Mupirax is indicated for:

  • Treatment of primary & secondary superficial skin infections.
  • Treatment of various topical bacterial infections, such as impetigo, folliculitis & furunculosis caused by S. aureus (including Methicillin resistant Staphylococcus aureus (MRSA), beta hemolytic streptococcus, S. pyogenes.
  • Treatment of burn wound infections caused by MRSA infections.
  • Treatment of infected wounds & lacerations.

Dosage & Administration

Adults & children: Mupirax ointment should be applied to the affected area up to three times daily for up to 10 days.

The area may be covered with a gauze dressing if desired.


Each gram of Mupirax ointment contains 20 mg mupirocin.


Mupirax, mupirocin, is a topical antibacterial agent which inhibits bacterial protein synthesis & RNA synthesis by binding to isoleucyl transfer-RNA synthetase.

It is mainly active against aerobic isolates of busiaal) Staphylococcus aureus (including Methicillin-resistant & B-lactamase producing strains), S. epidermidis, S. saprophyticus & Streptococcus pyogenes are susceptible to mupirocin.

It is also active against gram-negative organisms, such as Escherichia coli & Haemophilus influenzae. Mupirax shows no cross-resistance with other antibiotics.

Side Effects

Mupirocin is usually well tolerated but local reactions such as burning, stinging, & itching may occur after its application to the skin.


Hypersensitivity reactions to Mupirax or other ointments containing polyethylene glycols. Mupirax ointment formulation is not suitable for ophthalmic or intranasal use.


When Mupirax ointment is used on the face, avoid contact with the eyes.

Open wounds: Polyethylene glycol can be absorbed from open wounds & damaged skin & is excreted by the kidney. As with other polyethylene based ointments, it should be used with caution if absorption of large quantities of polyethylene glycol is possible, & especially if there is evidence of moderate or severe renal impairment.

Pregnancy: It should be used during pregnancy only if clearly needed, as there are no adequate and well controlled studies in pregnant women.

Lactation: It is not known whether mupirocin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised to a nursing woman.

Drug-Drug Interactions

The effect of the concurrent application of topical mupirocin ointment and other topical products has not been studied.

Other Information

Patient’s instructions

  • Use this medication only as directed by your doctor.
  • It is for external use only.
  • Avoid contact with the eyes.
  • The medication should be stopped & your doctor contacted if irritation, severe itching, or rash occurs.


Mupirax ointment is supplied in tubes of 10 g and 30 g each. Store at room temperature. Keep out of reach of children

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ميوبيراكس مرهم مضاد حيوى
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دواعى الإستعمال مضاد للبكتيريا واسع المجال
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