Excedrin: Your Companion for Temporary Pain Relief

When it comes to temporary pain relief, Excedrin is a trusted brand that combines three active ingredients: acetaminophen, aspirin, and caffeine. This powerful combination offers effective relief for a variety of common ailments. Let’s explore the indications, dosage, warnings, precautions, and other important information about Excedrin.

Active Ingredients

Each tablet of Excedrin contains the following active ingredients:

  • Acetaminophen: 250 mg
  • Aspirin: 250 mg
  • Caffeine: 65 mg


Excedrin is indicated for the temporary relief of pain associated with the following conditions:

  • Headaches
  • Sinusitis
  • Colds
  • Migraine headaches
  • Muscular aches
  • Pre-menstrual and menstrual cramps
  • Toothache
  • Minor pain from arthritis

Dosage and Administration

To effectively manage pain, it is important to follow the recommended dosage and administration guidelines for Excedrin:

  • For adults: Take 2 tablets with a glass of water every 6 hours while symptoms persist. Do not exceed 8 tablets in 24 hours, unless directed by a doctor.
  • For children under 12 years of age: Consult a doctor before use.

Warnings and Precautions

Before using Excedrin, it is important to be aware of the following warnings and precautions:

  • Pregnancy and breastfeeding: If you are pregnant or nursing, seek the advice of a healthcare professional before using this product. Note that aspirin should not be used during the last three months of pregnancy unless specifically directed by a doctor.
  • Consult a doctor: If pain persists for more than 10 days or if fever persists for more than 3 days, it is important to consult a doctor.
  • Allergy and medical conditions: Do not take this product if you are allergic to aspirin, acetaminophen, or any other pain reliever or fever reducer. Additionally, avoid using this product if you have asthma, high blood pressure, heart disease, kidney disease, or if you are taking diuretics or prescription drugs for anticoagulation, diabetes, gout, or arthritis, unless directed by a doctor.
  • Gastrointestinal risk: Excedrin contains NSAIDs, which may increase the risk of serious gastrointestinal adverse events and stomach bleeding. This risk is particularly significant for elderly patients, those with stomach ulcers or bleeding problems, individuals taking blood thinning medications, steroid drugs, or other drugs containing NSAIDs. It is important to avoid consuming more than three alcoholic drinks per day while using the product and to take the medication for the prescribed duration.
  • Increased bleeding tendency: This medication may increase the risk of bleeding during and after surgical operations, including minor procedures such as dental extractions, due to its inhibitory effect on platelet aggregation.
  • Liver warning: Excedrin contains acetaminophen, which may cause severe liver damage if taken in excessive amounts (more than 8 tablets in 24 hours) or if taken with other drugs containing acetaminophen or in combination with excessive alcohol consumption.
  • Reye syndrome: Children and teenagers should not use this medicine for chickenpox or flu symptoms without consulting a doctor due to the rare but serious risk of Reye syndrome associated with aspirin use in these cases.
  • Ringing in the ears or loss of hearing: If these symptoms occur, it is important to consult a doctor before taking any more of this product.
  • Caffeine warning: The recommended dose of Excedrin contains about as much caffeine as a cup of coffee. Limit the use of other caffeine-containing medications, foods, or beverages while taking this product, as excessive caffeine consumption may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeats.


In the event of an overdose, it is important to seek immediate professional medical help.

How Supplied

Excedrin is available in boxes containing 10 or 20 film-coated tablets.


To maintain the quality and effectiveness of the medication, store Excedrin below 30°C and protect it from light.

In Conclusion

Excedrin is a reliable choice for temporary pain relief, offering a powerful combination of acetaminophen, aspirin, and caffeine. Whether you’re dealing with headaches, sinusitis, or muscular aches, Excedrin can provide the relief you need. However, it is important to heed the warnings, precautions, and dosage recommendations associated with this medication. Always consult your healthcare professional if you have any questions or concerns, and remember to store all medications out of the reach of children.

Disclaimer: This blog post is for informational purposes only and should not be considered a substitute for professional medical advice. Always consult your healthcare provider before starting any medication or treatment.