Neo-Minophylline Syrup Bronchodilator & Expectorant

Indications: Neo-Minophylline syrup is indicated for the sympathomimetic treatment of bronchospasms associated with such conditions as bronchial asthma, chronic bronchitis and pulmonary emphysema. Guaiphenesin helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.


As directed by the physician or as follows:

Children 6-9 years: one and half teaspoonful 3-4 times daily after meals.

Children up to 16 years: one and half to two teaspoonful 3-4 times daily after meals.

Over 16 years: 2-3 teaspoonful 3-4 times daily after meals.


Each 100 ml contains Active ingredients: 1 mg Theophylline anhydrous, 0.60 mg Guaiphenesin

Theophylline is a bronchodilator by relaxing bronchial smooth muscle, oppose the effects of many broncho-constrictor mediators, and also relaxes smooth muscle in the urinary & biliary ways. Central stimulant Analeptic respiratory.

Guaiphenesin helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.


Hypersensitivity to Theophylline, concomitant use with ephedrine in children.

Side Effects

Variable from one subject to the other, essentially: nausea, vomiting, epigastric pain, Cephalalgia, excitation, insomnia, tachycardia…The side effects may be the first sign of over dosage The appearance of the convulsion is the sign of confirmed poisoning, but can be the first sign of it, notably at the child.


  • To be used with big prudence at the young child.
  • An overdose can result from inappropriate doses, of repeated administration in a too short intervals, or by potentialization with associated medicines.
  • Because of the big interpersonal variations of the metabolism of the Theophylline, it is necessary to adapt the doses according to the undesirable reactions and/or of the blood rates.

Warnings & Precautions

  • Don’t use for children under 6 years.
  • The patients response to therapy should be carefully monitored.
  • Worsening of asthma symptoms requires urgent medical attention.
  • Use with caution in patients with cardiac arrhythmias, peptic ulcer, hyperthyroidism, severe hypertension, acute porphyria, hepatic dysfunction, chronic alcoholism, acute febrile illness and chronic lung disease.
  • Smoking and alcohol consumption may increase theophylline clearance and increased doses of theophylline are therefore required. In patients with cardiac failure, hepatic dysfunction/dis ease and fever the reverse is true and these patients may require a reduced dosage.
  • Alternative bronchodilator therapy should be used in patients with a history of seizures.
  • It is not recommended that the product be used concurrently with other preparations containing xanthine derivatives.
  • Warnings: Xanthines can potentiate hypokalaemia resulting from beta-2-agonist therapy steroids, diuretics and hypoxia. Particular caution is advised in severe asthma. It is recommended that serum potassium levels are monitored in such situations.
  • Guaiphenesin not suitable for children under 12 years of age.

Pregnancy & Lactation

In case of administration of the drug in the end of pregnancy. possibility of tachycardia, and of hyperexcitability in the neonates. It shouldn’t be taken during pregnancy & lactation.

Further Information


Each 100 ml contains Active ingredients: 1 mg Theophylline anhydrous, 0.60 mg Guaiphenesin

Inactive ingredients: Methyl paraben sodium, propyl paraben sodium, sucrose,aspartam, peppermint oil, orange oil, sodium hydroxide, propyleneglycol, quinoline yellow, methylene blue, distilled water.

Drug Interactions

Cimetidine, allopurinol, corticosteroids, frusemide, isoprenaline, oral contraceptives, thiobendazole, ciprofloxacin, erythromycin or other macrolide antibiotics and the calcium channel block ers, diltiazem and verapamil, nizatidine, norfloxacin, isoniazide, fluconazole, carbimazole, mexiletine, propafenone, oxpentifyl line, disulfiram, viloxazine, interferon alfa, and influenza vaccine increase plasma theophylline concentrations. A reduction of the theophylline dosage is recommended.

Phenytoin, carbamazepine, barbiturates, rifampicin, sulphinpyrazone, ritonavir, primidone and aminoglutethimide may reduce plasma theophylline concentrations and therefore the theophylline dosage may need to be increased.

Theophylline can increase lithium excretion.

The concomitant use of theophylline and fluvoxamine should usually be avoided. Where this is not possible, patients should have their theophylline dose halved and plasma theophylline should be monitored closely.

Plasma concentrations of theophylline can be reduced by concomitant use of the herbal remedy St John’s wort.

Other interactions:

  • B-Blockers: antagonism of bronchodilation.
  • Ketamine: reduced convulsive threshold.
  • Doxapram: increased CNS stimulation Also see Warnings.
  • Don’t use the association of troleandomycine which can provoke a risk of overdosage.
  • It is agreed to be used prudently with Erythromycin that can increase the blood concentration of the Theophylline.
  • This risk remained to value in the case of the other macrolides.


Carton box contains bottle of 120 ml. Bottles of 100, 125 ml for export and tenders and inner pamphlet.

This Is A Medicament

Medicament is a product which affects your health, and its consumption contrary to instructions is dangerous for you. Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sold the medicament.

The doctor and the pharmacist are experts in medicine, its benefits and risks. Do not by yourself interrupt the period of treatment prescribed for you. Do not repeat the same prescription without consulting your doctor. Keep all medicines out of the reach of children.

Neo-Minophylline Syrup- Arabic Information: نيومينوفيللين شراب موسع للقصبات وطارد للبلغم