Each tablet contains: carbamazepine 200 mg.
As an anti-epileptic agent, Carbatol® has a beneficial effect on partial seizures ( simple & complex) with and without secondary generalization; generalized tonic-clonic seizures (grandmal), as well as combination of these types of epilepsy.
As a neurotropic agent, Carbatol® is effective in a number of neurological disorders, e.g. it prevents paroxysmal attacks of pain in idiopathic trigeminal neuralgia.
In diabetes insipidus centralis, Carbatol® reduces the urinary volume and relieves the feeling of thirst.
As a psychotropic agent, Carbatol® proved to have clinical efficacy in affective disorders, i.e. as treatment of mania as well as for the prevention of manic depressive (bipolar) disorders when given either as monotherapy or in combination with neuroleptics, antidepressants, or lithium.
In alcohol-withdrawal syndrome, Carbatol® improves withdrawal symptoms, e.g. hyperexcitability, tremor, impaired gait.
Certain types of adverse reaction occur occasionally or frequently, e.g., CNS adverse reactions (dizziness, headache, ataxia, drowsiness, fatigue, diplopia); gastrointestinal disturbances (nausea, vomiting), as well as allergic skin reactions.
The tablets may be taken during , after, or between meals with a little liquid.
1-Dosage in Epilepsy
Treatment should be initiated with a low daily dosage, to be slowly increased until an optimal effect is obtained. After obtaining adequate seizure control, dosage may be reduced very gradually to the minimum effective level.
Initially, 100-200 mg once or twice daily; slowly raise the dosage until –generally at 400 mg 2-3 times daily, an optimum response is obtained. In some patients, 1600 mg or even 2000 mg daily may be appropriate.
Children dosage – Oral forms:
- 6-10 years of age 400-600 mg daily.
- 11-15 years of age 600-1000 mg daily.
2-Dosage in Trigeminal neuralgia
The initial dosage of 200-400 mg daily until freedom from pain is achieved (normally at 200 mg 3-4 times daily).
Then gradually reduce the dosage to the lowest possible maintenance level.
In elderly patients, an initial dose of 100 mg twice daily is recommended.
3-Dosage in Alcohol-withdrawal syndrome
Average dosage : 200 mg 3 times daily. In severe cases it can be raised during the first few days (e.g., to 400 mg 3 times daily),
4-Dosage in Diabetes insipidus centralis
Average dosage for adults: 200 mg 2-3 times daily.
5-Dosage in Painful diabetic neuropathy
200 mg 2-4 times daily.
6-Dosage in Mania and prophylactic treatment in manic-depressive (bipolar) disorders
Dosage range: about 400-1600 mg daily, the usual dosage being 400-600 mg daily given in 2-3 fractional doses.
Carbatol®: Strips of 10 tablets (200 mg) in packs of 2 strips.
Keep all medicaments out of reach of children
Product of: AMOUN PHARMACEUTICAL CO. El-Obour City, Cairo, Egypt. ATC Code: N03AF01