Navigating Digestive Wellness with Domperidone SEDICO: A Comprehensive Guide

Embarking on a journey to understand and manage digestive concerns can be overwhelming. Domperidone SEDICO Tablets, Oral Suspension, and Suppositories offer a multifaceted solution designed to address issues ranging from nausea and vomiting to gastrointestinal disorders. In this guide, we will explore the composition, indications, positive impacts, suggested doses, potential side effects, and practical tips for those considering or currently using Domperidone SEDICO.

Decoding the Components

Understanding the components of Domperidone SEDICO is crucial to comprehending how this medication aids in digestive wellness:

  1. Domperidone (Tablets, Oral Suspension, Suppositories): Domperidone, a derivative of benzimidazole, acts as both a prokinetic and antiemetic. It operates as a dopaminergic antagonist, increasing lower esophageal sphincter pressure, inhibiting gastric fundus relaxation, enhancing antral contractility, and relaxing the pyloric sphincter.

Component Benefits

Let’s delve into how each component benefits the patient:

  • Domperidone: The prokinetic properties of Domperidone aid in normalizing digestive processes. It helps by increasing lower esophageal sphincter pressure, promoting gastric emptying, and preventing reflux. As an antiemetic, it alleviates nausea and vomiting, enhancing overall digestive comfort.

Indications and Positive Impact

Domperidone SEDICO demonstrates its versatility through a range of indications, each contributing to digestive well-being:

  1. Nausea & Vomiting Treatment: Domperidone is indicated for the short-term treatment of nausea and vomiting of various origins, including functional, infectious, organic, or those induced by radiotherapy or drug therapy.
  2. Gastrointestinal Disorders: It is effective in addressing gastrointestinal disorders associated with delayed gastric emptying, gastro-esophageal reflux, and esophagitis.

Suggested Doses

Understanding the appropriate dosage is crucial for optimal results. Here are the suggested doses for different formulations:

  • Tablets:
    • Nausea & Vomiting: 2 tablets 3-4 times daily.
    • Gastrointestinal Disorders: 1 tablet 3 times daily (preferably 15-30 minutes before meals). If necessary, one tablet can be taken before bedtime, and the dosage can be doubled when required.
  • Oral Suspension:
    • Adults: 10-20 ml, 3-4 times daily before meals and bedtime (according to severity).
    • Children: 2.5 – 5 ml per 10 kg body weight, 3-4 times daily before meals and bedtime (according to severity).
  • Suppositories:
    • Adults: 30-60 mg every 4-8 hours.
    • Children: Dosage varies based on age, ranging from 10 mg for those under 2 years to 30 mg or 60 mg for older children.

Advice and Instructions

To optimize the benefits of Domperidone SEDICO, consider the following advice and instructions:

  1. Renal Insufficiency: Reduce the dose frequency in patients with renal insufficiency to ensure safe and effective use.
  2. Parkinsonian Patients: In the treatment of nausea and vomiting in Parkinsonian patients, therapy may be continued for a maximum of 12 weeks.
  3. Concomitant Use with Antacids: When antacids or antisecretory agents are used concomitantly, take them after meals, avoiding simultaneous intake with Domperidone.

Managing Side Effects

While Domperidone is generally well-tolerated, it’s crucial to be aware of potential side effects and adopt strategies to manage them:

  1. Increased Prolactin Concentrations: Monitor for signs of increased prolactin concentrations, which may lead to galactorrhoea or gynaecomastia.
  2. Reduced Libido: Be aware of reduced libido as a potential side effect and consult your healthcare provider if this occurs.
  3. Central Effects: Watch for central effects such as extrapyramidal dystonic reactions or drowsiness. If experienced, seek medical attention.

Practical Tips and Advice

For a seamless experience with Domperidone SEDICO, consider these practical tips:

  1. Storage: Keep Domperidone SEDICO at a temperature not exceeding 30°C, and store suppositories at a temperature not exceeding 15°C. Always keep medications out of reach of children.
  2. Duration of Use: Adhere to the recommended duration of use, especially in Parkinsonian patients, to prevent potential complications.


In conclusion, Domperidone SEDICO emerges as a valuable ally in the realm of digestive wellness. With its well-balanced composition and diverse formulations, it addresses various digestive concerns, providing relief from symptoms such as nausea, vomiting, and gastrointestinal disorders. By understanding its components, indications, suggested doses, and potential side effects, individuals can confidently incorporate Domperidone SEDICO into their wellness journey. Always consult with a healthcare professional for personalized advice and guidance tailored to your specific health needs.