Understanding Abiraterone Acetate: A Guide for Patients

In your journey to better health, it’s crucial to have comprehensive information about the medications you are prescribed. This guide will help you understand Abiraterone Acetate Tablet USP 250 mg, which is commonly used in the treatment of prostate cancer. We will cover its purpose, precautions, how to take it, possible side effects, storage instructions, and more.

1. What is Abiraterone Acetate Tablet USP 250 mg, and What is it Used For?

Abiraterone Acetate Tablet USP 250 mg contains a medicine called abiraterone acetate. It is primarily used in the treatment of prostate cancer in adult men that has spread to other parts of the body. This medication works by inhibiting the production of testosterone in the body, which, in turn, can slow down the growth of prostate cancer. In some cases, it is prescribed alongside androgen deprivation therapy.

2. What You Need to Know Before Taking Abiraterone Acetate Tablet USP 250 mg

Before you start taking Abiraterone Acetate Tablet USP 250 mg, there are a few important considerations to keep in mind:

  • Allergies: Do not take this medicine if you are allergic to abiraterone acetate or any of the other ingredients listed in the leaflet.
  • Gender: This medication is exclusively intended for male patients and should not be used by women, especially if pregnant.
  • Liver Health: If you have severe liver damage, it’s essential to discuss this with your doctor.
  • Heart and Blood Pressure: Talk to your healthcare provider if you have been diagnosed with high blood pressure, heart failure, or low blood potassium levels.
  • Cardiovascular Health: If you’ve experienced heart or blood vessel problems, irregular or rapid heart rate, shortness of breath, rapid weight gain, or swelling in the feet, ankles, or legs, inform your doctor.
  • Medication History: Disclose any history of taking a medicine known as ketoconazole in the past for prostate cancer and the need to take this medicine with prednisone or prednisolone.
  • Bone Health: Discuss the potential effects on your bones with your healthcare provider.
  • Blood Sugar: If you have high blood sugar, this is also information your doctor should have.

3. How to Take Abiraterone Acetate Tablet USP 250 mg

Proper administration of this medicine is crucial for its effectiveness:

  • Dosage: The recommended dose is 1,000 mg once a day.
  • Administration: Take the tablet by mouth without food. It’s essential to take it at least two hours after eating and wait for an hour before eating again. Swallow the tablets whole with water, and do not break them.
  • Complementary Medication: Abiraterone Acetate Tablet USP 250 mg is typically taken with a medicine called prednisone or prednisolone, and you should follow your doctor’s instructions regarding these companion medications.
  • Missed Doses: If you forget to take a dose, take it the following day. If you miss multiple doses, consult your doctor promptly.
  • Do Not Stop Abruptly: Do not stop taking Abiraterone Acetate Tablet USP 250 mg or prednisone or prednisolone unless your doctor instructs you to do so.

4. Possible Side Effects

Like any medication, Abiraterone Acetate Tablet USP 250 mg may cause side effects, although not everyone experiences them. Be vigilant and seek medical attention if you notice any of the following:

  • Common Side Effects: These include fluid retention in the legs or feet, low blood potassium, high blood pressure, urinary tract infections, and diarrhea.
  • Less Common Side Effects: Elevated fat levels in your blood, liver function test increases, chest pain, irregular heartbeats (atrial fibrillation), heart failure, rapid heart rate, severe infections (sepsis), bone fractures, indigestion, and blood in urine.
  • Rare Side Effects: These might encompass adrenal gland problems, abnormal heart rhythm (arrhythmia), muscle weakness and/or pain, lung irritation (allergic alveolitis), and, in very rare cases, acute liver failure.
  • Special Attention: If you experience muscle weakness, muscle twitches, or an irregular heart rate (palpitations), these could be signs of low blood potassium.

5. How to Store Abiraterone Acetate Tablet USP 250 mg

Proper storage is essential to maintain the integrity of the medication:

  • Keep the medicine out of the reach of children.
  • Do not use it after the expiry date mentioned on the packaging.
  • There are no specific storage conditions, but do not dispose of it in wastewater or household waste. Consult your pharmacist for proper disposal methods.

6. Contents and Packaging Information

Here’s what you need to know about the components of Abiraterone Acetate Tablet USP 250 mg:

  • Active Ingredient: Abiraterone acetate, 250 mg per tablet.
  • Additional Ingredients: These include lactose monohydrate, microcrystalline cellulose pH-101, cross-carmellose cellulose, sodium lauryl sulfate, PVP K-30, purified water, colloidal silicone dioxide, and magnesium stearate.
  • Appearance: The tablets are uncoated, white to off-white, caplet-shaped, and come with a break line on one side.
  • Packaging: Typically, 60 tablets are packed in a 75CC HDPE bottle with a child-resistant cap, silica gel sachet, and nonabsorbent cotton.

Remember, Abiraterone Acetate Tablet USP 250 mg is a prescribed medication and should be used strictly according to your doctor’s guidance. If you have any questions or concerns, always consult your healthcare provider for clarification and support in your journey to better health. Your well-being is of utmost importance, and understanding your medication is a significant step in achieving it.