Isoptin SR 240mg Capsules

Composition

Each SR tablet contains: Verapamil Hcl. 240 mg.

Properties

  • Isoptin is a calcium antagonist for the treatment of coronary insufficiency hypertension & cardiac arrhythmia.
  • Verapamil inhibit slow calcium current flowing into the cell of the heart & smooth muscle cells and thus reduces the amplitude of muscle contraction. The myocardial O2 demand is lowered. It relieves coronary spasm after enhancing myocardial blood flow.
  • Its antihypertensive action is due to decrease in peripheral vascular resistance.
  • It has an antiarrythmic effect specially in supra ventricular arrhythmia by delaying impulse conduction in the AV node.

Indications

  • It is used in chronic coronary insufficiency & long term treatment of angina pectoris.
  • It is effective also in cardiac infarction, extrasystoles, atrial tachyarrythmia, atrial flutter & atrial fibrillation.

Dosage & Administration

Unless other wise prescribed, one tablet to be swallowed once daily. A dose of 480mg should not be exceeded.

Contra-Indications

  • It should not be given in cardiovascular bradycardia, congestive heart failure, and complicated acute myocardial infarction.
  • Pregnant & breast feeding women are not recommended to use the drug unless it is essential for their well being.

Drug – drug Interactions

Isoptin enhances as the action of other drugs as ß blockers, anesthetics, cardiovascular cyclosporin & theophyllin. While it decreases the action of lithium, rifampicin, phenytoin & phenobarbital.

Side Effects

In oral administration, it is well tolerated, unless in some cases, constipation can be seen.

Packing

Box of 10 sustained release tablet in strip.

ATC Code: C09BB10 / AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM


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