Rofenac Suppositories: A Comprehensive Overview

Rofenac suppositories are a medication with a variety of applications, primarily known for their antirheumatic, anti-inflammatory, and analgesic properties. This article aims to provide patients and the general public with a clear understanding of Rofenac, its uses, dosage, precautions, and potential side effects.

Composition and Properties

Rofenac contains Diclofenac Sodium, a nonsteroidal compound known for its antirheumatic, anti-inflammatory, analgesic, and antipyretic properties. It effectively inhibits prostaglandin biosynthesis, addressing inflammation, pain, and fever.

Indications

Rofenac is recommended for various conditions, including:

  • Rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis
  • Non-articular rheumatism
  • Acute musculoskeletal disorders and back pain
  • Painful syndromes of the vertebral column
  • Relief of pain in acute trauma and fractures
  • Control of pain and inflammation in orthopedic, dental, and other surgeries
  • Painful inflammatory conditions in gynecology and primary dysmenorrhea
  • Renal colic and biliary colic (Rotenac ampoules are recommended)
  • Acute attacks of gout

Dosage and Administration

For Adults:

  • The initial daily dose is usually 100-150 mg, with a maximum of 150 mg per day.
  • Dosage may vary based on the severity of the condition.
  • Suppositories can be used at bedtime for additional relief.

For Children:

  • Children from 1 year upwards should be given 0.5-2 mg/kg body weight daily.
  • Caution is advised in children under 12 months, with lower-dose suppositories recommended.

Contraindications and Precautions

Contraindications:

  • Hypersensitivity to Diclofenac
  • Avoid in patients with peptic ulcer or aspirin-induced asthma, acute rhinitis, and urticaria

Precautions:

  • Use with caution in patients with severe hepatic impairment.
  • Exercise caution in cases of impaired cardiac or renal function.
  • Avoid during late pregnancy due to potential risks to the fetus.

Special Warnings

Cardiovascular Risk:

Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of serious cardiovascular events, especially in patients with pre-existing conditions.

Gastrointestinal Risk:

NSAIDs pose an increased risk of serious gastrointestinal adverse events, including bleeding, ulceration, and perforation.

Side Effects and Interactions

While Rofenac is generally well-tolerated, common side effects include gastrointestinal disturbances, headache, and dizziness. It’s essential to monitor for potential interactions with other medications, such as Digoxin, Methotrexate, Cyclosporine, or Lithium.

Storage

Store Rofenac suppositories between 15-30°C.

Conclusion

Rofenac is a versatile medication with multiple applications, providing relief from various inflammatory and painful conditions. However, its use should be approached with caution, adhering to prescribed dosages and considering individual health factors.

Remember, always follow your doctor’s prescription, and consult with healthcare professionals for personalized advice.

Manufactured by SPIMACO