certain cases, including cardiovascular shock, severe conduction disorders, and sick sinus syndrome. Consult your healthcare provider if you have any underlying medical conditions.
  • Drug Interactions: Isoptin® may interact with other medications, including beta-receptor blockers, antiarrhythmics, and inhalation anesthetics, leading to enhanced cardiovascular effects. Inform your doctor about all medications you are currently taking to avoid potential interactions.
  • Special Populations: Use Isoptin® with caution in patients with liver impairment, as the drug’s effect may be intensified and prolonged. Dosage adjustments may be necessary in these cases.


Isoptin® 240 mg SR Tablet is a valuable medication for the treatment of hypertension and secondary prevention after acute myocardial infarction. By understanding its uses, benefits, dosage recommendations, practical tips, and precautions, individuals can optimize their treatment outcomes and reduce the risk of cardiovascular complications. Always consult your healthcare provider for personalized medical advice and guidance regarding the use of Isoptin® 240 mg SR Tablet.