Binorec Tablets

Composition

Each tablet contain: Bismuth sub-citrate 120 mg.

Properties

Binorec through its colloidal bismuth sub-citrate content enhances mucosal defense and forms a protective layer over the ulcer crater, allowing ulcer healing. Also, colloidal bismuth sub-citrate possesses bactericidal activity against H. pylori. Resistance to colloidal bismuth sub-citrate has not been observed.

Indications

  • Ulcer healing.
  • Lower relapse rates of ulcer.
  • It is essential to be given as a dual or triple therapy for H. pylori eradication in order to prevent the emergence of mutants resistant to certain antibiotics.

Dosage & Administration

2 tablets twice daily.

Contra-Indications

Hypersensitivity to bismuth salts & not recommended during pregnancy.

Drug – Drug interactions

  • Concomitant administration of antacids, milk, food and H2-receptor antagonists may impair the efficacy of the drug.
  • Nausea, diarrhea and burning of the mouth & throat during triple therapy with amoxycillin & metro nidazole.
  • The absorption of iron as well as tetracycline may be decreased as a result of chelate formation.

Side Effects

  • Increases in hemoglobin levels.
  • Mild reduction in diastolic blood pressure.
  • Headache, Dizziness.
  • Bismuth encephalopathy upon high doses & long treatment.
  • Fecal discoloration.
  • Patients with renal impairment show accumulation of bismuth leading to encephalopathy.

Packing

Box of 60 tablets (5 strips of 12 tablets each).

Binorec Tablets is a product of Adwia Pharmaceuticals , Egypt