Understanding ACUPAN 20 mg/2 ml: Your Comprehensive Guide

When you receive a prescription for a medication, it’s essential to have a good understanding of what it is, how to take it, and what potential side effects to watch out for. ACUPAN 20 mg/2 ml is one such medication, and in this article, we will provide you with all the necessary information to make an informed decision about its use. Let’s break down the key points step by step.

1. What is ACUPAN Solution for Injection and How is it Used?

  • ACUPAN contains the active ingredient nefopam and belongs to the group called “OTHER ANALGESIC AND ANTIPYRETICS” under the ATC code N02BG06.
  • It is primarily used for the symptomatic treatment of acute painful conditions, especially post-operative pains.

2. What You Need to Know Before Taking ACUPAN

Contra-indications:

  • Do not take ACUPAN solution for injection if:
    • You are allergic to nefopam or any of the other ingredients listed in section 6.
    • You have acute angle glaucoma (an increase in eye pressure).
    • You experience urinary retention linked to uretroprostatic disorders.
    • You have a previous history of convulsions.
    • You are below 15 years of age.

Warnings and Precautions:

  • Be aware that there is a risk of addiction with ACUPAN.
  • If you are using a morphinic drug concurrently, abruptly stopping it can lead to a withdrawal syndrome because ACUPAN is not a morphine agent.
  • Precautions are advised in case of hepatic insufficiency, renal insufficiency, cardiovascular pathology, and for elderly individuals due to its cholinergic effects.

Interactions with Other Medicines:

  • Inform your doctor or pharmacist about any other medicines you are taking or have recently taken, as ACUPAN could interact with them.

Pregnancy and Breastfeeding:

  • The effects of ACUPAN during pregnancy or breastfeeding are unknown, so it is not advisable to use it in these situations.

Driving and Using Machinery:

  • Due to the potential risk of vertigo, individuals using ACUPAN should exercise caution when driving or operating machinery.

3. How to Take ACUPAN Solution for Injection

Dosage:

  • The recommended dose is generally one ampoule, administered intravenously (IV) or intramuscularly (IM), and can be repeated up to six ampoules per day if necessary.

Mode and Way of Use:

  • ACUPAN can be administered by deep intramuscular route (IM) or slow intravenous route (IV), which takes more than 15 minutes. For IV administration, it is advisable to lie down to minimize potential side effects like nausea, dizziness, and sweating.

Frequency and Time to Take It:

  • Injections can be repeated every 6 hours (IM route) or every 4 hours (IV route).

Duration of Treatment:

  • Adherence to the treatment duration prescribed by your physician is essential.

4. Possible Side Effects

  • Like all medications, ACUPAN can cause side effects, but not everyone will experience them.

Common side effects (may affect up to 1 in 10 people):

  • Vertigo
  • Nausea with or without vomiting
  • Somnolence
  • Sweating
  • Pain at the injection site
  • Dry mouth
  • Acceleration of heartbeat
  • Palpitations
  • Urinary retention

Rare side effects (may affect up to 1 in 10,000 people):

  • Excitability
  • Irritability
  • Hallucinations
  • Abuse or drug addiction
  • Convulsions
  • Allergic reactions (urticaria, Quincke’s edema, anaphylactic shock)

Other side effects of unknown frequency:

  • Coma
  • Confusion

If you experience any side effects, consult your doctor or pharmacist. This includes any possible side effects not listed in the leaflet.

5. How to Store ACUPAN Solution for Injection

  • Keep ACUPAN out of the reach of children.
  • After opening/reconstitution/dilution, use the product immediately.
  • Do not use the medicine after the expiry date mentioned on the carton.

6. Contents of the Pack and Additional Information

Ingredients:

  • Active substance: Nefopam hydrochloride 20 mg per 2 mL-ampoule.
  • Other ingredients: Disodium phosphate and sodium phosphate, water for injection.

Pack Description:

  • ACUPAN solution for injection is contained in 2 mL-glass ampoules with a clear, colorless solution. Each box contains 5 ampoules.

Manufacturer Information:

  • Marketing Authorization Holder: BIOCODEX, 7 avenue Gallieni, 94250 Gentilly, France.
  • Manufacturer responsible for batch release: BIOCODEX, 1 avenue Blaise Pascal, BEAUVAIS, France.

This information is based on the leaflet last revised in July 2017. Please consult your doctor or pharmacist for any specific concerns or questions related to your use of ACUPAN. It’s crucial to follow medical advice closely for the safe and effective use of this medication.