Fluxopride 5 mg Fast Dissolving in Mouth Tablets

Mozaprid (the active ingredient in Fluxopride tablets) works by helping to move food in the stomach through (the gut) the digestive tract more quickly, and this helps to stop the feeling of nausea.

Fluxopride tablets can also be used in the treatment of conditions that result from delayed emptying of food from the stomach, which causes the following symptoms: feeling of fullness (during or after eating), flatulence, bloating, belching, nausea, heartburn and stomach pain.

Instructions for use

Fluxopride tablets should be taken exactly according to the doses prescribed by the attending physician. The dose of Fluxopride tablets for adults and youth over 16 years is 5 mg of mosapride (one tablet) up to three times a day.

No more than three doses should be taken in any 24 hour period.

The dose of Fluxopride tablets should be taken about half an hour before meals, and it should be noted that taking Fluxopride tablets after a meal does not reduce its effectiveness, but only delays its effect and may take longer to have an effect.

Fluxopride tablets should only be taken for a short period of time. It is recommended that you stop taking Fluxopride if there is no improvement in your symptoms within two weeks of starting treatment.

Fluxopride – Frequently Asked Questions

When does Fluxopride start to work?

Fluxopride is usually prescribed to adults at a dose of 5 mg (one tablet) three times a day, 15 minutes before meals. Fluxopride usually begins to work about 30 to 60 minutes after taking a dose.

It is recommended that you take Fluxopride for the shortest possible time and at the lowest dose that control your symptoms. Usually your doctor will advise you to take Fluxopride for up to 1 or 2 weeks.

Is Fluxopride safe ?

For most people, it is considered safe to take Fluxopride. However, if you have heart problems or are taking other medications, you should first check with your doctor to see if this medication is appropriate.

Generally, the lowest appropriate dose should be used for the shortest possible period of time.

Does Fluxopride cause drowsiness?

Drowsiness is a possible side effect of Fluxopride. Drowsiness can affect between 1 in 10 people who take Fluxopride. It should also be noted that 1 in 100 people taking Fluxopride will experience dry mouth, which is a common side effect of Fluxopride.

Can I take Fluxopride with omeprazole?

Fluxopride in combination with omeprazole can achieve an ideal effect in the treatment of gastritis, which is of great significance in the treatment of patients with gasteritis or peptic ulcer. Omeprazole in combination with Fluxopride can give full play to the gastric acid-suppressing effects of omeprazole as well as the antiemetic and gastric emptying effect of Fluxopride.

Can you take Fluxopride before bed?

Your doctor may ask you to take Fluxopride for a maximum of 1 or 2 weeks. It is best to take Fluxopride 15 to 30 minutes before meals and if necessary an increased dose can be taken at bedtime.

Can I take Fluxopride for long period of time?

Research indicates that the risks of Fluxopride are greater at higher doses or when used for a longer period, therefore it is recommended to use this drug in low doses and for short periods (about two weeks) to treat symptoms of digestive disorders. Treatment should be discontinued if there is no improvement in symptoms after 2 weeks of starting treatment.

Does Fluxopride cause flatulence?

No, Fluxopride does not cause flatulence. Fluxopride is used to relieve symptoms of excessive satiety, nausea and flatulence, and is sometimes prescribed for stomach upset and heartburn after meals.

Is Fluxopride safe for pregnant and breastfeeding women?

Administration of mosaprid (the active ingredient in Fluxopride) to animals at doses up to 80 mg/kg/day does not cause teratogenic effects. However, like most medicines, Fluxopride should be used, especially during the first trimester of pregnancy, only if justified by the expected therapeutic benefit. Simply pregnant women can take Fluxopride if justified and after consulting the  physician.

It is not known whether taking Fluxopride during breast-feeding is harmful to a nursing infant, so breast-feeding is not recommended for mothers taking Fluxopride, unless the expected benefits outweigh any potential risks.

Composition

  • Active ingredient: Mosapride citrate 5 mg.
  • Trade name: Fluxopride 5 mg tablets
  • Generic name: Mosapride citrate
  • Form: Fast Dissolving in Mouth Tablet

Indications

gastrointestinal symptoms associated with functional dyspepsia , such as:

  • chronic gastritis.
  • heartburn,
  • nausea/vomiting.

Dosage

Adults: 15 mg administrated daily in 3 divided oral doses before or after meals. (one tablet Fluxopride three times per day).

Administration: Fluxopride dose Should be taken with food (take before or after meals).

Special precautions: If any improvement of gastrointestinal symptoms is not observed after the administration for a given period of time (usually for 2 weeks), Fluxopride should not be administered aimlessly for a long period of time.

Use in pregnancy and lactation: Safety of Fluxopride in pregnant women has not been established, it should not be used in pregnant women, women who may possibly be pregnant.

During Pregnancy, Fluxopride can only be used if the expected therapeutic benefits outweigh the possible risks associated with the treatment.

Animal (rat) experiments have shown that drug is excreted in breast milk.

Administration of Fluxopride to nursing mothers should be avoided. If administration is essential, nursing mothers should discontinue breastfeeding during the treatment.

Use in children: Safety of drug in children has not been established (no clinical experience).

Use in the elderly: Since the physiological function in the kidneys and liver are generally reduced in the elderly patients, Fluxopride should be administered with care by monitoring patients’ condition. If any adverse reactions are found, appropriate measures eg, reducing the dose (eg, to 7.5 mg/day) should be given.

Side effects

Adverse reactions were found in 40 of 998 cases (4%) in clinical trials. The main adverse reactions were

  • diarrhea/loose stools (1.8%),
  • dry mouth (0.5%),
  • malaise (0.3%),

Abnormal clinical laboratory test values were observed in 30 of 792 cases (3.8%), which were mainly:

  • eosinophilia (1.1%),
  • elevations of triglyceride (1%),
  • AST (GOT), ALT (GPT), and ALP (0.4% each) (at the time of approval).

Clinically Significant Adverse Reactions: 

Fulminant hepatitis, hepatic dysfunction and jaundice (<0.1%, each). Since fulminant hepatitis, serious hepatic dysfunction accompanied with marked elevations of AST(GOT), ALT (GPT) and jaundice may occur, and the patient should be monitored carefully as some of these reactions were fatal.

If any abnormalities are found, discontinue the administration immediately and give appropriate measures.

Drug Interactions

Gasmove should be administered with care when coadministered with the following drugs:

Anticholinergic agents eg, atropine sulfate and butylscopolamine bromide, etc. There is a possibility that the effect of Fluxopride may be attenuated.

Therefore, in case of the concomitant use of anticholinergic agents, precautions such as taking the drugs at intervals should be taken.

Mechanism and Risk Factors: As gastroprokinetic effect of mosapride citrate is exerted by activation of the cholinergic nerves, concomitant use of anticholinergic agents may decrease the effect of Fluxopride.

Warning

patients with rare hereditary problems of galactose intolerance, the Lapp lactose deficiency or glucose- galactose malabsorption should not take this medicine.

Patient Information leaflet

For Arabic patient information about Fluxopride – click the link here

فلاكسوبرايد (موسابرايد سيتريت): الاستخدامات، الجرعة، الآثار الجانبية، التفاعلات

  • Storage: Store at room temperature not exceeding 30°C in dry place.
  • Pack: Cartoon box containing 2 Alu/Pvc strips each of 10 tablets

فلاكسوبرايد ٥ ميليجرام أقراص قابلة للذوبان بالفم – علاج اضطرابات الجهاز الهضمي

Product reference code: A03FA09