Avelox: Your Guide to Safe and Effective Treatment

Are you about to begin a course of Avelox (Moxifloxacin) for the treatment of bacterial infections? It’s essential to have all the facts before starting any medication. In this article, we’ll provide you with a detailed but easy-to-understand guide on Avelox, what it’s used for, what you need to know before taking it, how to use it, possible side effects, storage instructions, and more. Whether you’re a patient, caregiver, or simply curious, this information will help you make informed decisions about this medication.

What Is Avelox and What Is It Used For?

Avelox contains the active substance Moxifloxacin, which belongs to a group of antibiotics called fluoroquinolones. This medication works by killing bacteria that cause infections when these infections are susceptible to Moxifloxacin. Avelox is primarily used in adults to treat the following bacterial infections:

  • Infection of the lungs (pneumonia) acquired outside the hospital.
  • Infections of the skin and soft tissues.

What You Need to Know Before Taking Avelox

Before you begin your treatment with Avelox, there are essential factors to consider:

Do Not Use Avelox If:

  • You are allergic to Moxifloxacin, other quinolone antibiotics, or any of the other ingredients in Avelox.
  • You are pregnant or breastfeeding.
  • You are under 18 years of age.
  • You have a history of tendon disease related to quinolone antibiotics.
  • You have a history of abnormal heart rhythms, weak heart, or take medications affecting heart rhythms.
  • You have severe liver disease or high liver enzyme levels.

Warnings and Precautions

Before starting Avelox, talk to your doctor if you’ve had any serious adverse reactions to quinolone antibiotics in the past. Additionally, consult your healthcare provider if you have:

  • Heart issues, especially if you are female or elderly.
  • A history of skin rash, blistering, or mouth sores after taking Moxifloxacin.
  • Epilepsy or a condition prone to convulsions.
  • Mental health problems.
  • Myasthenia gravis.
  • Aortic aneurysm or aortic dissection.
  • A family history of aortic aneurysm, aortic dissection, or other risk factors.
  • Diabetes.
  • Glucose-6-phosphate dehydrogenase deficiency.
  • Kidney problems.
  • Vision problems.
  • Skin sensitivity to sunlight or UV light.
  • Sequential intravenous/oral Avelox treatment for lung infections acquired outside the hospital.
  • Burns, deep tissue infections, or diabetic foot infections with osteomyelitis.

Avelox and Other Medications

When using Avelox, avoid medications that can alter your heart rhythm. Also, be cautious if you’re taking medications that affect your blood potassium levels, and inform your doctor if you’re using oral anti-coagulants like warfarin.

Avelox and Food/Drink

The effectiveness of Avelox is not influenced by food, including dairy products.

Pregnancy, Breastfeeding, and Fertility

Avelox should not be used during pregnancy or breastfeeding. If you’re pregnant, breastfeeding, planning to have a baby, or unsure about your fertility, consult your healthcare provider for advice.

Driving and Using Machines

Avelox can cause dizziness, transient vision loss, or fainting. If you experience these side effects, avoid driving or operating machinery.

Avelox Contains Sodium

Each bottle of Avelox contains sodium. Be aware of your sodium intake, especially if you’re on a low-sodium diet.

How to Use Avelox

Avelox is administered intravenously by a healthcare professional. The standard adult dose is one bottle once daily, given over a 60-minute infusion. The duration of treatment depends on the type of infection and your response to the medication.

It’s crucial to complete the prescribed course, even if you start feeling better before it ends. Stopping early can lead to incomplete healing and antibiotic resistance.

If you miss a dose or receive more than you should, contact your doctor immediately. You should also consult your healthcare provider if you wish to stop treatment early.

Possible Side Effects

All medications come with potential side effects. Some of the most serious side effects of Avelox include:

  • Fast heart rhythm.
  • Symptoms of liver inflammation.
  • Serious skin rashes.
  • Acute generalised exanthematous pustulosis (AGEP).
  • Syndrome of inappropriate antidiuretic hormone secretion (SIADH).
  • Low blood sugar levels.
  • Inflammation of blood vessels.
  • Allergic reactions.
  • Convulsions.
  • Prolonged and potentially irreversible side effects.

Less severe, more common side effects include:

  • Nausea.
  • Diarrhea.
  • Dizziness.
  • Abdominal pain.
  • Headache.
  • Increased liver enzyme levels.
  • Infections by resistant bacteria or fungi.
  • Injection site pain or inflammation.
  • Changes in heart rhythm (ECG) with low blood potassium levels.

Uncommon side effects consist of:

  • Rash.
  • Stomach upset.
  • Changes in taste.
  • Sleep disturbances.
  • Gastrointestinal discomfort.
  • Itching.
  • Dizziness.
  • Sleepiness.
  • Gastrointestinal wind.
  • Changes in heart rhythm (ECG).
  • Impaired liver function.
  • Decreased appetite.
  • Musculoskeletal pain.
  • Sweating.
  • Anxiety.
  • Weakness or tiredness.

Rare side effects include:

  • Muscle twitching.
  • Muscle cramps.
  • Hallucinations.
  • High blood pressure.
  • Swelling.
  • Kidney impairment.
  • Liver inflammation.
  • Inflammation of the mouth.
  • Ringing in the ears.
  • Jaundice.
  • Impaired skin sensation.
  • Abnormal dreams.
  • Concentration difficulties.
  • Difficulty swallowing.
  • Changes in smell.
  • Balance and coordination issues.
  • Memory impairment.
  • Hearing impairment.
  • Increased blood uric acid.
  • Emotional instability.
  • Impaired speech.
  • Fainting.
  • Muscle weakness.

Very rare side effects encompass:

  • Drop in the number of blood cells.
  • Joint inflammation.
  • Abnormal heart rhythms.
  • Increased skin sensitivity.
  • Feeling of self-detachment.
  • Increased blood clotting.
  • Muscle rigidity.
  • Blood cell count reduction (pancytopenia).
  • Vein inflammation.
  • Stomach inflammation.
  • Dehydration.
  • Severe heart rhythm abnormalities.
  • Dry skin.
  • Angina pectoris.

Intravenous treatment may lead to:

  • Increased liver enzyme levels.
  • Severe diarrhea.
  • Fast heart rhythm.
  • Hallucinations.
  • Low blood pressure.
  • Kidney impairment.
  • Kidney failure.
  • Swelling.
  • Convulsions.

There have been very rare cases of long-lasting or permanent side effects associated with quinolone and fluoroquinolone antibiotics. These include tendon inflammations, tendon ruptures, joint pain, pain in the limbs, difficulty in walking, and neurological issues.

If you experience any side effects or worsening symptoms while taking Avelox, contact your healthcare provider immediately.

How to Store Avelox

Keep Avelox out of the reach of children. Do not use the medication after the expiry date. Store it below 30°C (86°F). Protect it from light and moisture, and do not refrigerate.


Do not dispose of medications in wastewater or household waste. Your doctor or pharmacist can provide information on proper disposal.

Additional Information

For further details about Avelox, its use, side effects, and any questions or concerns you may have, consult your healthcare provider or pharmacist. They can provide you with personalized guidance based on your specific health and medical history.

Remember, this article serves as a general guide and does not replace professional medical advice. It’s crucial to consult with your healthcare provider for accurate information regarding your unique health conditions and medication regimen. They can help you make the best decisions regarding your health and well-being.