Praluent injection (active ingredient name: alirocumab) is used together with diet, alone or in combination with other cholesterol-lowering medications to treat adults with familial hypercholesterolemia (an inherited disorder in which cholesterol cannot be removed from the body naturally). Praluent lowers the amount of low-density lipoprotein (LDL) in the blood.

Praluent injection can also be used in adults with cardiovascular disease to reduce the risk of stroke, heart attack, or life-threatening vascular disease, such as atherosclerosis), The goal of treatment with Praluent injections in this group of patients is to prevent the build-up of fat on the artery walls (a process known as atherosclerosis), this facilitates blood flow in the arteries, and improves the supply of oxygen to the heart, brain and other parts of the body.

Praluent injection works by blocking the production of harmful cholesterol in the body and thus reducing the amount of cholesterol that may build up on the artery walls. The buildup of cholesterol along the walls of your arteries (a process known as atherosclerosis) reduces blood flow and, in turn, the supply of oxygen to your heart, brain, and other parts of your body.

Praluent- Quick facts

• Availability: Praluent injections are available in two strengths (concentrations), 75 mg and 150 mg. Not all concentrations may be available in your country of residence.
• Pharmaceutical form: Solution for injection in a pre-filled pen (pre-filled syringes in the form of pens).
• How to use: Injection under the skin ( subcutaneous Injection).
• The usual dose: The dose is determined according to the patient’s condition, and the extent of the response to the treatment. In most cases, the starting dose is one injection of 75 mg once every two weeks. Your doctor will measure your LDL levels before each injection. Sometimes the dose can be increased to 150 mg once every two weeks or 300 mg once every four weeks.
• Storage: Praluent injection should be stored at a temperature between 2°C to 8°C.

Side effects

• Redness, itching, swelling, pain/sensitivity reactions at the injection site (a local reaction at the injection site).
• Symptoms of inflammation in the upper respiratory passages such as sore throat, cold, sneezing.
• Flu-like symptoms (fever, sore throat, runny nose, cough, chills).
• nausea.
• Joint pain and muscle pain (a general feeling of aches in the body with a general feeling of being unwell).
• headache.

Praluent injection price

N.B.: Prices mentioned below, may subject to change later after the date of this article

Praluent price in Saudi Arabia

• Praluent 75 mg : The package contains 1 pre-filled pen ready for subcutaneous injection – the package price for 1 pen is 936 Saudi riyals.
• Praluent 75 mg : The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 1873 Saudi riyals.
• Praluent 150 mg: The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 1873 Saudi riyals.
• Praluent 150 mg: The package contains 1 pre-filled pen ready for subcutaneous injection – the package price for 1 pen is 936 Saudi riyals.

Praluent price in Egypt

• Praluent 75 mg: The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 7800 Egyptian pounds.
• Praluent 150 mg: The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 7800 Egyptian pounds.

Praluent price in Jordan

• Praluent 75 mg: The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 218 Jordanian dinars.
• Praluent 150 mg: The package contains 2 pre-filled pens ready for subcutaneous injection – the price of the package is 2 pens for 218 Jordanian dinars.

Instructions for use

• The syringe is intended for one use only, and it must be thrown away after use.
• The medicine is injected under the skin and you can use it yourself or it can be given with the help of another person (a therapist).
• Keep syringes that are not in use in the refrigerator at a temperature of 2 to 8 degrees Celsius.
• Do not shake before use.
• The syringe should not be frozen.
• The syringe should not be exposed to direct sunlight.
• Take the syringe out of the cooler (refrigerator), and leave the syringe to heat up at room temperature for 30 to 40 minutes before injecting. Do not heat the syringe, but let it heat up on its own.

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