LIOMETACEN: Your Comprehensive Guide to Pain Relief

Liometacen is a potent analgesic medication known for its efficacy in managing acute painful episodes associated with inflammatory musculoskeletal disorders. This guide aims to provide detailed insights into Liometacen, covering its composition, indications, dosage recommendations, precautions, contraindications, side effects, and packaging information.


Liometacen contains the following active ingredient:

  • Meglumin Indomethacinate: A water-soluble salt of indomethacin, known for its analgesic properties.


Liometacen is indicated for the symptomatic treatment of acute painful episodes during inflammatory musculoskeletal disorders. It provides rapid relief from pain associated with conditions such as arthritis, sprains, strains, and other inflammatory conditions affecting the muscles and joints.

Dosage Recommendations

The recommended dosage of Liometacen is 1-2 ampoules per day, administered via the intramuscular route. It is essential to follow the prescribed dosage regimen as directed by a healthcare professional to achieve optimal therapeutic effects. In cases where intravenous administration is necessary, it should be done exclusively in a hospital setting, following dilution and infusion protocols.


Liometacen is contraindicated in the following cases:

  • Children under 14 years of age
  • Pregnancy and breastfeeding
  • Individuals with peptic ulcers or active gastrointestinal ulcerative lesions
  • History of recurrent gastrointestinal ulcerative lesions
  • Known hypersensitivity to salicylates or indomethacin
  • Epilepsy or Parkinson’s disease
  • Intensive diuretic treatment
  • Ongoing hemorrhages or hemorrhagic diathesis
  • Treatment with anticoagulant drugs


Before using Liometacen, certain precautions should be considered:

  • Patients with renal or hepatic impairment, cardiac insufficiency, or other pre-existing medical conditions require careful monitoring during treatment.
  • Administration shortly before delivery may delay birth and cause hemodynamic alterations in the neonate’s pulmonary circulation.
  • Asthmatic or sensitive individuals may experience bronchospasm attacks or allergic reactions.
  • Regular monitoring for gastrointestinal, ocular, and nervous adverse reactions is essential to detect and manage side effects promptly.

Side Effects

While Liometacen is generally well-tolerated, some individuals may experience side effects such as:

  • Gastrointestinal disturbances including nausea, vomiting, and diarrhea
  • Eye-related issues such as sight disturbances and retinal disturbances
  • Hepatitis with jaundice (rare)
  • Blood disorders including anemia, agranulocytosis, and thrombocytopenic purpura
  • Nervous system symptoms such as mental depression, confusion, headache, vertigo, and hearing disorders
  • Allergic reactions including rashes, urticaria, and asthma
  • Other adverse effects such as edema, hypertension, and vaginal hemorrhages

Administration and Cautions

Liometacen injections should be administered slowly into the upper external quadrant of the buttocks muscle, following strict sterilization protocols. Regular monitoring of liver function and blood parameters is recommended during prolonged treatment. Patients should adhere strictly to the prescribed dosage to avoid adverse reactions. Caution is advised while driving or operating machinery due to potential dizziness or confusion caused by the medication.

Packaging Information

Liometacen is available in a box containing 6 lyophilized ampoules and 6 solvent ampoules. It should be stored out of the reach of children in a cool, dry place.


In conclusion, Liometacen offers effective pain relief for individuals suffering from inflammatory musculoskeletal disorders. However, it is essential to use this medication under the guidance of a healthcare professional and adhere to prescribed dosage regimens to minimize the risk of adverse effects. If you have any concerns or experience any side effects while using Liometacen, consult your healthcare provider for further guidance.