Overview of XATRAL LP 10mg Prolonged-Release Tablets

XATRAL LP 10mg tablets contain the active drug alfuzosin and are used to treat symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH). This post covers key details about this medication including its uses, how it works, proper dosage, side effects, contraindications, drug interactions, and storage recommendations.

What is XATRAL LP 10mg Used For?

XATRAL LP 10mg prolonged-release tablets are specifically indicated for:

  • Relieving difficulty urinating caused by prostate enlargement
  • Relieving urinary retention along with a urinary catheter if unable to urinate

It works by relaxing muscles in the prostate and bladder neck to improve urine flow and relieve associated symptoms.

XATRAL LP 10mg tablets are intended for use in adult men only. They should not be taken by women or children under age 18.

How XATRAL LP 10mg Works

The active drug in XATRAL tablets is alfuzosin hydrochloride, which belongs to a class of medications called alpha-blockers.

Alfuzosin blocks alpha-1 receptors in the prostate and bladder smooth muscle. This action relaxes tightened muscles to improve urine flow rate and urinary symptoms.

Effects begin within a few hours but maximal improvements may take 2-3 weeks. Most patients require ongoing long term treatment for continued relief.

Proper Dosage and Administration

The standard dosage of XATRAL LP 10mg tablets is:

  • One tablet daily
  • Take immediately after your evening meal
  • Swallow whole with water – Do NOT chew, crush or split tablets

Follow your physician’s instructions for optimal duration of treatment. Do not increase or decrease dosage unless directed by your doctor.

XATRAL LP uses specially formulated prolonged-release tablets that slowly deliver the medication over 24 hours. Taking doses properly with food is important to get the full effects.

Missed Doses and Overdose

If you miss taking a scheduled dose, simply take your next regularly scheduled tablet. Do NOT take two tablets together to try to “catch up”.

Taking excessively high doses of XATRAL LP 10mg may increase risks of low blood pressure, dizziness or other reactions. Overdoses require emergency medical care. Take the medication packaging with you to help doctors determine risks and treatment options if an overdose is suspected.

Side Effects and Contraindications

Potential side effects when taking XATRAL LP 10mg may include:

  • Dizziness
  • Headache
  • Stomach upset
  • Fatigue
  • Nasal congestion

More serious side effects are possible but rare, such as liver inflammation, serious allergic reaction, or persistent painful erection requiring medical treatment.

Contraindications where the risks of using XATRAL LP 10mg are too high include:

  • Allergy to alfuzosin or other ingredients
  • History of low blood pressure
  • Severe liver or kidney disease
  • Taking certain HIV, hepatitis C, antifungal or antibiotic medications (may interact)

Discontinue XATRAL LP 10mg and seek prompt medical attention if any signs of angioedema, liver damage, or heart problems occur.

Does XATRAL LP 10mg Interact with Other Drugs?

XATRAL LP 10 mg tablets should NOT be used with certain HIV, hepatitis C, antifungal or antibiotic medications because serious interactions may occur. Taking nitrates for heart disease also raises interaction risks.

Inform your doctor about ALL medications being taken to identify possible medication interactions before starting or stopping this treatment.

Using XATRAL LP 10mg with blood pressure drugs like doxazosin also requires caution due to additive effects that can trigger excessive blood pressure drops. Adjustments to medication regimens are sometimes needed to maintain safety and efficacy if interactions are expected.

How to Properly Store XATRAL LP 10mg

XATRAL LP 10mg tablets should be stored properly to maintain full potency:

  • Store at controlled room temperature below 30°C
  • Keep container tightly sealed when not in use
  • Protect from excessive heat, freezing and humidity
  • Avoid storing in direct sunlight
  • Keep all medications safely out of sight and reach of children and pets

Check expiration dates on the packaging and do not use outdated products. Properly stored XATRAL LP 10mg tablets remain stable until the imprinted expiration date. Any unused product should be discarded once this date has passed.

Manufacturer Information

XATRAL LP 10mg prolonged-release alfuzosin tablets are manufactured by:

Sanofi Winthrop Industrie
30-36 Avenue Gustave Eiffel
37100 Tours, France


In summary, XATRAL LP 10mg provides once daily alfuzosin treatment for urinary problems in men caused by enlarged prostates. Follow all dosing guidelines, contraindication warnings and potential interaction precautions when using this medication.

Report any worrisome side effects or drug reactions to your prescribing physician right away. Do not increase, decrease or stop treatment doses of XATRAL LP 10mg without first consulting your doctor.