Composition: Each 100 g contains:

• 7.810 gm Disodium hydrogen phosphate.
• 15.620 gm Sodium sulphate.
• 15.620 gm Magnesium sulphate.
• 0.120 gm Saccharin sodium.
• Effervescent base to 100.000 gm.

Properties

Laxel is a mixture of salts prepared in a nicely flavoured, easily soluble, effervescent granular form. The main ingredients include magnesium sulphate, the salt with a specific cholagogue action in the drainage of the biliary passages. This action is achieved by direct relaxation of the sphincter of the common bile duct, simultaneously with contraction of the gall bladder, this action allows a direct flow of the bile into the duodenum, thus preventing stasis and so safeguard against infection and stone formation.

Laxel also contains sodium sulphate and sodium phosphate, both are poorly absorbed salts which retain water in the intestinal tract and produce a mild laxative effect. With the ensured flow of bile, this regulates the activity of the bowels and ensures better digestion and more complete evacuation.

Indications & Usage

• Chronic cholecystitis.
• Constipation, ( occasional or habitual ).

Contra-Indications

• Addison’s disease.
• Osteomalacia.
• Infected urolithiasis.
• Long term treatment of patients with severe renal impairment.
• Congestive heart failure, acute dehydration and oedema.
• In patients with gastrointestinal obstruction, inflammatory bowel disease, Acute pancreatitis, hypoparathyroidism and severe adrenal insufficiency.

Side Effects

• Nausea, vomiting, or diarrhea may occur.
• Hypermagnesaemia is uncommon after oral administration except in renal impairment.

Drug Interactions

• Magnesium salts may decrease the absorption and the therapeutic effect of aminoquinolines ( e.g. chloroquine),  nitrofurantoin, tetracyclines and biphosphonate.
• Antacids containing Aluminum or Calcium, and Iron containing medications may bind to phosphate and prevent its absorption.
• Acidification of urine due to phosphates may increase elimination and decrease the therapeutic effect of anorexants and sympathomimetic drugs, and may increase bioavilability of chlorpropamide and enhance the hypoglycemic action.

Warnings & Precautions

• Give with caution to patients with hyperphosphatemia and hypertension.
• Chronic diarrhea due to long term administration may result in electrolyte imbalance .
• Caution should be taken in patients receiving diuretics, in elderly, debilitated patients and those in pre-existing electrolyte disturbance.
• During  pregnancy, lactation and in paediatrics less than 4 years use only as directed by physician.

Dosage & Administration

One packet in half a glass of water in the morning. This dose may be repeated twice or more daily before meals.

Packing

12 packets each of 5 gm.

Storage

Store below 30°C and R.H. below 70 %.

• Medicament is a product which affects your health. and its consumption contrary to instructions is dangerous for you.
• Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sales the medicament.
• The doctor and the pharmacist are experts in medicine. it’s benefits and risks.
• Do not by yourself interrupt the period of treatment prescribed for you.
• Do not repeat the same prescription without consulting your doctor.
• Keep medicament out of children reach.

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