Repatha (evolocumab) 140 or 420 mg solution for subcutaneous injection

Repatha injection (active ingredient name: evolocumab) is used along with diet, alone or in combination with other cholesterol-lowering medications to treat adults with familial hypercholesterolemia (an inherited disorder in which cholesterol cannot be removed from the body properly). Repatha decreases the amount of low-density lipoprotein (LDL) in the blood.

Repatha injection can also be used in adults with cardiovascular disease to reduce the risk of stroke, heart attack,or life-threatening vascular disease. The goal of treatment with Repatha injections in this group of patients is to prevent the build-up of fat on the artery walls (a process known as atherosclerosis), this facilitates blood flow in the arteries, and improves the supply of oxygen to the heart, brain and other parts of the body.

Repatha injections work by blocking the production of harmful cholesterol in the body and thus reducing the amount of cholesterol that may build up on the artery walls. The buildup of cholesterol along the walls of your arteries (a process known as atherosclerosis) reduces blood flow and, in turn, the supply of oxygen to your heart, brain and other parts of your body.

Repatha pre-filled syring
Repatha pre-filled syring

Repatha – Quick Facts

  • Availability: Repatha injections are available in two strengths (concentrations), 140 mg and 420 mg. Not all concentrations may be available in your country of residence.
  • Pharmaceutical form: prefilled syringe.
  • How to use: Injection under the skin ( subcutaneous Injection).
  • The usual dose: The dose is determined according to the patient’s condition and response to treatment. Usually, the starting dose is one injection of a concentration of 140 mg once every two weeks. Your doctor will measure your LDL levels before each injection. Sometimes the dose can be increased to 420 mg once every two weeks or once every four weeks.
  • Storage: Repatha injection should be stored at a temperature between 2°C to 8°C.

Side effects

  • Redness, itching, swelling, pain/sensitivity reactions at the injection site (a local reaction at the injection site).
  • Symptoms of inflammation in the upper respiratory passages such as sore throat, cold, sneezing.
  • Flu-like symptoms (fever, sore throat, runny nose, cough, chills).
  • nausea.
  • Joint pain and muscle pain (a general feeling of aches in the body with a general feeling of being unwell).
  • headache.

Repatha injection price

N.B.: Prices mentioned below, may subject to change later after the date of this article

Repatha injection price in saudi arabia

  • Repatha 140 mg: The package contains 1 pre-filled syringe ready for subcutaneous injection – the package price for 1 syringe is 936 Saudi riyals.
  • Repatha 140 mg: The package contains 2 pre-filled syringes ready for subcutaneous injection – the package price of 2 syringes is 1873 Saudi riyals.
  • Repatha 420 mg: The package contains 1 pre-filled syringe ready for subcutaneous injection – the package price is 1 syringe for 1873 Saudi riyals.

Repatha injection price in Egypt

  • Repatha 140 mg: The package contains 1 pre-filled syringe ready for subcutaneous injection – the package price for 1 syringe is 3,900 Egyptian pounds.
  • Repatha 140 mg: The package contains 2 pre-filled syringes, ready for subcutaneous injection. The price of 2 syringes is 7800 Egyptian pounds.

Repatha injection price in Jordan

  • Repatha 140 mg: The package contains 1 pre-filled syringe ready for subcutaneous injection – the package price is 1 syringe for 188 Jordanian dinars.
  • Repatha 140 mg: The package contains 2 pre-filled syringes, ready for subcutaneous injection. The price of the package is 2 syringes for 376 Jordanian dinars.

Instructions for use

  • The syringe is intended for one use only, and it must be thrown away after use.
  • The medicine is injected under the skin and you can use it yourself or it can be given with the help of another person (a therapist).
  • Keep syringes that are not in use in the refrigerator at a temperature of 2 to 8 degrees Celsius.
  • Do not shake before use.
  • The syringe should not be frozen.
  • The syringe should not be exposed to direct sunlight.
  • Take the syringe out of the cooler (refrigerator), and leave the syringe to heat up at room temperature for 30 to 40 minutes before injecting. Do not heat the syringe, but let it heat up on its own… For more information about injection sites and other useful information, we advise you to read Repatha information leaflet from the link here.

Repatha – Information Leaflet

AR- Patient_Information_Leaflet
Repatha – AR- Patient_Information_Leaflet
ENG-Patient-Information-Leaflet
Repatha – ENG-Patient-Information-Leaflet
Amgen C10AX13  LIPID MODIFYING AGENTS evolocumab 

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