Proximol Compound Effervescent Granules

Proximol Compound Effervescent Granules: For expulsion of ureteric stones – Uric acid dissolvent – Urinary antiseptic.

Dosage

2 teaspoonfuls (or 1 sachet) in 1/2 glass of water three times daily after meals as directed by physician.

Caution: To be used only under medical supervision.

Notice: Patients with urinary lithiasis lithiasis should be advised to intake plenty of fluids to
help extrusion of the calculi.

PROXIMOL COMPOUND is indicated for:

  • As propulsive for ureteric stones.
  • Presence of excess uric acid and urate crystals in urine.
  • Urinary tract infections e.g. pyelitis, cystitis, urethritis.

Composition

Each 100 gm contains: 18.6 mg Halfa bar extract. Equivalent to 8 mg Proximadiol, 6 mg Hexamine, 1 mg Piperazine citrate.

Properties

PROXIMOL COMPOUND acts as an efficient preparation for expulsion of ureteric calculi by the unique action of its content of proximadiol (present in the purified extract of Halfa bar) which produces ureteric dilatation while increasing the propulsive movement of the smooth muscles of the ureter, helping the expulsion of the calculi.

PROXIMOL COMPOUND also dissolves uric acid and urate crystals prevents their deposition in the urinary tract, and these effects are mainly achieved by the action of Piperazine citrate.

In addition to the fore-mentioned properties, PROXIMOL COMPOUND acts as an effective urinary antiseptic due to its content of Hexamine which liberates formaldehyde in the urine. Formaldehyde possesses antibacterial activity against many bacteria responsible for urinary tract infections.

Side Effects

Rarely nausea may occur.

Contraindications

  • Hypersensitivity to any of the components.
  • Impairment of renal or hepatic function.

Use in Pregnancy

During pregnancy its safety has not been justified, so it is better to be avoided during the first trimester as many other new drugs.

Precautions

Some of the rarely used sulphonamides,e.g sulphamethizole and sulpathiazole, may form insoluble precipitate with the liberated formaldehyde in the urine,so, hexamine containing preparations are not recommended to be used concurrently with these sulphonamides.

Other Information

Packing

  • Waxed sealed glass bottles of 60 gm.
  • Sachets of 5 gm. (Boxes of 12 sachets).

Storage

Store below 25 C, protected from humidity.

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