Overview of Vastarel MR

Vastarel MR is a medication used in the treatment of angina pectoris, commonly known as chest pain. In this post, we will discuss what angina is, how Vastarel MR works, its benefits and risks. The information provided is based on the patient information leaflet from the manufacturer to help explain this medication in simple terms.

What is Angina?

Angina is a condition where a person experiences chest pain or discomfort due to coronary heart disease. The heart muscle does not get enough oxygen-rich blood which causes chest pain or discomfort. Angina is not a heart attack, and it does not permanently damage the heart muscle.

There are two main types of angina:

  • Stable angina: This type of angina occurs predictably, such as during physical exertion or emotional stress. It is usually relieved by rest or medication.
  • Unstable angina: This type of angina occurs more frequently or severely than before, or in a new way, such as during less physical activity or at rest. It may be a sign of a heart attack developing.

Some common triggers for angina pain include:

  • Physical exertion or stress (like walking up stairs, carrying groceries, etc.)
  • Emotional stress
  • Cold weather
  • Heavy meals

The chest pain or discomfort of angina is usually located in the central chest area and may feel like uncomfortable pressure, tightness, pain, burning or fullness. It can sometimes spread to the shoulders, arms, neck, jaw or back.

How Does Vastarel MR Work?

Vastarel MR (trimetazidine dihydrochloride) is a medication that works by improving blood flow and oxygen supply to the heart during physical activity or stress when more oxygen is needed.

It works by partially blocking an enzyme called long-chain 3-ketoacyl coenzyme A thiolase which plays a role in fatty acid metabolism. This shift toward preferential use of glucose as an energy source for the heart helps maintain adequate oxygen supply when oxygen demand increases.

Vastarel MR is used in combination with other heart medicines to help treat stable angina pectoris. It is not intended for use alone and does not cure or prevent angina attacks on its own.

Benefits of Vastarel MR

Some potential benefits of Vastarel MR based on clinical studies include:

  • Reduction in frequency of angina attacks
  • Lengthening of time before chest pain occurs during exercise or stress testing
  • Improved quality of life by allowing patients to remain physically active with less limitations from angina pain

Risks and Precautions

As with any medication, Vastarel MR may cause side effects, though many patients tolerate it well. Some important risks and precautions to be aware of include:

  • Not recommended for patients with Parkinson’s disease, severe kidney problems, or allergy to any ingredients
  • May cause dizziness, headache, stomach upset, rash or weakness – see a doctor if severe or ongoing
  • Eldery patients may experience movement problems like tremors – see doctor for medical review
  • Does not treat acute angina attacks – seek medical help during episodes
  • Use caution if driving or using heavy machinery due to risk of dizziness
  • Not recommended during pregnancy or breastfeeding – discuss with your doctor
  • Tell your doctor about other medications you take to avoid interactions
  • Seek emergency medical help for signs of allergic reaction like swelling of the face/throat

In summary, Vastarel MR provides an additional option to help manage stable angina when used properly under medical guidance. Always follow dosing instructions carefully and report any side effects or concerns to your prescribing doctor right away. Proper angina treatment can help improve quality of life.