Imuran Medicine

Imuran is a medication containing azathioprine as the active ingredient. It is an immunosuppressant drug that affects the body’s immune response. Therefore, it is used to treat certain autoimmune diseases, as well as prevent organ transplant rejection.

Imuran and COVID-19

Imuran suppresses the immune system, which may increase the risk of contracting COVID-19. However, patients should not stop taking Imuran on their own, but rather adhere to safety precautions to prevent infection.

Imuran for Ulcerative Colitis

The Imuran drug is used to treat moderate to severe symptoms of ulcerative colitis after other medications like corticosteroids have failed. It may also be used with other medications to treat ulcerative colitis.

Imuran Side Effects

Click here to learn more about the side effects of using azathioprine, the generic name for Imuran.

What is Imuran Used For?

As an immunosuppressant, azathioprine is used for:

  • Preventing organ transplant rejection, such as kidney transplants
  • Treating rheumatoid arthritis
  • Treating ulcerative colitis
  • Treating Crohn’s disease
  • Treating lupus nephritis

Imuran Contraindications

Azathioprine use is prohibited in the following cases:

  • Hypersensitivity to azathioprine
  • Rheumatoid arthritis patients previously treated with alkylating agents
  • Pregnancy – it may harm the fetus

Azathioprine should also be avoided during breastfeeding because small amounts may be excreted in breast milk and harm the infant.

Imuran Precautions

Inform your doctor about the following before starting azathioprine treatment:

  • If you are pregnant, planning to become pregnant, or breastfeeding
  • If you are taking any treatments, supplements, or herbal preparations
  • If you have any drug or food allergies
  • If you have liver or kidney disease
  • If you have digestive conditions like Crohn’s or ulcerative colitis
  • If you have an infection, frequent infections, or recently had a vaccination
  • If you have a history of cancer, bone marrow disorders, anemia, low white blood cells, bleeding, or unexplained bruising
  • If you have an enzyme deficiency or recently received a blood transfusion
  • If you are taking methotrexate or adalimumab
  • If you develop signs of infection, contact your doctor immediately
  • Long-term use may increase cancer risk in some patients

Imuran Drug Interactions

Inform your doctor about all medicines, supplements, vitamins, and herbs you are taking before starting azathioprine. It may interact with:

  • Gout medications
  • Aminosalicylates for inflammatory bowel disease
  • Biologics and immunosuppressants
  • Medications affecting the immune system
  • Blood pressure medications
  • Blood thinners like warfarin
  • Hepatitis C medications
  • Live virus vaccines – avoid during azathioprine treatment

Imuran Dosage

Taken orally with or without food. Can be taken with meals if it causes stomach upset.

Available forms: 50mg oral tablets, 50mg injection solution

Usage: Avoid crowded spaces with sick people. Inform your doctor about any signs of infection. Be careful to avoid injuries or bleeding. Inform all healthcare providers that you are using this medication before any procedures. Report any concerning side effects to your doctor promptly. Use proper sun protection – it may increase skin cancer risk. Inform your doctor about any concerning symptoms or enzyme deficiencies. Use effective contraception during treatment.

Imuran Manufacturer

GlaxoSmithKline (GSK)



Autoimmune diseases, rheumatoid arthritis, ulcerative colitis, organ transplant rejection, Imuran, azathioprine