Understanding ACNOTIN Capsules for Severe Acne

ACNOTIN capsules contain the active ingredient isotretinoin, an oral retinoid medication used to treat severe acne. Isotretinoin works by reducing oil production, bacteria, and inflammation.

ACNOTIN capsules are approved for:

  • Treating severe types of acne (nodular/conglobate acne or acne at risk of permanent scarring) in adults and adolescents 12+ years old who have gone through puberty
  • Cases where acne has not responded well to antibiotic or other acne treatments
  • Use under close supervision of a dermatologist

How Do ACNOTIN Capsules Work?

  • ACNOTIN capsules contain isotretinoin, which reduces oil/sebum production by the skin’s oil glands
  • This helps deprive acne bacteria of the oily environment they need to multiply
  • Isotretinoin also reduces inflammation associated with acne lesions
  • Over 4-6 months of use, ACNOTIN improves acne and prevents new breakouts in many cases

Taking ACNOTIN Capsules

  • The usual starting dose is 0.5 milligrams per kilogram of body weight per day
    • For a 60 kg person, this equals 30 mg daily
  • Take capsules once or twice daily with food
  • Swallow capsules whole – do NOT chew or crush them
  • After a few weeks, your doctor may adjust the dose between 0.5-1 mg/kg based on response
  • A single 4-6 month ACNOTIN course leads to long-term acne improvement in most patients

Before Taking ACNOTIN

Do NOT take ACNOTIN capsules if:

  • You are pregnant or may become pregnant
  • You are breastfeeding
  • You have liver disease or very high blood fat levels
  • You are taking tetracycline antibiotics

Special Warning for Women

  • ACNOTIN causes severe and irreversible birth defects and miscarriages
  • Strict rules apply for women taking ACNOTIN related to contraception use, pregnancy tests, etc.
  • Do not handle broken/damaged ACNOTIN capsules if pregnant or may become pregnant without wearing gloves

Potential Side Effects

  • Dry skin, lips, eyes, nosebleeds
  • Back pain, joint/muscle aches
  • Headaches, increased sensitivity to light

Rare but Serious Risks

  • Severe allergic reactions
  • Extremely dry eyes, changes in night vision, vision issues
  • Liver inflammation, kidney inflammation
  • Severe stomach pain, severe diarrhea
  • Depression, aggression, mood changes
  • Serious skin rashes
  • Bone/muscle problems

Key ACNOTIN Safety Precautions

  • Use effective contraception if female and sexually active
  • Do NOT donate blood during and for one month after stopping treatment
  • Avoid excessive sun exposure – use sun protection daily
  • Do NOT wax or have cosmetic skin procedures during treatment
  • Have regular visits and blood testing done during treatment
  • Report any new or worsening symptoms to your dermatologist

I hope this clear overview of ACNOTIN capsules helps explain this acne treatment. Discuss any other questions with your dermatologist.

What questions do patients commonly ask about ACNOTIN treatment?

Here are answers to some frequently asked questions:

Does ACNOTIN cure acne forever?

For most patients, one course of ACNOTIN leads to long-term acne clearance, but acne may eventually return for some, especially if very severe initial acne.

How long until I see results from ACNOTIN?

It usually takes 6-8 weeks before improvements become noticeable. Maximum benefits often occur after 4-6 months. Acne may still keep getting better for 1-2 months after stopping.

Can I wax or get facials while taking ACNOTIN?

No. ACNOTIN makes skin more fragile so avoid anything that could cause injury, scarring or skin irritation.

When can I go in the sun on ACNOTIN?

Minimize sun exposure and use SPF 30+ sunscreen if you go out. ACNOTIN makes skin more sun-sensitive. Tanning beds should be avoided completely while on treatment.

Can I drink alcohol with ACNOTIN?

Avoid heavy/binge drinking. But occasional light drinking is OK. Heavy drinking can worsen ACNOTIN side effects like dryness and affect your liver.

Why does my acne seem worse at first?

An initial flare is common as deep cysts rise to the surface early in treatment. Results improve with continued use for most patients.

Let me know if you have any other questions!