Patient Information: Understanding Zinnat (Cefuroxime Axetil) – Your Go-To Guide

Welcome to the patient information leaflet for Zinnat, an antibiotic used to treat a range of infections in both adults and children. This guide aims to provide a clear and straightforward understanding of Zinnat (Cefuroxime Axetil), its uses, potential side effects, and more. Always consult your healthcare provider if you have any questions or concerns.

1. What is Zinnat and What Is It Used For?

Zinnat falls under a class of antibiotics known as cephalosporins, which work by combating bacterial infections. It is prescribed to treat severe infections in various parts of the body, including:

  • Ears, nose, and throat
  • Lungs or chest
  • Urinary tract
  • Skin and soft tissues

Zinnat is also effective against:

  • Sexually transmitted infections (such as gonorrhea)
  • Lyme disease, an infection transmitted through tick bites

To ensure its efficacy, your doctor will identify the bacteria causing your infection and verify its sensitivity to Zinnat during your treatment.

2. Before You Take Zinnat

Do Not Take Zinnat If:

  • You are allergic (hypersensitive) to antibiotics or any of Zinnat’s components. If you suspect this applies to you, consult your doctor before using Zinnat.

Special Care with Zinnat:

  • Not for Children Under 3 Months: Zinnat is not recommended for children under 3 months as it hasn’t been thoroughly studied in this age group.

Taking Other Medications with Zinnat:

Inform your doctor or pharmacist of any medications you are taking or have recently taken, including those without a prescription. Particular attention should be given to medications used to reduce stomach acid (e.g., antacids for heartburn) as they may affect how Zinnat works.

  • Contraceptive Pill: Zinnat may reduce the effectiveness of the contraceptive pill. If you’re on the pill while taking Zinnat, you should also use a barrier method (like condoms) for contraception. Seek advice from your doctor.

Pregnancy and Breastfeeding:

The safety of Zinnat during pregnancy is not fully established. Your doctor will weigh the benefits against the potential risks if you are pregnant. Zinnat’s ingredients can pass into breast milk, so consult your doctor before taking it while breastfeeding.

Driving and Using Machines:

Zinnat may cause dizziness and other side effects that affect alertness. Avoid driving or operating machinery unless you feel well.

Zinnat Suspension Contains Sugar and Aspartame:

Zinnat suspension contains sugar. If you are diabetic, consider this when planning your diet. Zinnat suspension also contains aspartame, a source of phenylalanine. If you have an aspartame intolerance or phenylketonuria (PKU), confirm with your doctor that Zinnat is suitable for you.

3. How to Take Zinnat


  • Always take Zinnat precisely as directed by your doctor. Confirm with your doctor or pharmacist if you have any doubts.
  • If you have kidney issues, your doctor may adjust your dose.
  • Tablets (for Adults): The typical dose is 500 mg to 1 g daily, depending on the severity and type of infection.
  • Tablets (for Children): The starting dose ranges from 250 mg to 500 mg per day, depending on the infection’s severity and type. Take tablets after a meal with water, swallowing them whole without chewing, crushing, or splitting.

Oral Suspension (for Children):

  • The correct dosage depends on factors like the severity of the infection, the child’s weight, and age.
  • Ensure to take it after food. Shake the bottle before use. You can mix the suspension with cold fruit juices or milk drinks but consume it immediately after mixing. For children who can’t take the suspension using a spoon, a dosing syringe with 5 ml markings is supplied for accurate measurement.


If you take more Zinnat than recommended, you may have an increased risk of seizures. Contact your doctor or the nearest hospital emergency department immediately. If possible, take the Zinnat packaging with you.

Missed Dose:

Do not take an extra dose to compensate for a missed one. Resume your regular dosing schedule.

Completing Treatment:

Complete the full course of Zinnat as prescribed, even if you start feeling better. Stopping prematurely may lead to the infection’s return.

4. Possible Side Effects

While Zinnat can effectively treat infections, like all medications, it can have side effects. Not everyone experiences them, and it’s essential to be aware of the following:

Severe Allergic Reactions:

While extremely rare, signs may include:

  • Itchy rash (hives)
  • Swelling of the face or mouth, causing breathing difficulty (angioedema)
  • Collapse

Contact a doctor immediately if you notice any of these symptoms.

Serious Skin Reactions:

Serious skin reactions include:

  • Skin rash that may blister
  • A widespread rash with blisters and skin peeling (toxic epidermal necrolysis)

Contact a doctor immediately if you experience these symptoms.

Fungal Infections:

Zinnat can lead to an overgrowth of yeast (Candida) in the body, resulting in fungal infections like thrush, particularly with prolonged use. Consult your doctor if you suspect a fungal infection.

Severe Diarrhea (Pseudomembranous Colitis):

In rare cases, Zinnat can cause inflammation of the colon, leading to diarrhea with blood, mucus, and stomach pain.

Inform your doctor if you experience any of these symptoms.

Common Side Effects:

Side effects that may affect up to 1 in 10 people include:

  • Fungal infections
  • Headache
  • Dizziness
  • Diarrhea
  • Nausea
  • Stomach pain

Common Side Effects in Blood Tests:

Side effects that may appear in blood tests include:

  • Increased white blood cell count (eosinophilia)
  • Increased liver enzymes

Uncommon Side Effects:

Uncommon side effects, affecting up to 1 in 100 people, may include:

  • Vomiting
  • Skin rashes

Uncommon Side Effects in Blood Tests:

Uncommon side effects in blood tests may involve:

  • Decrease in blood platelets (thrombocytopenia)
  • Decrease in white blood cells (leukopenia)

Rare Side Effects:

Rare side effects, affecting up to 1 in 1,000 people, include:

  • Severe diarrhea (pseudomembranous colitis)

Very Rare Side Effects:

Very rare side effects, affecting up to 1 in 10,000 people, may consist of:

  • Allergic reactions
  • Severe skin reactions
  • High fever
  • Yellowing of the whites of the eyes or skin (jaundice)
  • Liver inflammation (hepatitis)

Very rare side effects that may appear in blood tests:

  • Rapid destruction of red blood cells (haemolytic anaemia)

5. How to Store Zinnat

  • Keep Zinnat tablets out of children’s reach. Store them at temperatures not exceeding 30°C.
  • Zinnat suspension, once mixed with the right amount of water, should be kept in the fridge between 2°C and 8°C.
  • Discard the bottle ten days after opening it. Do not dispose of the medicine in wastewater or household trash. Consult your pharmacist for proper disposal methods to protect the environment.

6. Further Information

What Zinnat Contains:


  • The active ingredient is cefuroxime axetil, available in different strengths: 125 mg, 250 mg, or 500 mg.
  • Inactive ingredients include microcrystalline cellulose, croscarmellose sodium, and others.

Oral Suspension:

  • Each 5 ml of solution contains 125 mg/250 mg of cefuroxime axetil when mixed with the correct amount of water.
  • Inactive ingredients include aspartame, xanthan gum, and more.


  • Zinnat tablets come in various strengths and are white to cream in color.
  • Zinnat suspension is a dry, white to off-white granule with a tutti-frutti flavor.

Manufacturer: Zinnat is manufactured by Glaxo Operations UK Limited, United Kingdom.

Remember, Zinnat is a valuable tool in the fight against infections, but it should only be used under the guidance of a healthcare professional. If you have questions or concerns, don’t hesitate to reach out to your doctor for clarification and guidance. Your well-being is our priority.