DANTRELAX 25MG 30CAP: A Muscle Relaxant for Various Conditions

Dantrelax capsules, containing 25 mg of Dantrolene Sodium, are a pharmaceutical solution commonly prescribed to address muscle spasms and muscle-related pain due to various neurological and muscular conditions. In this article, we will explore the composition, properties, indications, dosage, potential side effects, contraindications, precautions, and storage details associated with Dantrelax.


Composition

Each Dantrelax capsule contains 25 mg of Dantrolene Sodium.


Properties

Dantrelax is a skeletal muscle relaxant that acts directly on muscle fibers. It achieves muscle relaxation by preventing the release of calcium from the sarcoplasmic reticulum and targeting the muscle’s nerve-muscle junction. This mechanism makes it effective for managing muscle spasms and related pain.


Pharmacokinetics

The pharmacokinetics of Dantrelax involve slow but nearly complete absorption, with the drug concentration in the blood correlating with the dose administered. The strength and duration of muscle relaxation depend on the dose and blood concentration of the drug. It has a half-life of approximately nine hours and undergoes metabolism primarily in the liver, with similar patterns in both adults and children.


Indications

Dantrelax is prescribed to alleviate painful muscle spasms resulting from various neurological and muscular conditions, including:

  • Spinal cord injuries
  • Cerebral palsy
  • Injuries associated with brain arteries
  • Multiple sclerosis
  • Muscular spasms accompanied by pain
  • Muscle contractions due to injuries
  • Lower back pain
  • Skeletal muscle contractions for various reasons

Dosage

For adults, treatment with Dantrelax usually begins with one capsule (25 mg) per day and may gradually increase at weekly intervals, with a maximum dosage of 100 mg four times daily.

For children (above five years of age), treatment typically commences with a dose of 0.5 mg per kilogram of the child’s weight, taken once daily and potentially increased gradually to 1 mg per kilogram three times a day.


Contraindications

Dantrelax should not be used in individuals with severe liver impairment or a hypersensitivity to the drug.


Precautions

Use of Dantrelax should be cautious in patients with severe liver, respiratory, or heart conditions. Caution should also be exercised when combining Dantrelax with sedatives. The safe long-term use of Dantrelax in children under the age of five is not established.


Side Effects

Some side effects may occur during Dantrelax use, including dizziness, nausea, weakness, and diarrhea. These symptoms are more likely to appear at the beginning of treatment but can often be minimized by starting with a small dose and gradually titrating to the optimal dosage.


Packaging and Storage

Dantrelax is available in a cardboard box containing either 20 capsules or 2 strips, with each strip containing 10 capsules. It should be stored at temperatures below 30°C, and, like all medications, kept out of the reach of children.


In summary, Dantrelax is a muscle relaxant suitable for addressing muscle spasms and pain associated with a range of neurological and muscular conditions. However, patients should follow their healthcare provider’s guidance for appropriate dosages and potential side effects, and it should be stored under proper conditions to maintain its efficacy.

إنتاج: الدواء من إنتاج شركة كيميفارم للصناعات الدوائية في مدينة 6 أكتوبر – مصر.

دانتريلاكس لعلاج تقلص العضلات الهيكلية

جرعة دانتريلاكس للبالغين: يبدأ العلاج بكبسولة واحدة يومياً (25 مجم) وقد تزداد تدريجاً على فترات أسبوعية، بحد أقصى 100 مجم أربع مرات يومياً.