An Overview of the Pediatric Antibiotic Skyclav 457 Suspension

Skyclav 457 suspension is an antibiotic combination product containing 400mg amoxicillin and 57mg clavulanic acid per 5mL. This post summarizes proper usage instructions, dosing, safety issues, side effects and key details for giving this medication to babies and children.

Appropriate Uses of Skyclav 457 in Kids

Skyclav 457 covers bacterial infections in pediatric patients like:

  • Ear infections
  • Sinus infections
  • Respiratory infections – pneumonia, bronchitis
  • Urinary tract infections
  • Skin infections – wounds, abscesses

The powder is reconstituted with purified water to create an oral suspension with a pleasant strawberry flavor for easier administration in young children who can’t swallow pills.

Understanding the Amoxicillin and Clavulanic Acid Components

Amoxicillin, a penicillin-type antibiotic, stops bacteria from properly forming cell wall outer layers. The added clavulanic acid shields the amoxicillin from common defense enzymes some organisms release, rendering resistance tactics ineffective.

This combination has superior spectrum coverage over amoxicillin alone for more virulent and drug-resistant strains.

Skyclav 457 Suspension Dosing Guidelines

  • All doses determined by body weight in kilograms
  • Usual dose: 25-45mg/kg divided in 2 daily doses
  • Higher dose (severe infections): Up to 70mg/kg daily in 2 doses

Carefully follow medical instructions for your child’s specific required dose amount and properly measure/administer.

Who Should Avoid Taking Skyclav 457?

Do NOT give Skyclav 457 suspension if your child:

  • Is penicillin or amoxicillin allergic – risk of reactions
  • Has liver dysfunction concerns
  • Has infectious mononucleosis
  • Has experienced antibiotic-related jaundice

Use cautiously if your child has underlying kidney problems, gut/bowel disease history, or is concurrently on other medications that require monitoring.

Potential Side Effects of Skyclav 457

  • Diarrhea or vomiting
  • Yeast infections
  • Rash or itching
  • Liver function changes

Promptly report any severe reactions like widespread hives, facial puffiness, breathing issues or unusual bleeding/bruising. Stopping treatment immediately helps manage antibiotic hypersensitivities.

Giving Skyclav 457 Suspension Correctly

  • Shake vigorously before each use
  • Mix dose with a full meal to reduce stomach upset
  • Refrigerate reconstituted bottle, use within 7 days
  • Give every 12 hours, spacing doses evenly
  • Finish all doses as prescribed

What If a Dose is Missed?

Give missed doses as soon as possible, unless almost time for the next scheduled dose. Never double up doses. Contact the pediatrician if concerns arise about lingering or worsening infection symptoms.

Frequently Asked Questions About Skyclav 457

  1. How long does amoxicillin stay in a child’s system?About 12 hours after the final dose, antibiotic levels reduce by half. It takes over 24 hours to fully clear from systemic circulation. Some gut flora changes can persist longer.
  2. Can probiotics help prevent antibiotic associated diarrhea?Yes. Probiotic supplements can help minimize disruption of good protective bowel bacteria, reducing risk for antibiotic-related diarrhea, yeast infections, etc. Discuss options.
  3. Is Skyclav 457 safe for babies under 6 months?No. Skyclav 457 has not been evaluated in infants under 6 months. An alternate pediatric formulation tailored for lower weights in babies under 6 months is recommended instead after medical guidance.
  4. Can my child go to daycare while on antibiotics?Children should avoid school, daycare and public areas for the first 48 hours on new antibiotics in case of a transmissible illness. After showing response and no fever, most kids can return if feeling well enough to participate.
  5. How long should my kid’s ear infection improve after starting Skyclav?Expect noticeable pain relief in 48 hours once antibiotic levels reach therapeutic concentrations. Call the pediatrician if fever spikes, pain worsens or sudden discharge emerges despite compliance with the medication course.
  6. Can my child drink milk while taking Skyclav?Yes, dairy intake does not impact Skyclav effects. Some stomach coating agents occasionally warrant avoidance, but no food or drink interactions exist with amoxicillin formulations. Give doses with food.
  7. When should we switch to the next higher Skyclav strength?If your pediatrician prescribes a higher 70mg/kg daily Skyclav dose for more serious illness, ensure you obtain the new appropriate 457 suspension bottle strength matched to updated weight, NOT pills. Measure carefully.
  8. What color changes are normal for Skyclav after mixing?Expect a creamy white dry powder that reconstitutes into a homogenized pale strawberry-flavored oral suspension. Some settling between doses is expected. Re-agitate before administering.
  9. Can expired Skyclav be used if my prescription ran out?No. Never utilize antibiotic suspensions beyond the manufacturer listed expiration date on packaging. Potency and safety declines over time without proper refrigerated storage. Use a fresh bottle.
  10. Where can I find affordable Skyclav alternatives?Many regional pharmacies offer generic amoxicillin/clavulanate pediatric suspensions quite affordably, especially at higher tier prescription plan levels. Compare pricing and coupons to maximize savings if cost concerns exist.

Follow all medical instructions for properly reconstituting and accurately dosing the tasty Skyclav 457 antibiotic suspension to treat susceptible bacterial illnesses in young pediatric patients. Monitor kids closely for symptoms improvement or medication side effects. Ask pediatricians any other questions.