An Overview of Skypara-500 Suppositories

Skypara-500 suppositories contain the active ingredient acetaminophen (also known as paracetamol), a commonly used medication for reducing fever and relieving pain. This blog post summarizes key details about Skypara-500, including what it’s used for, how to use it properly, side effects to look out for, and other pertinent information.

What is Skypara-500 Used For?

Skypara-500 suppositories are used for:

  • Alleviating mild to moderate pain
  • Lowering elevated body temperature/fever

The medicine works by inhibiting prostaglandin production in the brain, effectively disrupting pain and fever signals.

This medication format in suppository form allows acetaminophen to be absorbed rectally when unable to take oral tablets or liquids. The medicine enters circulation without passing through the digestive system.

Who Can Use Skypara-500?

Skypara-500 suppositories are approved for use in:

  • Children 12 years and older
  • Adults
  • With minimum body weight of 40 kg (88 lbs)

Thus, this particular product would not suitable for smaller pediatric patients. Consult a pharmacist or doctor for advice on age-appropriate acetaminophen formulations.

Skypara-500 Dosage

  • Initial dose: 1-2 suppositories
  • Maximum daily dose:
    • 4 suppositories per day for ages 12-65
    • 3 suppositories per day for over 65
  • At least 4-6 hours should pass between doses

Follow given dosage instructions closely and do not exceed maximums. Doing so can lead to acetaminophen overdose and liver toxicity.

Using Skypara-500 Suppositories

To insert a suppository properly:

  1. Wash hands thoroughly
  2. Remove one foil-wrapped suppository from strip
  3. Lie on side with knees pulled towards chest
  4. Gently insert narrow end of the suppository into the rectum and push inward as far as possible
  5. Remain still for a few minutes before standing to retain the medicine internally long enough to dissolve and absorb

Never take a suppository orally by mouth or swallow. Only use rectally as directed on packaging.

Skypara-500 Warnings and Precautions

  • Avoid in severe liver/kidney dysfunction
  • Those with hypersensitivities should not use
  • May interact with other medicines metabolized by the liver

Inform your doctor before starting if any medical conditions exist or other medications are being taken to prevent complications. Regular lab tests may be ordered to check liver enzymes.

Immediately seek help if overdose symptoms like nausea, abdominal pain or discoloration of skin/eyes occurs while using.

Side Effects of Skypara-500

  • Rectal irritation
  • Rash, facial swelling (allergic reaction)
  • Easy bleeding/bruising (blood disorder)

Discontinue use if severe or persistent reactions develop. Analgesics rarely cause serious harm when used responsibly but side effects warrant attention.

Storage and Expiration

  • Store below 30°C away from moisture/heat
  • Shelf life listed on outer packaging
  • Return expired/unused meds to a pharmacy for proper disposal

Proper storage preserves drug potency and stops environmental contamination from residues entering landfills/waterways improperly.

Frequently Asked Questions About Skypara-500

Below are answers to 10 common questions people have about Skypara-500 suppositories:

  1. Are Skypara-500 suppositories safe for children?No, Skypara-500 is only approved for ages 12 and up weighing at least 40kg. Do not administer to younger pediatric patients. Consult a pediatrician for alternatives.
  2. Can I take acetaminophen tablets while also using Skypara-500?No, do not simultaneously take other drug forms containing acetaminophen like oral tablets or liquids. Overdose can occur. Time any doses appropriately.
  3. How long do Skypara-500 suppositories take to reduce fever?Effects set in within 30-60 minutes after rectal insertion. Fever should subside within a few hours. If not, consult your doctor.
  4. Can I use Skypara-500 while pregnant or nursing?Use with caution. Discuss risks/benefits with your OB-GYN or pediatrician first. Stop immediately if complications arise for mom or baby.
  5. Do Skypara-500 suppositories expire?Yes, check the expiry date before using. Effectiveness declines after the listed expiration timestamp. Properly dispose of expired meds rather than using.
  6. Why insert Skypara suppositories instead of taking acetaminophen orally?The rectal route allows medicine absorption without relying on oral intake, providing fever/pain relief when unable to swallow or keep down oral drugs.
  7. How often can I use Skypara-500 suppositories per day?Ages 12-65 can use up to 4 suppositories per 24 hours. Over 65 is limited to 3 per day. Carefully space at least 4-6 hours between doses.
  8. Can I cut Skypara-500 suppositories in half to reduce the dose?No. Never break, crush, chew or divide suppositories. Doing so risks improper dosing and rectal irritation. Use intact as packaged.
  9. Where exactly should Skypara-500 suppositories be inserted?Insert the tapered end about 2-3 inches into the rectal canal while lying on your side. Pushing inward as far as comfortable retains the medicine best.
  10. Is acetaminophen safe for long-term pain treatment?No. Regular use beyond a few days to weeks can cause hepatic injury and rebound pain. Evaluate alternate pain relief options with your doctor.


When oral acetaminophen is not ideal or possible for fever and pain scenarios in older kids and adults, Skypara-500 suppositories can be an appropriate short-term treatment choice. Follow all instructions closely, watch for side effects, and avoid overdosing or risky combinations/interactions with these medicated bullet-shaped capsules. Consult a pharmacist or health provider with any other questions.