Amoxi-Denk 500: Your Essential Guide

Amoxi-Denk 500 is an antibiotic that belongs to the penicillin group of medicines, used to treat a wide range of bacterial infections. In this guide, we’ll explore what you need to know about Amoxi-Denk 500, from usage to potential side effects.


Before taking Amoxi-Denk 500, it’s essential to be aware of contraindications:

  • Allergic Reactions: Do not take Amoxi-Denk 500 if you are allergic to amoxicillin, penicillin, or any other ingredients in the medication. Signs of an allergic reaction may include skin itching, swelling of the face, lips, tongue, or difficulties in breathing.


If you have any of the following conditions, consult your doctor or pharmacist before taking Amoxi-Denk 500:

  • Glandular Fever: If you have glandular fever, discuss it with your healthcare provider as the medication may lead to a skin rash.
  • Kidney Problems: If you have kidney problems, your dosage may need adjustment.
  • Urination Issues: Ensure regular urination.

Blood and Urine Tests

If you are undergoing urine tests for glucose or blood tests for liver function or oestriol tests, inform your healthcare provider that you are taking Amoxi-Denk 500. The medication can affect the results of these tests.


Inform your doctor about any medications you are currently taking, including:

  • Allopurinol (for gout): Increases the risk of allergic skin reactions.
  • Probenecid (for gout): May require Amoxi-Denk 500 dose adjustment.
  • Blood Thinners (e.g., Warfarin): May necessitate additional blood tests.
  • Other Antibiotics: Taking other antibiotics simultaneously can reduce Amoxi-Denk 500’s effectiveness.
  • Methotrexate (for cancer and severe psoriasis treatment): May cause more side effects when used with Amoxi-Denk 500.

Pregnancy and Breastfeeding

If you are pregnant, breastfeeding, planning to become pregnant, or suspect you may be pregnant, consult your healthcare provider before taking Amoxi-Denk 500.

Driving and Using Machines

Amoxi-Denk 500 can induce side effects, such as allergic reactions, dizziness, and convulsions, which may impair your ability to drive or operate machinery. It is crucial to avoid such activities unless you are feeling well.

How to Take Amoxi-Denk 500

Here are some important guidelines for taking Amoxi-Denk 500:

  • Administration: Swallow the tablet with water.
  • Dosing: Space out the doses evenly during the day, with at least a 4-hour interval.
  • Dosage: The prescribed dose depends on several factors, including the patient’s age, weight, kidney function, the severity, and location of the infection, and the suspected or confirmed pathogens.

Dosage Guidelines

Children Weighing Less Than 40 kg:

  • The dosage is determined based on the child’s body weight in kilograms.
  • Typically, the daily dose ranges from 40 mg to 90 mg per kilogram of body weight, divided into two or three doses.
  • The maximum recommended dose is 100 mg per kilogram of body weight per day.

Adults, Elderly Patients, and Children Weighing 40 kg or More:

  • For general infections, the usual dose ranges from 250 mg to 500 mg taken three times a day.
  • In cases of severe infections, it may increase to 750 mg to 1 g, three times a day.
  • Urinary tract infections may require a 3 g dose, taken twice daily for one day.
  • Lyme disease treatment varies depending on the stage: 4 g per day for the early stage and up to 6 g per day for severe or disseminated cases.

How Long to Take Amoxi-Denk 500

Continue taking Amoxi-Denk 500 for the duration specified by your doctor, even if you start feeling better. Completing the full course of antibiotics is crucial to ensure all bacteria are eradicated. Stopping early could lead to a relapse of the infection.

Possible Side Effects

As with any medication, Amoxi-Denk 500 may cause side effects in some individuals. Here’s what you need to know:

Serious Side Effects (Seek Immediate Medical Attention)

The following side effects are rare but require urgent medical attention:

  • Allergic Reactions: Symptoms include skin itching, swelling of the face, lips, tongue, or difficulties in breathing.
  • Skin Reactions: These may manifest as rashes, bruises, joint pain, and kidney problems.
  • Delayed Allergic Reaction: This can occur around 7 to 12 days after starting amoxicillin and includes rashes, fever, joint pains, and swollen lymph nodes.
  • Erythema Multiforme: Symptoms may include reddening, blistering, and peeling of the skin.

Common Side Effects (Consult Your Doctor)

These side effects are usually mild and may include:

  • Nausea
  • Vomiting
  • Diarrhea

Side Effects with Unknown Frequency

Some side effects have been reported with unknown frequency, including:

  • Liver Disorders
  • Kidney Disorders
  • Reduced Number of White Blood Cells
  • Severe Diarrhea (Pseudomembranous Colitis)

If you experience any side effects, especially severe or unusual ones, contact your healthcare provider immediately.


  • Store Amoxi-Denk 500 at or below 25°C in a dry place.
  • Keep it out of the reach and sight of children.


Amoxi-Denk 500 is a powerful antibiotic that can effectively treat bacterial infections. It’s crucial to follow your doctor’s recommendations regarding dosage and duration of treatment. Be aware of potential side effects, and if you have any concerns or experience unusual symptoms, consult your healthcare provider. In case of severe reactions, seek immediate medical attention. Always take antibiotics as prescribed to maximize their effectiveness and prevent antibiotic resistance.