Active ingredient: Biperiden hydrochloride
1 tablet contains 2 mg of Biperiden hydrochlonde
Mode of action
Biperiden is a centrally-acting anticholinergic which owes its therapeutic action in parkinsonian syndrome and drug-induced extrapyramidal symptoms to competitive binding to muscarinic receptors especially the M1 receptors.
Indications and usage
- As an adjunct in the therapy of all forms of parkinsonism (idiopathic, postencephalitic, arteriosclerotic).
- Control of extrapyramidal disorders secondary to neuroleptic drug therapy (e.g. phenothiazines).
Dosage and administration
- Drug-Induced Extrapyramidal symptoms : Oral: one tablet one to three times daily.
- Parkinsons Disease: Oral, the usual beginning dose is one tablet three or four times daily. The dosage should be individualized with the dose titrated upward to a maximum of 8 tablets (16 mg ) per 24 hours.
Biperiden – FAQs
Q.1 – Is Biperiden hypnotic?
Biperiden is not a hypnotic drug, but it may cause drowsiness and a feeling of sleepless as a side effect, especially at the beginning of use.
You should not take this medication on your own. Biperiden should not be prescribed solely to treat sleep disorders and insomnia.
Biperiden can sometimes be prescribed along with other medications to treat certain mental and neurological disorders that can cause sleep problems or disturbances.
Biperiden is not approved as a hypnotic drug, this drug is only officially approved for Parkinson’s disease.
Many people abuse this drug, and use it for its hypnotic properties, and this is considered abuse that can lead to serious health consequences.
Q.2 – Is Biperiden a narcotic drug?
No, Biperiden is not a narcotic, and it is not classified as a narcotic drug (medicines that affect the mental and neurological state). However, some may abuse it and take it in high doses due to its hypnotic and narcotic properties.
We must draw the reader’s attention that taking Biperiden in large doses will not cause you to feel high as with narcotic drugs, but it may cause you to feel drowsy and sleepy, and may cause you serious health problems as a result of excessive doses.
Do not take Biperiden on your own, stick to the dose and duration of treatment prescribed by your doctor, and do not repeat this medication without checking with your doctor.
Q.3 – Is treatment with Biperiden for a long time addictive?
Biperiden (the active ingredient in Biperiden) is not an addictive drug, if the patient sticks to the prescribed dosage.
Some patients abuse this drug, by taking high doses, this makes the patient feel dependent.
Is it possible to stop taking Biperiden after getting used to it? The answer is simply: Yes, and the problems that the patient will face will not exceed a few days, the withdrawal symptoms can be easily overcome.
Q.4- How do I stop Biperiden?
You should not stop taking Biperiden on your own, even if you feel better.
Important tip: Do not stop taking the doses that your doctor has prescribed for you, just consult your doctor before stopping or reducing the dose of Biperiden.
If your doctor decides to stop the medication or reduce the dose, he will do so gradually.
Q.5 – What are the effects of stopping the drug Biperiden?
VERY IMPORTANT: Do not stop taking Biperiden, even if you feel better, until after consulting your doctor.
Usually, the doctor advises you to gradually reduce the dose over a period of two weeks or more, until it stops completely.
You may experience some symptoms when you stop taking Biperiden, and these symptoms are as follows:
- Inability to sleep.
- Daydream .
- a feeling of discomfort;
- feeling nauseous
Mostly these symptoms last for a period ranging from 3 days to a maximum of a week.
Q.6 – Does Biperiden cause weight gain?
Weight gain is a common side effect of Biperiden, since it can lead to an increase in appetite. People who are more likely to be overweight, such as a family with a history of obesity, can gain weight. We recommend that you follow a diet moderate in calorie content during the period of treatment with Biperiden, to avoid significant weight gain.
Q.7 – Does Biperiden affect sexual function in men?
Yes, sexual problems are one of the possible side effects of Biperiden. This drug may cause a delay in ejaculation or problems in erection, and sometimes affect sexual desire, where the patient feels an unusual decrease or increase in sexual desire.
If you experience any problems with sexual function during the period of treatment with Biperiden, do not stop the medication and do not reduce your dose on your own, just see your doctor, and he will decide what is necessary for you.
- Hypersensitivity to biperiden.
- Narrow angle glaucoma
- Bowel obstruction
- Prostatic hypertrophy.
Isolated instances of mental confusion, euphoria, agitation and disturbed behaviour have been reported in susceptible patients.
Also the central anticholinergic syndrome can occur. As an adverse reaction to properly prescribed anticholinergic medication, although it is more frequently due to overdosage.
It may also result from concomitant administration of an anticholinergic agent and a drug that has secondary anticholinergic actions.
Cautions should be observed in patients with manifest glaucoma, though no prohibitive rise in intraocular pressure has been noted following oral administration.
Patients with prostatism, epilepsy or cardiac arrhythmia should be given this drug with caution.
Occasionally, drowsiness may occur, and patients who drive a car or operate any other potentially dangerous machinery should be warned of this central nervous system, the consumption of alcohol should be avoided during Biperiden therapy.
Drug interaction: the central anticholinergic syndrome can occur when anticholinergic agents such as Biperiden are administered concomitantly with drugs that have secondary anticholinergic action, e.g., certain narcotic analgesics such as meperidine, the phenothiazines and other antipsychotics, tricyclic antidepressants certain antiarrhythmics such as the quinidine salts and antihistaminics.
CNS effects may manifest as fatigue, dizziness and drowsiness and especially at higher dosages restlessness, agitation, anxiety, confusing, euphoria.
Occasionally impairment of memory and in rare cases delirium and hallucinations, nervosity headache and insomnia.
Dyskinesia, ataxia, muscle twitching and speech impairment have sometimes been observed.
Stimulation of the CNS is common in patients with impaired cerebral function and may require dose reduction peripheral side effects include dry mouth rarely swelling of the salivary glands accomodation difficulties.
Mydriasis accompanied by photophobia, hypohidrosis, constipation, gastric symptoms, nausea. tachycardia and rarely bradycardia.
Occasionally difficult urination especially in patients with prostatic hypertrophy (dose reduction is recommended) and more rarely retention of urine (antidote : carbachol).
Narrow angle glaucoma may occur.
Furthermore hypersensitivity and isolated cases of allergic reactions have been reported.
Product reference code: N04AA02.