AZITRO 500 mg: Your Comprehensive Guide

When it comes to taking medication, understanding the basics is crucial for your health and well-being. In this guide, we’ll delve into the details of AZITRO 500 mg, a film-coated tablet prescribed for a variety of infections. Whether you’re new to this medication or just need a refresher, we’ve got you covered.

What is AZITRO and What is it Used For?

AZITRO 500 mg is a white, oblong, and odorless film-coated tablet. The active ingredient in each tablet is azithromycin dihydrate, equivalent to 500 mg of azithromycin. AZITRO belongs to a group of antibiotics known as macrolides, and it is employed in the treatment of infections caused by certain bacteria and microorganisms. These infections include:

  • Chest, throat, and nasal infections (inflammation of bronchi, lungs, and sinusitis, among others).
  • Tonsil infections due to Streptococcus pyogenes (tonsillitis), especially when penicillin allergy is present.
  • Acute ear infections (acute otitis media).
  • Skin and soft tissue infections (abscesses or boils).
  • Sexually transmitted diseases caused by Chlamydia.
  • Soft tissue ulcers resulting from Haemophilus ducreyi and uncomplicated genital infections caused by Neisseria gonorrhoeae when no other accompanying infections are present.

Before Taking AZITRO

Before starting your AZITRO regimen, it’s essential to be aware of certain factors. Here are some key points to consider:

Do NOT Take AZITRO If:

  • You are allergic to AZITRO or any other macrolide antibiotic, such as erythromycin or clarithromycin.
  • You have liver problems.
  • You are using ergot derivatives, typically used to treat migraines.

Take Special Care with AZITRO If:

  • You have kidney problems.
  • You have heart disease.
  • You have acquired an infection from the community.
  • You have been diagnosed or suspected of having bacteria or bacterial toxins in your blood.
  • You are bedridden.
  • You are elderly or in a weakened state.
  • You have other serious health problems.
  • You have liver disease.
  • You develop diarrhea.

Pregnant or planning to get pregnant? Consult your doctor before taking AZITRO. It should only be used during pregnancy when clearly needed.

Breastfeeding? Consult your healthcare provider before taking AZITRO, as it is not known whether it is excreted in human milk.

Taking AZITRO with Food and Drink

AZITRO should be taken either 1 hour before or 2 hours after meals.

Interaction with Other Medicines

Inform your doctor if you are taking other medicines, especially:

  • Ergot or ergotamine.
  • Warfarin or any similar medicine to prevent blood clots.
  • Cyclosporine (used to suppress the immune system).
  • Digoxin (used to treat heart failure).
  • Theophylline (used to treat asthma).
  • Nelfinavir (used to treat HIV infection).

If you use antacids for indigestion, take AZITRO 1 hour before or 2 hours after taking antacids. Also, be aware that a low number of neutrophils may occur when AZITRO is taken alongside rifabutin.

How to Take AZITRO

AZITRO should be taken as a single daily dose. The dosage varies depending on the condition being treated:

  • For sexually transmitted diseases due to Chlamydia, Haemophilus ducreyi, or susceptible Neisseria gonorrhoeae, the recommended dose is 1000 mg as a single oral dose.
  • For all other indications, the total dosage is 1500 mg, taken as 500 mg daily for 3 days.
  • For tonsillitis/pharyngitis due to S. pyogenes, the dosage is 500 mg on day 1 and 250 mg daily on days 2 through 5, with a total duration of 5 days.

Special Considerations by Age Group

Children: For pediatric patients weighing over 45 kg, adult doses are administered for all indications except tonsillitis/pharyngitis. For the latter, the recommended dosage is 500 mg on day 1 and 250 mg daily on days 2 through 5, with a total treatment duration of 5 days. Oral suspension forms are available for pediatric patients weighing less than 45 kg. AZITRO is not recommended for infants younger than 6 months of age.

Elderly: Adult doses are administered in elderly patients.

Special Conditions

  • Kidney Failure: No dosage adjustment is recommended for subjects with mild to moderate kidney failure, but caution should be exercised in cases of severe kidney failure.
  • Liver Failure: The same doses may be administered to patients with mild to moderate liver failure, as with normal liver function. However, it should not be used in cases of severe liver failure.

Remember, it’s crucial to follow your doctor’s advice on dosing and duration of treatment. If you ever feel that the effect of AZITRO is too strong or too weak, don’t hesitate to talk to your healthcare provider.

Possible Side Effects

As with any medication, AZITRO may cause side effects, although they are generally rare. If you experience any of the following symptoms, contact your healthcare provider immediately:

  • Irregular heartbeat, shortness of breath, dizziness, or fainting.
  • Sudden wheezing.
  • Difficulty breathing.
  • Swelling of eyelids, face, or lips.
  • Rash or itching, especially if it affects your whole body.

Common side effects, which tend to diminish as your body adjusts to the medicine, include:

  • Diarrhea.
  • Stomach cramps.
  • Nausea.
  • Flatulence.
  • Headache and drowsiness.
  • Pins and needles or numbness.
  • Taste disturbance and loss of appetite.
  • Visual disturbances and deafness.
  • Vomiting, indigestion, and rash.

Remember, side effects are classified by frequency:

  • Very common: Affects at least 1 in 10 patients.
  • Common: Affects 1 to 10 patients in 100.
  • Uncommon: Affects 1 to 10 patients in 1000.
  • Rare: Affects 1 to 10 patients in 10,000.
  • Very rare: Affects less than 1 patient in 10,000.
  • Unknown: Cannot be estimated from the available data.

Uncommon and rare side effects can include yeast infections, allergic reactions, skin reactions, nervousness, sleep-related issues, liver inflammation, chest pain, and more. If you experience any unusual symptoms, it’s vital to inform your healthcare provider.

How to Store AZITRO

To ensure the potency and safety of your medication, follow these storage guidelines:

  • Keep AZITRO out of reach and sight of children.
  • Store in the original package.
  • Keep it at room temperature below 25°C.
  • Use it within the indicated expiry date.
  • Do not dispose of AZITRO through wastewater or household waste. Consult your pharmacist for proper disposal methods.

This comprehensive guide aims to provide you with essential information about AZITRO 500 mg. While taking any medication, it’s crucial to follow your healthcare provider’s guidance for your specific condition. If you have any questions or concerns, don’t hesitate to reach out to your doctor or pharmacist. Your health is a top priority, and understanding your medication is a significant step toward maintaining it.

Disclaimer: This article serves as an informative guide and is not a substitute for professional medical advice. Always consult with your healthcare provider for personalized guidance on your medication and health.


Please refrain from disposing of any medications in wastewater or household waste. Consult your pharmacist for guidance on the proper disposal of unused medicines. These actions are essential to safeguard the environment.

Marketing Authorization Holder: DEVA Holding A.Ş. Address: Halkalı Merkez Mah. Basın Ekspres Cad. No: 1, 34303 Küçükçekmece – ISTANBUL, TURKEY

Manufacturing Site: DEVA Holding A.Ş. Address: Çerkezköy Organize Sanayi Bölgesi, Karaağaç Mah. Atatürk Cad., No: 32, Kapaklı – TEKIRDAG, TURKEY